Histone deacetylase 1 and 2-controlled embryonic development and cell differentiation. R Brunmeir, S Lagger, C Seiser International Journal of Developmental Biology 53, 2009 | 207 | 2009 |
The cyclin-dependent kinase inhibitor p21 is a crucial target for histone deacetylase 1 as a regulator of cellular proliferation G Zupkovitz, R Grausenburger, R Brunmeir, S Senese, J Tischler, J Jurkin, ... Molecular and cellular biology 30 (5), 1171-1181, 2010 | 172 | 2010 |
Distinct and redundant functions of histone deacetylases HDAC1 and HDAC2 in proliferation and tumorigenesis J Jurkin, G Zupkovitz, S Lagger, R Grausenburger, A Hagelkruys, ... Cell cycle 10 (3), 406-412, 2011 | 149 | 2011 |
The role of activator protein-1 (AP-1) family members in CD30-positive lymphomas I Garces de los Fayos Alonso, HC Liang, SD Turner, S Lagger, O Merkel, ... Cancers 10 (4), 93, 2018 | 143 | 2018 |
PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas D Laimer, H Dolznig, K Kollmann, PW Vesely, M Schlederer, O Merkel, ... Nature medicine 18 (11), 1699-1704, 2012 | 142 | 2012 |
The specific role of histone deacetylase 2 in adult neurogenesis M Jawerka, D Colak, L Dimou, C Spiller, S Lagger, RL Montgomery, ... Neuron glia biology 6 (2), 93-107, 2010 | 122 | 2010 |
MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain S Lagger, JC Connelly, G Schweikert, S Webb, J Selfridge, ... PLoS genetics 13 (5), e1006793, 2017 | 120 | 2017 |
The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome K Brown, J Selfridge, S Lagger, J Connelly, D De Sousa, A Kerr, S Webb, ... Human molecular genetics 25 (3), 558-570, 2016 | 100 | 2016 |
A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog A Hagelkruys, S Lagger, J Krahmer, A Leopoldi, M Artaker, O Pusch, ... Development 141 (3), 604-616, 2014 | 91 | 2014 |
CD4+ T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2 N Boucheron, R Tschismarov, L Goeschl, MA Moser, S Lagger, ... Nature immunology 15 (5), 439-448, 2014 | 87 | 2014 |
Epigenetic regulation of a murine retrotransposon by a dual histone modification mark R Brunmeir, S Lagger, E Simboeck, A Sawicka, G Egger, A Hagelkruys, ... PLoS genetics 6 (4), e1000927, 2010 | 66 | 2010 |
Self-organization phenomena in embryonic stem cell-derived embryoid bodies: axis formation and breaking of symmetry during cardiomyogenesis C Fuchs, M Scheinast, W Pasteiner, S Lagger, M Hofner, A Hoellrigl, ... Cells Tissues Organs 195 (5), 377-391, 2012 | 62 | 2012 |
Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia S Kollmann, E Grundschober, B Maurer, W Warsch, R Grausenburger, ... Leukemia 33 (7), 1583-1597, 2019 | 54 | 2019 |
Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans S Lagger, D Meunier, M Mikula, R Brunmeir, M Schlederer, M Artaker, ... The EMBO journal 29 (23), 3992-4007, 2010 | 49 | 2010 |
Expression of class I histone deacetylases during chick and mouse development C Murko, S Lagger, M Steiner, C Seiser, C Schoefer, O Pusch The International journal of developmental biology 54 (10), 1527, 2010 | 44 | 2010 |
Histone deacetylase inhibitor Trichostatin A induces neural tube defects and promotes neural crest specification in the chicken neural tube C Murko, S Lagger, M Steiner, C Seiser, C Schoefer, O Pusch Differentiation 85 (1-2), 55-66, 2013 | 42 | 2013 |
STAT3‐dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer M Oberhuber, M Pecoraro, M Rusz, G Oberhuber, M Wieselberg, ... Molecular Systems Biology 16 (4), e9247, 2020 | 40 | 2020 |
CDK6 coordinates JAK2V617F mutant MPN via NF-κB and apoptotic networks IZ Uras, B Maurer, H Nivarthi, P Jodl, K Kollmann, M Prchal-Murphy, ... Blood, The Journal of the American Society of Hematology 133 (15), 1677-1690, 2019 | 36 | 2019 |
A STAT5B–CD9 axis determines self-renewal in hematopoietic and leukemic stem cells S Kollmann, R Grausenburger, T Klampfl, M Prchal-Murphy, K Bastl, ... Blood, The Journal of the American Society of Hematology 138 (23), 2347-2359, 2021 | 29 | 2021 |
KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis T Limberger, M Schlederer, K Trachtová, I Garces de los Fayos Alonso, ... Molecular Cancer 21 (1), 89, 2022 | 26 | 2022 |