Peripheral nerve injury continues to pose a clinical hurdle despite its frequency and
advances in treatment. Unlike the central nervous system, neurons of the peripheral nervous
system have a greater ability to regenerate. However, due to a number of confounding …

The discovery of mesenchymal stem cells (MSCs) in perinatal sources, such as the amniotic
fluid (AF) and the umbilical connective tissue, the so-called Wharton's jelly (WJ), has
transformed them into promising stem cell grafts for the application in regenerative medicine …

Mesenchymal stem cells are posing as a promising character in the most recent therapeutic
strategies and, since their discovery, extensive knowledge on their features and functions
has been gained. In recent years, innovative sources have been disclosed in alternative to …

Objective Peripheral nerve injuries comprise significant portion of the nervous system
injuries. Although peripheral nerves show some capacity of regeneration after injury, but the
extent of regeneration is not remarkable. Regeneration might be through the activity of the …

Peripheral nerve injury has remained a substantial clinical complication with no satisfactory
treatment options. Despite the great development in the field of microsurgery, some severe
types of neural injuries cannot be treated without causing tension to the injured nerve. Thus …

Background Peripheral nerve injuries represent a clinical problem with insufficient or
unsatisfactory treatment options. Functional outcome with nerve guidance conduits was
unsatisfactory in nerve defects with increased gap size. So, cell therapy may benefit as a tool …

The functional and structural performance of a 5 cm synthetic small diameter vascular graft
(SDVG) produced by the copolymerization of polyvinyl alcohol hydrogel with low molecular
weight dextran (PVA/Dx graft) associated to mesenchymal stem cells (MSCs)-based …

AIM: To study the therapeutic effect of three tube-guides with electrical conductivity
associated to mesenchymal stem cells (MSCs) on neuro-muscular regeneration after
neurotmesis. METHODS: Rats with 10-mm gap nerve injury were tested using polyvinyl …

This paper reviews the recent research progress in the past several years on promoting
peripheral nerve recovery using stem and progenitory cells. The emphasis is placed on
studies aimed at assessing various stem cells capable of expressing neurotrophic and …

Peripheral nerve injury has remained a substantial clinical complication with no satisfactory
treatment options. Despite the great development in the field of microsurgery, some severe
types of neural injuries cannot be treated without causing tension to the injured nerve. Thus …