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Volker Hovestadt
Volker Hovestadt
Assistant Professor of Pediatrics; Dana-Farber, BCH & Broad Institute
Email confirmado em dfci.harvard.edu - Página inicial
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Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226-231, 2012
26002012
DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469-474, 2018
21742018
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer Cell 22 (4), 425-437, 2012
19302012
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups
KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ...
Cancer Cell 27 (5), 728-743, 2015
10662015
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100-105, 2012
9402012
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
9342017
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ...
Science 355 (6332), eaai8478, 2017
8312017
New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs
D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ...
Cell 164 (5), 1060-1072, 2016
8072016
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ...
Cancer cell 25 (3), 393-405, 2014
8012014
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927-932, 2013
7912013
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ...
Cancer cell 24 (5), 660-672, 2013
7322013
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
P van Galen, V Hovestadt, MH Wadsworth II, TK Hughes, GK Griffin, ...
Cell 176 (6), 1265-1281. e24, 2019
7222019
DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis
F Sahm, D Schrimpf, D Stichel, DTW Jones, T Hielscher, S Schefzyk, ...
The Lancet Oncology 18 (5), 682-694, 2017
6942017
Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
PA Northcott, C Lee, T Zichner, AM Stütz, S Erkek, D Kawauchi, DJH Shih, ...
Nature 511 (7510), 428-434, 2014
6582014
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
6252014
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ...
Science 360 (6386), 331-335, 2018
5322018
Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes
PD Johann, S Erkek, M Zapatka, K Kerl, I Buchhalter, V Hovestadt, ...
Cancer cell 29 (3), 379-393, 2016
5172016
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma …
DE Reuss, F Sahm, D Schrimpf, B Wiestler, D Capper, C Koelsche, ...
Acta neuropathologica 129 (1), 133-146, 2015
4982015
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.
J Richter, M Schlesner, S Hoffmann, M Kreuz, E Leich, B Burkhardt, ...
Nature genetics, 2012
4792012
BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1
M Tönjes, S Barbus, YJ Park, W Wang, M Schlotter, AM Lindroth, ...
Nature medicine 19 (7), 901-908, 2013
4622013
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