Acute coronary syndromes (ACS) represent the main clinical manifestation of atherosclerotic
progression in the coronary district. Thrombosis plays a critical role in the patho-anatomical
of ACS, as disruption of an atherosclerotic plaque exposes flowing blood to subendothelial …

Biomarkers are an important aspect of research linking psychosocial stress and health. This
article aims to characterize the biological pathways that may mediate the relationship
between socioeconomic position (SEP) and cardiovascular disease (CVD) and address …

Motivated by the challenge of risk assessment in a heterogeneous population and guided by
advances in our knowledge of the pathobiology of cardiovascular diseases (CVD), basic
and clinical scientists have maintained substantial interest in the development and …

There are several reports of myeloperoxidase (MPO) playing an important role in acute
coronary syndromes (ACS). Interleukin-17 (IL-17) is a pro-inflammatory cytokine produced
by activated CD4 T cells that has a chemotactic and activating effect on neutrophils. It has …

Objective To investigate the differential gene expression profiles in coronary heart disease
(CHD) patients of blood-stasis syndrome (BSS) by oligonucleotide microarray technique,
and the clinical significance of target gene. Methods Subjects were assigned to CHD …

Background: Cardiopulmonary bypass (CPB) has been associated with activation and injury
of endothelial cells, probably responsible for the systemic inflammatory response syndrome
(SIRS) taking place in these patients. Methods: We measured plasma concentrations of …

RESULTS The frequency of the-174C allele (mutant) was lower in Tunisians than in
Europeans, and the distribution of-174 G> C genotypes was similar between CAD patients
and control subjects. Moreover, compared to GG genotype carriers,-174C allele carriage did …

In this study, the dynamic expression of granule membrane protein-140 (GMP-140), tissue-
type plasminogen activator (t-PA), high-sensitivity C-reactive protein (hs-CRP), interleukin
(IL)-6, matrix metalloproteinase (MMP)-9 and tissue inhibitor of metalloproteinase (TIMP)-1 …

Objective To investigate whether sodium tanshinone IIA silate (STS) as an add-on therapy to
conventional treatment may provide additional benefits for patients with unstable angina
pectoris (UAP) and is associated with changes in profiles of serum inflammatory factors …

Objective: To investigate the concentrations of plasma cytokines and Galectin-3 (Gal-3) as
inflammatory markers in patients with acute myocardial infarction (AMI). Methods: The study
population consisted of 29 patients with AMI and 29 healthy control subjects. We measured …