Use of a scaffold peptide in the biosynthesis of amino acid–derived natural products CP Ting, MA Funk, SL Halaby, Z Zhang, T Gonen, WA Van Der Donk Science 365 (6450), 280-284, 2019 | 114 | 2019 |
Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase N Ando, EJ Brignole, CM Zimanyi, MA Funk, K Yokoyama, FJ Asturias, ... Proceedings of the National Academy of Sciences 108 (52), 21046-21051, 2011 | 106 | 2011 |
New tricks for the glycyl radical enzyme family LRF Backman, MA Funk, CD Dawson, CL Drennan Critical reviews in biochemistry and molecular biology 52 (6), 674-695, 2017 | 81 | 2017 |
Kinetics of conformational sampling in ubiquitin D Ban, M Funk, R Gulich, D Egger, TM Sabo, KFA Walter, RB Fenwick, ... Angewandte Chemie 123 (48), 11639-11642, 2011 | 80 | 2011 |
Ribosomal natural products, tailored to fit MA Funk, WA Van Der Donk Accounts of chemical research 50 (7), 1577-1586, 2017 | 75 | 2017 |
Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli CM Zimanyi, PYT Chen, G Kang, MA Funk, CL Drennan Elife 5, e07141, 2016 | 74 | 2016 |
Molecular basis of C–N bond cleavage by the glycyl radical enzyme choline trimethylamine-lyase S Bodea, MA Funk, EP Balskus, CL Drennan Cell chemical biology 23 (10), 1206-1216, 2016 | 62 | 2016 |
Structures of benzylsuccinate synthase elucidate roles of accessory subunits in glycyl radical enzyme activation and activity MA Funk, ET Judd, ENG Marsh, SJ Elliott, CL Drennan Proceedings of the National Academy of Sciences 111 (28), 10161-10166, 2014 | 55 | 2014 |
Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example PH Oyala, KR Ravichandran, MA Funk, PA Stucky, TA Stich, CL Drennan, ... Journal of the American Chemical Society 138 (25), 7951-7964, 2016 | 46 | 2016 |
Structure-guided identification of a small molecule that inhibits anaerobic choline metabolism by human gut bacteria M Orman, S Bodea, MA Funk, AM Campo, M Bollenbach, CL Drennan, ... Journal of the American Chemical Society 141 (1), 33-37, 2018 | 43 | 2018 |
Substrate-bound structures of benzylsuccinate synthase reveal how toluene is activated in anaerobic hydrocarbon degradation MA Funk, ENG Marsh, CL Drennan Journal of Biological Chemistry 290 (37), 22398-22408, 2015 | 38 | 2015 |
Structure and mechanism of ORF36, an amino sugar oxidizing enzyme in everninomicin biosynthesis JL Vey, A Al-Mestarihi, Y Hu, MA Funk, BO Bachmann, TM Iverson Biochemistry 49 (43), 9306-9317, 2010 | 38 | 2010 |
Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gαi Subunits, AM Preininger, MA Funk, WM Oldham, SM Meier, CA Johnston, ... Biochemistry 48 (12), 2630-2642, 2009 | 34 | 2009 |
The class III ribonucleotide reductase from Neisseria bacilliformis can utilize thioredoxin as a reductant Y Wei, MA Funk, LA Rosado, J Baek, CL Drennan, JA Stubbe Proceedings of the National Academy of Sciences 111 (36), E3756-E3765, 2014 | 31 | 2014 |
A cleaner, greener future for chemicals M Funk, C Ash Science 367 (6476), 378-379, 2020 | 15 | 2020 |
Disruption of an oligomeric interface prevents allosteric inhibition of Escherichia coli class Ia ribonucleotide reductase PYT Chen, MA Funk, EJ Brignole, CL Drennan Journal of Biological Chemistry 293 (26), 10404-10412, 2018 | 13 | 2018 |
In Other Journals C Ash, B Lopez, J Stajic, LB Ray, P Stern, MA Funk, HJ Smith Science 375 (6577), 156-157, 2022 | 12 | 2022 |
Transverse relaxation-optimized HCN experiment for tautomeric states of histidine sidechains H Schmidt, S Himmel, KFA Walter, V Klaukien, M Funk, D Lee Journal of the Korean Magnetic Resonance Society 12 (2), 89-95, 2008 | 5 | 2008 |
fHow ATP and dATP act as molecular switches to regulate enzymatic activity in the prototypic bacterial class Ia ribonucleotide reductase MA Funk, CM Zimanyi, GA Andree, AE Hamilos, CL Drennan bioRxiv, 2021.07. 31.454598, 2021 | 3 | 2021 |
Itaconate brings metalloenzyme to a halt MA Funk Science 366 (6465), 583-585, 2019 | 2 | 2019 |