Migration in confined 3D environments is determined by a combination of adhesiveness, nuclear volume, contractility, and cell stiffness LA Lautscham, C Kämmerer, JR Lange, T Kolb, C Mark, A Schilling, ... Biophysical journal 109 (5), 900-913, 2015 | 198 | 2015 |
Microconstriction arrays for high-throughput quantitative measurements of cell mechanical properties JR Lange, J Steinwachs, T Kolb, LA Lautscham, I Harder, G Whyte, ... Biophysical journal 109 (1), 26-34, 2015 | 160 | 2015 |
Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells T Kolb, K Maaß, M Hergt, U Aebi, H Herrmann Nucleus 2 (5), 425-433, 2011 | 124 | 2011 |
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors M Ratnaparkhe, JKL Wong, PC Wei, M Hlevnjak, T Kolb, M Simovic, ... Nature communications 9 (1), 4760, 2018 | 78 | 2018 |
Unbiased high-precision cell mechanical measurements with microconstrictions JR Lange, C Metzner, S Richter, W Schneider, M Spermann, T Kolb, ... Biophysical Journal 112 (7), 1472-1480, 2017 | 57 | 2017 |
Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis M Ratnaparkhe, M Hlevnjak, T Kolb, A Jauch, KK Maass, F Devens, ... Leukemia 31 (10), 2048-2056, 2017 | 55 | 2017 |
Induction of a massive endoplasmic reticulum and perinuclear space expansion by expression of lamin B receptor mutants and the related sterol reductases TM7SF2 and DHCR7 M Zwerger, T Kolb, K Richter, I Karakesisoglou, H Herrmann Molecular biology of the cell 21 (2), 354-368, 2010 | 55 | 2010 |
Optofluidic rotation of living cells for single‐cell tomography T Kolb, S Albert, M Haug, G Whyte Journal of biophotonics 8 (3), 239-246, 2015 | 41 | 2015 |
Dynamically reconfigurable fibre optical spanner T Kolb, S Albert, M Haug, G Whyte Lab on a Chip 14 (6), 1186-1190, 2014 | 26 | 2014 |
Developmental regulation of linkers of the nucleoskeleton to the cytoskeleton during mouse postnatal retinogenesis DS Razafsky Nucleus 4 (5), 399-409, 2013 | 26 | 2013 |
Single cell multi-omics analysis of chromothriptic medulloblastoma highlights genomic and transcriptomic consequences of genome instability RG Parra, MJ Przybilla, M Simovic, H Susak, M Ratnaparkhe, JKL Wong, ... bioRxiv, 2021.06. 25.449944, 2021 | 9 | 2021 |
Cell‐based model systems for genome instability: Dissecting the mechanistic basis of chromothripsis in cancer T Kolb, A Ernst International Journal of Cancer 149 (4), 754-759, 2021 | 8 | 2021 |
The age of adult pilocytic astrocytoma cells N Voronina, C Aichmüller, T Kolb, A Korshunov, M Ryzhova, ... Oncogene 40 (16), 2830-2841, 2021 | 8 | 2021 |
A synergistic interaction between HDAC‐and PARP inhibitors in childhood tumors with chromothripsis U Khalid, M Simovic, LA Hammann, M Iskar, JKL Wong, R Kumar, ... International Journal of Cancer 151 (4), 590-606, 2022 | 6 | 2022 |
Comparative parallel multi-omics analysis during the induction of pluripotent and trophectoderm states M Jaber, A Radwan, N Loyfer, M Abdeen, S Sebban, A Khatib, H Yassen, ... Nature Communications 13 (1), 3475, 2022 | 6 | 2022 |
A versatile system to introduce clusters of genomic double‐strand breaks in large cell populations T Kolb, U Khalid, M Simović, M Ratnaparkhe, J Wong, A Jauch, ... Genes, Chromosomes and Cancer 60 (5), 303-313, 2021 | 4 | 2021 |
Optomechanical measurement of the role of lamins in whole cell deformability T Kolb, J Kraxner, K Skodzek, M Haug, D Crawford, KK Maaß, KE Aifantis, ... Journal of Biophotonics 10 (12), 1657-1664, 2017 | 3 | 2017 |
Nuclear deformability is critically dependent on lamin A/B JR Lange, M Haug, T Kolb, S Albert, G Whyte, B Fabry Biophysical Journal 106 (2), 576a, 2014 | 3 | 2014 |
Optofluidic Single-Cell Rotation S Albert, T Kolb, M Haug, G Whyte Biophysical Journal 106 (2), 203a, 2014 | | 2014 |
High-resolution imaging of the nuclear envelope for investigation of the mechanical influence of the nucleus on cellular mechanics T Kolb, G Whyte Optical Trapping Applications, JT2A. 33, 2013 | | 2013 |