The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins M Veldhoen, K Hirota, AM Westendorf, J Buer, L Dumoutier, JC Renauld, ... Nature 453 (7191), 106-109, 2008 | 1918 | 2008 |
Fate mapping of IL-17-producing T cells in inflammatory responses K Hirota, JH Duarte, M Veldhoen, E Hornsby, Y Li, DJ Cua, H Ahlfors, ... Nature immunology 12 (3), 255-263, 2011 | 1327 | 2011 |
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model K Hirota, H Yoshitomi, M Hashimoto, S Maeda, S Teradaira, N Sugimoto, ... The Journal of experimental medicine 204 (12), 2803-2812, 2007 | 1096 | 2007 |
Interleukin-17-producing γδ T cells selectively expand in response to pathogen products and environmental signals B Martin, K Hirota, DJ Cua, B Stockinger, M Veldhoen Immunity 31 (2), 321-330, 2009 | 1021 | 2009 |
Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells K Ko, S Yamazaki, K Nakamura, T Nishioka, K Hirota, T Yamaguchi, ... The Journal of experimental medicine 202 (7), 885-891, 2005 | 649 | 2005 |
Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells M Veldhoen, K Hirota, J Christensen, A O'Garra, B Stockinger Journal of Experimental Medicine 206 (1), 43-49, 2009 | 620 | 2009 |
T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis K Hirota, M Hashimoto, H Yoshitomi, S Tanaka, T Nomura, T Yamaguchi, ... The Journal of experimental medicine 204 (1), 41-47, 2007 | 583 | 2007 |
Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine Y Maeda, T Kurakawa, E Umemoto, D Motooka, Y Ito, K Gotoh, K Hirota, ... Arthritis & rheumatology 68 (11), 2646-2661, 2016 | 574 | 2016 |
Plasticity of TH17 cells in Peyer's patches is responsible for the induction of T cell–dependent IgA responses K Hirota, JE Turner, M Villa, JH Duarte, J Demengeot, OM Steinmetz, ... Nature immunology 14 (4), 372-379, 2013 | 534 | 2013 |
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation C Wilhelm, K Hirota, B Stieglitz, J Van Snick, M Tolaini, K Lahl, ... Nature immunology 12 (11), 1071-1077, 2011 | 534 | 2011 |
A role for fungal β-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice H Yoshitomi, N Sakaguchi, K Kobayashi, GD Brown, T Tagami, ... The Journal of experimental medicine 201 (6), 949-960, 2005 | 499 | 2005 |
Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis N Sugimoto, T Oida, K Hirota, K Nakamura, T Nomura, T Uchiyama, ... International immunology 18 (8), 1197-1209, 2006 | 466 | 2006 |
Control of immune responses by antigen-specific regulatory T cells expressing the folate receptor T Yamaguchi, K Hirota, K Nagahama, K Ohkawa, T Takahashi, T Nomura, ... Immunity 27 (1), 145-159, 2007 | 436 | 2007 |
The pathogenicity of Th17 cells in autoimmune diseases K Yasuda, Y Takeuchi, K Hirota Seminars in immunopathology 41 (3), 283-297, 2019 | 421 | 2019 |
Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions P Di Meglio, JH Duarte, H Ahlfors, NDL Owens, Y Li, F Villanova, I Tosi, ... Immunity 40 (6), 989-1001, 2014 | 351 | 2014 |
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment Y Kitagawa, N Ohkura, Y Kidani, A Vandenbon, K Hirota, R Kawakami, ... Nature immunology 18 (2), 173-183, 2017 | 348 | 2017 |
Complement drives Th17 cell differentiation and triggers autoimmune arthritis M Hashimoto, K Hirota, H Yoshitomi, S Maeda, S Teradaira, S Akizuki, ... Journal of Experimental Medicine 207 (6), 1135-1143, 2010 | 225 | 2010 |
External influences on the immune system via activation of the aryl hydrocarbon receptor B Stockinger, K Hirota, J Duarte, M Veldhoen Seminars in immunology 23 (2), 99-105, 2011 | 194 | 2011 |
Autoimmune Th17 cells induced synovial stromal and innate lymphoid cell secretion of the cytokine GM-CSF to initiate and augment autoimmune arthritis K Hirota, M Hashimoto, Y Ito, M Matsuura, H Ito, M Tanaka, H Watanabe, ... Immunity 48 (6), 1220-1232. e5, 2018 | 160 | 2018 |
Development, regulation and functional capacities of Th17 cells K Hirota, B Martin, M Veldhoen Seminars in immunopathology 32, 3-16, 2010 | 139 | 2010 |