Mesenchymal stem cells (MSCs) from Wharton's jelly present high plasticity and low
immunogenicity, turning them into a desirable form of cell therapy for the injured nervous
system. Their isolation, expansion, and characterization have been performed from …

Peripheral nerves have the intrinsic capacity of self-regeneration after traumatic injury but
the extent of the regeneration is often very poor. Increasing evidence demonstrates that
mesenchymal stem/stromal cells (MSCs) may play an important role in tissue regeneration …

The treatment of peripheral nerve injuries remains one of the greatest challenges of
neurosurgery, as functional recover is rarely satisfactory in these patients. Recently,
biodegradable nerve guides have shown great potential for enhancing nerve regeneration …

AIM: To study the therapeutic effect of three tube-guides with electrical conductivity
associated to mesenchymal stem cells (MSCs) on neuro-muscular regeneration after
neurotmesis. METHODS: Rats with 10-mm gap nerve injury were tested using polyvinyl …

Background: The aim of this study was to determine the effects of amniotic membrane
impregnated with betamethasone on regeneration of transected sciatic nerve injury in adult
albino Wister rats. Methods: In this research, 42 male adult rats were divided into six equal …

Surgical reconstruction of peripheral nerves injuries with wide substance-loss is still a
challenge. Many studies focused on the development of artificial nerve conduits made of
synthetic or biological materials but the ideal device has not yet been identified. Here, we …

Recent advances in Regenerative Biology and Regenerative Medicine are impressive and
in the last years the scientific community has witnessed the emergence of many new
concepts and discoveries. Until a few years ago, biological tissues were regarded as unable …

The therapeutic effect of three polyvinyl alcohol (PVA) membranes loaded with electrically
conductive materials‐carbon nanotubes (PVA‐CNTs) and polypyrrole (PVA‐PPy)‐were
tested in vivo for neuro‐muscular regeneration after an axonotmesis injury in the rat sciatic …

Background: Although peripheral nerves show capacity for regeneration after injury to a
certain extent, the extent of regeneration is not remarkable. Previous studies have
suggested that through the production of growth factors or extracellular matrix components …

Peripheral nerve regeneration is a serious clinical problem. Presently, there are several
nerve tube‐guides available in the market, however with some limitations. The goal of this
work was the development of a biomaterial with high electrical conductivity to produce tube …