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Kamil Nosol
Kamil Nosol
Verified email at mol.biol.ethz.ch
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Year
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1
K Nosol, K Romane, RN Irobalieva, A Alam, J Kowal, N Fujita, KP Locher
Proceedings of the National Academy of Sciences 117 (42), 26245-26253, 2020
1572020
Structure and drug resistance of the Plasmodium falciparum transporter PfCRT
J Kim, YZ Tan, KJ Wicht, SK Erramilli, SK Dhingra, J Okombo, J Vendome, ...
Nature 576 (7786), 315-320, 2019
1542019
Structure and mechanism of the ER-based glucosyltransferase ALG6
JS Bloch, G Pesciullesi, J Boilevin, K Nosol, RN Irobalieva, T Darbre, ...
Nature 579 (7799), 443-447, 2020
552020
Discovery and characterization of potent dual P-glycoprotein and CYP3A4 inhibitors: design, synthesis, cryo-EM analysis, and biological evaluations
S Urgaonkar, K Nosol, AM Said, NN Nasief, Y Bu, KP Locher, JYN Lau, ...
Journal of Medicinal Chemistry 65 (1), 191-216, 2021
302021
Structure of human NTCP reveals the basis of recognition and sodium-driven transport of bile salts into the liver
H Liu, RN Irobalieva, R Bang-Sørensen, K Nosol, S Mukherjee, P Agrawal, ...
Cell research 32 (8), 773-776, 2022
242022
Structural basis of lipopolysaccharide maturation by the O-antigen ligase
KU Ashraf, R Nygaard, ON Vickery, SK Erramilli, CM Herrera, ...
Nature 604 (7905), 371-376, 2022
242022
Structures of ABCB4 provide insight into phosphatidylcholine translocation
K Nosol, R Bang-Sørensen, RN Irobalieva, SK Erramilli, B Stieger, ...
Proceedings of the National Academy of Sciences 118 (33), e2106702118, 2021
242021
Structure of human drug transporters OATP1B1 and OATP1B3
AD Ciută, K Nosol, J Kowal, S Mukherjee, AS Ramírez, B Stieger, ...
Nature Communications 14 (1), 5774, 2023
62023
Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry
SA Leonhardt, MD Purdy, JR Grover, Z Yang, S Poulos, WE McIntire, ...
Nature Communications 14 (1), 4368, 2023
62023
Physicochemical properties and solubility of hydrochloride mucolytic agents
A Pobudkowska, A Śliwińska, K Nosol
Journal of Solution Chemistry 50 (5), 652-666, 2021
52021
CryoEM structures of the human HIV-1 restriction factor SERINC3 and function as a lipid transporter
SA Leonhardt, MD Purdy, JR Grover, Z Yang, S Poulos, WE McIntire, ...
bioRxiv, 2022.07. 06.498924, 2022
42022
Catalytic hydrogenation for a biomass-derived dicarboxylic acid valorisation with an ionic liquid and CO2 towards a perspective host guest building block molecule
E Bogel-Łukasik, K Nosol, D Silva, CI Melo
The Journal of Supercritical Fluids 133, 542-547, 2018
32018
Physicochemical properties and solubilities of drugs hydrochlorides in water and alcohols
A Pobudkowska, A Szabłowska, K Nosal
International Journal of Pharma Research & Review 5, 2016
22016
Structure of antiviral drug bulevirtide bound to hepatitis B and D virus receptor protein NTCP
H Liu, D Zakrzewicz, K Nosol, RN Irobalieva, S Mukherjee, ...
Nature Communications 15 (1), 2476, 2024
12024
Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP
H Liu, RN Irobalieva, J Kowal, D Ni, K Nosol, R Bang-Sørensen, ...
Nature Communications 14 (1), 7296, 2023
12023
Production of Human ABC Transporters and Oligosaccharyltransferase Complexes for Structural Studies
AS Ramírez, K Nosol, KP Locher
Heterologous Expression of Membrane Proteins: Methods and Protocols, 273-294, 2022
12022
Structure of hepatitis B/D antiviral drug Bulevirtide bound to its receptor protein NTCP
H Liu, D Zakrzewicz, K Nosol, RN Irobalieva, S Mukherjee, ...
bioRxiv, 2024.01. 22.576510, 2024
2024
Structural basis for CorA channel gating using conformation-specific synthetic antigen binders and single-particle cryo-EM
SK Erramilli, PK Dominik, T Li, K Nosol, P Tokarz, P Dutka, M Zhao, ...
Biophysical Journal 122 (3), 447a, 2023
2023
Structural studies of human ABC transporters ABCB1 and ABCB4
K Nosol
ETH Zurich, 2022
2022
Visualizing Conformational Changes of the Magnesium Channel Cora using Synthetic Antibodies
SK Erramilli, T Li, K Nosol, P Tokarz, P Dutka, PK Dominik, E Perozo, ...
Biophysical Journal 118 (3), 273a, 2020
2020
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