| Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque … H Oakley, SL Cole, S Logan, E Maus, P Shao, J Craft, ... Journal of Neuroscience 26 (40), 10129-10140, 2006 | 3305 | 2006 |
| BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease M Ohno, EA Sametsky, LH Younkin, H Oakley, SG Younkin, M Citron, ... Neuron 41 (1), 27-33, 2004 | 677 | 2004 |
| Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1 RM Costa, NB Federov, JH Kogan, GG Murphy, J Stern, M Ohno, ... nature 415 (6871), 526-530, 2002 | 663 | 2002 |
| α-CaMKII-dependent plasticity in the cortex is required for permanent memory PW Frankland, C O'Brien, M Ohno, A Kirkwood, AJ Silva Nature 411 (6835), 309-313, 2001 | 519 | 2001 |
| Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits DS Yang, P Stavrides, PS Mohan, S Kaushik, A Kumar, M Ohno, ... Brain 134 (1), 258-277, 2011 | 485 | 2011 |
| BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice M Ohno, SL Cole, M Yasvoina, J Zhao, M Citron, R Berry, JF Disterhoft, ... Neurobiology of disease 26 (1), 134-145, 2007 | 362 | 2007 |
| Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model R Kimura, M Ohno Neurobiology of disease 33 (2), 229-235, 2009 | 346 | 2009 |
| Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1 M Ohno, L Chang, W Tseng, H Oakley, M Citron, WL Klein, R Vassar, ... European Journal of Neuroscience 23 (1), 251-260, 2006 | 323 | 2006 |
| 7, 8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease L Devi, M Ohno Neuropsychopharmacology 37 (2), 434-444, 2012 | 293 | 2012 |
| Mechanisms underlying insulin deficiency-induced acceleration of β-amyloidosis in a mouse model of Alzheimer's disease L Devi, MJ Alldred, SD Ginsberg, M Ohno PloS one 7 (3), e32792, 2012 | 174 | 2012 |
| PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease L Devi, M Ohno Neurobiology of aging 35 (10), 2272-2281, 2014 | 166 | 2014 |
| Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer’s disease transgenic mice R Kimura, L Devi, M Ohno Journal of neurochemistry 113 (1), 248-261, 2010 | 161 | 2010 |
| Phospho-eIF2α level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice L Devi, M Ohno PloS one 5 (9), e12974, 2010 | 146 | 2010 |
| Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice L Devi, M Ohno Neurobiology of disease 45 (1), 417-424, 2012 | 145 | 2012 |
| Sex-and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease L Devi, MJ Alldred, SD Ginsberg, M Ohno Molecular brain 3, 1-11, 2010 | 142 | 2010 |
| Roles of eIF2α kinases in the pathogenesis of Alzheimer’s disease M Ohno Frontiers in molecular neuroscience 7, 22, 2014 | 130 | 2014 |
| Inducible, pharmacogenetic approaches to the study of learning and memory M Ohno, PW Frankland, AP Chen, RM Costa, AJ Silva Nature neuroscience 4 (12), 1238-1243, 2001 | 116 | 2001 |
| Increased neuronal excitability, synaptic plasticity, and learning in aged Kvβ1. 1 knockout mice GG Murphy, NB Fedorov, KP Giese, M Ohno, E Friedman, R Chen, ... Current Biology 14 (21), 1907-1915, 2004 | 114 | 2004 |
| Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis DS Yang, P Stavrides, PS Mohan, S Kaushik, A Kumar, M Ohno, ... Autophagy 7 (7), 788-789, 2011 | 112 | 2011 |
| Blockade of hippocampal nicotinic receptors impairs working memory but not reference memory in rats M Ohno, T Yamamoto, S Watanabe Pharmacology Biochemistry and Behavior 45 (1), 89-93, 1993 | 111 | 1993 |
Alcino J SilvaDistinguished Professor of Neurobiology, UCLAVerified email at mednet.ucla.edu
