Glen Ropella
Glen Ropella
Tempus Dictum, Inc.
Email confirmado em tempusdictum.com - Página inicial
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Open-ended evolution: Perspectives from the OEE workshop in York
T Taylor, M Bedau, A Channon, D Ackley, W Banzhaf, G Beslon, E Dolson, ...
Artificial life 22 (3), 408-423, 2016
782016
At the biological modeling and simulation frontier
CA Hunt, GEP Ropella, TN Lam, J Tang, SHJ Kim, JA Engelberg, ...
Pharmaceutical research 26 (11), 2369-2400, 2009
732009
Physiologically based synthetic models of hepatic disposition
CA Hunt, GEP Ropella, L Yan, DY Hung, MS Roberts
Journal of pharmacokinetics and pharmacodynamics 33 (6), 737-772, 2006
702006
Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver
L Yan, GEP Ropella, S Park, MS Roberts, CA Hunt
Pharmaceutical research 25 (5), 1023-1036, 2008
582008
Essential operating principles for tumor spheroid growth
JA Engelberg, GEP Ropella, CA Hunt
BMC systems biology 2 (1), 110, 2008
532008
Software engineering considerations for individual‐based models
GE Ropella, SF Railsback, SK Jackson
Natural resource modeling 15 (1), 5-22, 2002
442002
Predictions of hepatic disposition properties using a mechanistically realistic, physiologically based model
L Yan, S Sheihk-Bahaei, S Park, GEP Ropella, CA Hunt
Drug metabolism and disposition 36 (4), 759-768, 2008
422008
Dichotomies between computational and mathematical models
CA Hunt, GEP Ropella, S Park, J Engelberg
Nature biotechnology 26 (7), 737-738, 2008
412008
Agent‐based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity
CA Hunt, RC Kennedy, SHJ Kim, GEP Ropella
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 5 (4), 461-480, 2013
382013
Tracing multiscale mechanisms of drug disposition in normal and diseased livers
S Park, SHJ Kim, GEP Ropella, MS Roberts, CA Hunt
Journal of Pharmacology and Experimental Therapeutics 334 (1), 124-136, 2010
332010
Relational grounding facilitates development of scientifically useful multiscale models
CA Hunt, GEP Ropella, T ning Lam, AD Gewitz
Theoretical Biology and Medical Modelling 8 (1), 1-23, 2011
282011
Computational strategies unravel and trace how liver disease changes hepatic drug disposition
S Park, GEP Ropella, SHJ Kim, MS Roberts, CA Hunt
Journal of Pharmacology and Experimental Therapeutics 328 (1), 294-305, 2009
262009
Using heuristic models to bridge the gap between analytic and experimental models in biology
GE Ropella, CA Hunt, DA Nag
Agent-Directed Simulation Symposium, Vol. Simulation Series 37 (2), 182-190, 2005
252005
Toward modular biological models: defining analog modules based on referent physiological mechanisms
BK Petersen, GEP Ropella, CA Hunt
BMC systems biology 8 (1), 95, 2014
222014
Cloud computing and validation of expandable in silico livers
GEP Ropella, CA Hunt
BMC systems biology 4 (1), 1-13, 2010
182010
Methodological considerations of heuristic modeling of biological systems
GEP Ropella, CA Hunt, S Sheikh-Bahaei
Proceedings of the 9th world multi-conference on systemics, cybernetics and …, 2005
182005
Similarity measures for automated comparison of in silico and in vitro experimental results
GEP Ropella, DA Nag, CA Hunt
Proceedings of the 25th Annual International Conference of the IEEE …, 2003
182003
Biomimetic in silico devices
CA Hunt, GEP Ropella, MS Roberts, L Yan
International Conference on Computational Methods in Systems Biology, 34-42, 2004
152004
Competing mechanistic hypotheses of acetaminophen-induced hepatotoxicity challenged by virtual experiments
AK Smith, BK Petersen, GEP Ropella, RC Kennedy, N Kaplowitz, ...
PLoS computational biology 12 (12), e1005253, 2016
142016
In silico representation of the liver-connecting function to anatomy, physiology and heterogeneous microenvironments
L Yan, CA Hunt, GEP Ropella, MS Roberts
The 26th Annual International Conference of the IEEE Engineering in Medicine …, 2004
142004
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