| Biological, clinical and population relevance of 95 loci for blood lipids TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ... Nature 466 (7307), 707-713, 2010 | 4039 | 2010 |
| Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012 | 2541 | 2012 |
| From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus K Musunuru, A Strong, M Frank-Kamenetsky, NE Lee, T Ahfeldt, KV Sachs, ... Nature 466 (7307), 714-719, 2010 | 1242 | 2010 |
| Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia K Musunuru, JP Pirruccello, R Do, GM Peloso, C Guiducci, C Sougnez, ... New England Journal of Medicine 363 (23), 2220-2227, 2010 | 778 | 2010 |
| Genetics of 35 blood and urine biomarkers in the UK Biobank N Sinnott-Armstrong, Y Tanigawa, D Amar, N Mars, C Benner, M Aguirre, ... Nature genetics 53 (2), 185-194, 2021 | 487 | 2021 |
| Genetic interleukin 6 signaling deficiency attenuates cardiovascular risk in clonal hematopoiesis AG Bick, JP Pirruccello, GK Griffin, N Gupta, S Gabriel, D Saleheen, ... Circulation 141 (2), 124-131, 2020 | 308 | 2020 |
| Lp (a)(lipoprotein [a]) concentrations and incident atherosclerotic cardiovascular disease: new insights from a large national biobank AP Patel, M Wang, JP Pirruccello, PT Ellinor, K Ng, S Kathiresan, ... Arteriosclerosis, thrombosis, and vascular biology 41 (1), 465-474, 2021 | 244 | 2021 |
| Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy JP Pirruccello, A Bick, M Wang, M Chaffin, S Friedman, J Yao, X Guo, ... Nature communications 11 (1), 2254, 2020 | 168 | 2020 |
| Candidate Gene Association Resource (CARe) design, methods, and proof of concept K Musunuru, G Lettre, T Young, DN Farlow, JP Pirruccello, KG Ejebe, ... Circulation: Cardiovascular Genetics 3 (3), 267-275, 2010 | 162 | 2010 |
| Deep learning enables genetic analysis of the human thoracic aorta JP Pirruccello, MD Chaffin, EL Chou, SJ Fleming, H Lin, M Nekoui, ... Nature genetics 54 (1), 40-51, 2022 | 118 | 2022 |
| Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection SM Zekavat, SH Lin, AG Bick, A Liu, K Paruchuri, C Wang, MM Uddin, ... Nature medicine 27 (6), 1012-1024, 2021 | 117 | 2021 |
| Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol YX Xu, V Redon, H Yu, W Querbes, J Pirruccello, A Liebow, A Deik, ... Atherosclerosis 268, 196-206, 2018 | 105 | 2018 |
| Advances in genetics show the need for extending screening strategies for autosomal dominant hypercholesterolaemia MM Motazacker, J Pirruccello, R Huijgen, R Do, S Gabriel, J Peter, ... European heart journal 33 (11), 1360-1366, 2012 | 103 | 2012 |
| Premature menopause, clonal hematopoiesis, and coronary artery disease in postmenopausal women MC Honigberg, SM Zekavat, A Niroula, GK Griffin, AG Bick, JP Pirruccello, ... Circulation 143 (5), 410-423, 2021 | 97 | 2021 |
| A Novel APOB Mutation Identified by Exome Sequencing Cosegregates With Steatosis, Liver Cancer, and Hypocholesterolemia AB Cefalù, JP Pirruccello, D Noto, S Gabriel, V Valenti, N Gupta, R Spina, ... Arteriosclerosis, thrombosis, and vascular biology 33 (8), 2021-2025, 2013 | 94 | 2013 |
| Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis PG Kim, A Niroula, V Shkolnik, M McConkey, AE Lin, M Słabicki, JP Kemp, ... Journal of Experimental Medicine 218 (12), e20211872, 2021 | 92 | 2021 |
| Monogenic and polygenic contributions to atrial fibrillation risk: results from a national biobank SH Choi, SJ Jurgens, LC Weng, JP Pirruccello, C Roselli, M Chaffin, ... Circulation research 126 (2), 200-209, 2020 | 88 | 2020 |
| Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank SJ Jurgens, SH Choi, VN Morrill, M Chaffin, JP Pirruccello, JL Halford, ... Nature genetics 54 (3), 240-250, 2022 | 85 | 2022 |
| Clonal haematopoiesis and risk of chronic liver disease WJ Wong, C Emdin, AG Bick, SM Zekavat, A Niroula, JP Pirruccello, ... Nature 616 (7958), 747-754, 2023 | 67 | 2023 |
| Machine learning enables new insights into genetic contributions to liver fat accumulation ME Haas, JP Pirruccello, SN Friedman, M Wang, CA Emdin, VH Ajmera, ... Cell genomics 1 (3), 2021 | 66 | 2021 |
Patrick T. Ellinor, MD, PhDBroad Institute of MIT and Harvard, Massachusetts General Hospital, Harvard Medical SchoolEmail confirmado em mgh.harvard.edu
