Specific T helper cell requirement for optimal induction of cytotoxic T lymphocytes against major histocompatibility complex class II negative tumors F Ossendorp, E Mengedé, M Camps, R Filius, CJM Melief The Journal of experimental medicine 187 (5), 693-702, 1998 | 744 | 1998 |
Decreased tumor surveillance in perforin-deficient mice. ME van den Broek, D Kägi, F Ossendorp, R Toes, S Vamvakas, WK Lutz, ... The Journal of experimental medicine 184 (5), 1781-1790, 1996 | 736 | 1996 |
Vaccines for established cancer: overcoming the challenges posed by immune evasion SH van der Burg, R Arens, F Ossendorp, T van Hall, CJM Melief Nature Reviews Cancer 16 (4), 219-233, 2016 | 716 | 2016 |
Therapeutic cancer vaccines CJM Melief, T van Hall, R Arens, F Ossendorp, SH van der Burg The Journal of clinical investigation 125 (9), 3401-3412, 2015 | 661 | 2015 |
CD4 T cells and their role in antitumor immune responses REM Toes, F Ossendorp, R Offringa, CJM Melief The Journal of experimental medicine 189 (5), 753-756, 1999 | 660 | 1999 |
Proteasome and peptidase function in MHC-class-I-mediated antigen presentation PM Kloetzel, F Ossendorp Current opinion in immunology 16 (1), 76-81, 2004 | 528 | 2004 |
CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope A Skowera, RJ Ellis, R Varela-Calviño, S Arif, GC Huang, C Van-Krinks, ... The Journal of clinical investigation 118 (10), 3390-3402, 2008 | 455 | 2008 |
MHC II in dendritic cells is targeted to lysosomes or T cell‐induced exosomes via distinct multivesicular body pathways SI Buschow, ENM Nolte‐‘t Hoen, G Van Niel, MS Pols, T Ten Broeke, ... Traffic 10 (10), 1528-1542, 2009 | 436 | 2009 |
Efficient identification of novel Hla-A* 0201–Presented Cytotoxic T Lymphocyte epitopes in the widely expressed tumor antigen prame by Proteasome-Mediated digestion analysis JH Kessler, NJ Beekman, SA Bres-Vloemans, P Verdijk, PA van Veelen, ... The Journal of experimental medicine 193 (1), 73-88, 2001 | 366 | 2001 |
Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes GGM Pinkse, OHM Tysma, CAM Bergen, MGD Kester, F Ossendorp, ... Proceedings of the National Academy of Sciences 102 (51), 18425-18430, 2005 | 357 | 2005 |
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells M Kleijmeer, G Ramm, D Schuurhuis, J Griffith, M Rescigno, ... The Journal of cell biology 155 (1), 53-64, 2001 | 348 | 2001 |
Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo DH Schuurhuis, A Ioan-Facsinay, B Nagelkerken, JJ van Schip, C Sedlik, ... The Journal of Immunology 168 (5), 2240-2246, 2002 | 318 | 2002 |
Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy M Mayoux, A Roller, V Pulko, S Sammicheli, S Chen, E Sum, C Jost, ... Science translational medicine 12 (534), eaav7431, 2020 | 293 | 2020 |
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses RA Rosalia, LJ Cruz, S van Duikeren, AT Tromp, AL Silva, W Jiskoot, ... Biomaterials 40, 88-97, 2015 | 292 | 2015 |
Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte–induced apoptosis: differential modulation by T helper type 1 and type … JP Medema, DH Schuurhuis, D Rea, J van Tongeren, J de Jong, SA Bres, ... The Journal of experimental medicine 194 (5), 657-668, 2001 | 266 | 2001 |
Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy MF Fransen, M Schoonderwoerd, P Knopf, MGM Camps, LJAC Hawinkels, ... JCI insight 3 (23), 2018 | 265 | 2018 |
Immature Dendritic Cells Acquire Cd8+Cytotoxic T Lymphocyte Priming Capacity upon Activation by T Helper Cell–Independent or–Dependent Stimuli DH Schuurhuis, S Laban, REM Toes, P Ricciardi-Castagnoli, ... The Journal of experimental medicine 192 (1), 145-150, 2000 | 262 | 2000 |
Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination G van Niel, R Wubbolts, T Ten Broeke, SI Buschow, FA Ossendorp, ... Immunity 25 (6), 885-894, 2006 | 250 | 2006 |
Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T‐cell activation RA Rosalia, ED Quakkelaar, A Redeker, S Khan, M Camps, JW Drijfhout, ... European journal of immunology 43 (10), 2554-2565, 2013 | 241 | 2013 |
Strategies for immunotherapy of cancer CJM Melief, REM Toes, JP Medema, SH Van Der Burg, F Ossendorp, ... Academic Press 75, 235-282, 2000 | 239 | 2000 |