Dental pulp is a highly specialized mesenchymal tissue that has a limited regeneration
capacity due to anatomical arrangement and post-mitotic nature of odontoblastic cells. Entire
pulp amputation followed by pulp space disinfection and filling with an artificial material …

Tumor angiogenesis and lymphangiogenesis are key features of tumor progression and
metastasis. The role of tumor cells-derived factors in the promotion of associated
angiogenesis and lymphangiogenesis is much studied and, no doubt, very important for the …

Tissue engineering is an interdisciplinary field that combines the principles of engineering,
material and biological sciences toward the development of therapeutic strategies and
biological substitutes that restore, maintain, replace or improve biological functions. The …

The dental pulp is a loose connective tissue located within rigid dentinal walls. Therefore,
when subjected to a stimulus, the pulpal tissue has little expansion capacity. The defense
mechanisms of this tissue include the formation of tertiary dentin as well as the production of …

SHED (stem cells from human exfoliated deciduous teeth) represent a population of
postnatal stem cells capable of extensive proliferation and multipotential differentiation.
Primary teeth may be an ideal source of postnatal stem cells to regenerate tooth structures …

Aim: The aim of this paper is to present a review and discussion of the current status of stem
cell research with regard to tooth generation. Background: Stem cells have been isolated
from the pulp tissue of both deciduous and permanent teeth as well as from the periodontal …

Stem cells are undifferentiated cells that have the capacity to self-renew. They have been
discovered in many adult tissues, including teeth. The Dental Pulp Stem Cells are involved
in dentinal repair by activation of growth factors, released after caries process and have the …

Proapoptotic and antiapoptotic proteins in the Bcl family are key regulators of programmed
cell death. It is the interaction between these molecules that determines cellular response to
apoptotic signals, making them attractive targets for therapeutic intervention. In recent …

Alginate hydrogel (AH) has intrinsic physical and biological limitations that hinder its broader
application in tissue engineering. We hypothesized that the inclusion of nanofibers in the
hydrogel and the use of a biotemplate that mimics nature would enhance the translational …

The aim of this study was to evaluate the influence of the poly-L-lactic acid (PLLA)-based
scaffold's pore size on the proliferation and differentiation of dental pulp stem cells (DPSCs).
The scaffolds were prepared in pulp chambers of 1-mm-thick tooth slices from third molars …