Wouter de Laat
Wouter de Laat
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Email confirmado em hubrecht.eu
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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
L Guelen, L Pagie, E Brasset, W Meuleman, MB Faza, W Talhout, ...
Nature 453 (7197), 948-951, 2008
16992008
Looping and interaction between hypersensitive sites in the active β-globin locus
B Tolhuis, RJ Palstra, E Splinter, F Grosveld, W de Laat
Molecular cell 10 (6), 1453-1465, 2002
15372002
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)
M Simonis, P Klous, E Splinter, Y Moshkin, R Willemsen, E De Wit, ...
Nature genetics 38 (11), 1348-1354, 2006
13782006
Molecular mechanism of nucleotide excision repair
WL de Laat, NGJ Jaspers, JHJ Hoeijmakers
Genes & development 13 (7), 768-785, 1999
13431999
CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus
E Splinter, H Heath, J Kooren, RJ Palstra, P Klous, F Grosveld, N Galjart, ...
Genes & development 20 (17), 2349-2354, 2006
7712006
A decade of 3C technologies: insights into nuclear organization
E De Wit, W De Laat
Genes & development 26 (1), 11-24, 2012
7622012
Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease
AM Sijbers, WL De Laat, RR Ariza, M Biggerstaff, YF Wei, JG Moggs, ...
Cell 86 (5), 811-822, 1996
6321996
The β-globin nuclear compartment in development and erythroid differentiation
RJ Palstra, B Tolhuis, E Splinter, R Nijmeijer, F Grosveld, W de Laat
Nature genetics 35 (2), 190-194, 2003
6292003
Quantitative analysis of chromosome conformation capture assays (3C-qPCR)
H Hagege, P Klous, C Braem, E Splinter, J Dekker, G Cathala, W De Laat, ...
Nature protocols 2 (7), 1722, 2007
6172007
A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia
S Gröschel, MA Sanders, R Hoogenboezem, E De Wit, BAM Bouwman, ...
Cell 157 (2), 369-381, 2014
4992014
A Regulatory Archipelago Controls Hox Genes Transcription in Digits
T Montavon, N Soshnikova, B Mascrez, E Joye, L Thevenet, E Splinter, ...
Cell 147 (5), 1132-1145, 2011
4622011
Topology of mammalian developmental enhancers and their regulatory landscapes
W De Laat, D Duboule
Nature 502 (7472), 499-506, 2013
4502013
eRNAs are required for p53-dependent enhancer activity and gene transcription
CA Melo, J Drost, PJ Wijchers, H van de Werken, E de Wit, JAFO Vrielink, ...
Molecular cell 49 (3), 524-535, 2013
4502013
Spatial organization of gene expression: the active chromatin hub
W de Laat, F Grosveld
Chromosome Research 11 (5), 447-459, 2003
4482003
The active spatial organization of the β-globin locus requires the transcription factor EKLF
R Drissen, RJ Palstra, N Gillemans, E Splinter, F Grosveld, S Philipsen, ...
Genes & development 18 (20), 2485-2490, 2004
4292004
CTCF binding polarity determines chromatin looping
E de Wit, ESM Vos, SJB Holwerda, C Valdes-Quezada, MJAM Verstegen, ...
Molecular cell 60 (4), 676-684, 2015
4232015
DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair
WL De Laat, E Appeldoorn, K Sugasawa, E Weterings, NGJ Jaspers, ...
Genes & development 12 (16), 2598-2609, 1998
4131998
The dynamic architecture of Hox gene clusters
D Noordermeer, M Leleu, E Splinter, J Rougemont, W De Laat, ...
Science 334 (6053), 222-225, 2011
3922011
An evaluation of 3C-based methods to capture DNA interactions
M Simonis, J Kooren, W De Laat
Nature methods 4 (11), 895-901, 2007
3612007
Robust 4C-seq data analysis to screen for regulatory DNA interactions
HJG Van De Werken, G Landan, SJB Holwerda, M Hoichman, P Klous, ...
Nature methods 9 (10), 969-972, 2012
3452012
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