Structural basis of homologous recombination ZX Sun S, McCorvie TJ, Yates LA Cellular and Molecular Life Sciences, 2019 | 117* | 2019 |
Isomerization of BRCA1–BARD1 promotes replication fork protection M Daza-Martin, K Starowicz, M Jamshad, S Tye, GE Ronson, HL MacKay, ... Nature 571 (7766), 521-527, 2019 | 105 | 2019 |
Structural basis for ligand-dependent dimerization of phenylalanine hydroxylase regulatory domain D Patel, J Kopec, F Fitzpatrick, TJ McCorvie, WW Yue Scientific reports 6 (1), 23748, 2016 | 72 | 2016 |
Structural basis of glycogen branching enzyme deficiency and pharmacologic rescue by rational peptide design DS Froese, A Michaeli, TJ McCorvie, T Krojer, M Sasi, E Melaev, ... Human molecular genetics 24 (20), 5667-5676, 2015 | 71 | 2015 |
Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase TJ McCorvie, J Kopec, AL Pey, F Fitzpatrick, D Patel, R Chalk, L Shrestha, ... Human Molecular Genetics 25 (11), 2234-2244, 2016 | 61 | 2016 |
Inter-domain communication of human cystathionine β-synthase: structural basis of S-adenosyl-L-methionine activation TJ McCorvie, J Kopec, SJ Hyung, F Fitzpatrick, X Feng, D Termine, ... Journal of Biological Chemistry 289 (52), 36018-36030, 2014 | 57 | 2014 |
Misfolding of galactose 1-phosphate uridylyltransferase can result in type I galactosemia TJ McCorvie, TJ Gleason, JL Fridovich-Keil, DJ Timson Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (8 …, 2013 | 54 | 2013 |
Structural insights into the MMACHC-MMADHC protein complex involved in vitamin B12 trafficking DS Froese, J Kopec, F Fitzpatrick, M Schuller, TJ McCorvie, R Chalk, ... Journal of Biological Chemistry 290 (49), 29167-29177, 2015 | 46 | 2015 |
Structural and molecular biology of type I galactosemia: Disease‐associated mutations TJ McCorvie, DJ Timson IUBMB life 63 (11), 949-954, 2011 | 39 | 2011 |
Altered cofactor binding affects stability and activity of human UDP-galactose 4′-epimerase: implications for type III galactosemia TJ McCorvie, Y Liu, A Frazer, TJ Gleason, JL Fridovich-Keil, DJ Timson Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (10 …, 2012 | 34 | 2012 |
The structural and molecular biology of type I galactosemia: Enzymology of galactose 1‐phosphate uridylyltransferase TJ McCorvie, DJ Timson IUBMB life 63 (9), 694-700, 2011 | 33 | 2011 |
Analysis of UDP‐galactose 4′‐epimerase mutations associated with the intermediate form of type III galactosaemia JS Chhay, CA Vargas, TJ McCorvie, JL Fridovich‐Keil, DJ Timson Journal of Inherited Metabolic Disease: Official Journal of the Society for …, 2008 | 28 | 2008 |
In silico prediction of the effects of mutations in the human UDP-galactose 4′-epimerase gene: towards a predictive framework for type III galactosemia TJ McCorvie, DJ Timson Gene 524 (2), 95-104, 2013 | 26 | 2013 |
In vivo and in vitro function of human UDP-galactose 4′-epimerase variants TJ McCorvie, J Wasilenko, Y Liu, JL Fridovich-Keil, DJ Timson Biochimie 93 (10), 1747-1754, 2011 | 22 | 2011 |
Galactosemia: Towards pharmacological chaperones S Banford, TJ McCorvie, AL Pey, DJ Timson Journal of Personalized Medicine 11 (2), 106, 2021 | 20 | 2021 |
Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism GA Bezerra, WR Foster, HJ Bailey, KG Hicks, SW Sauer, B Dimitrov, ... IUCrJ 7 (4), 693-706, 2020 | 20 | 2020 |
The Molecular Dynamics of Trypanosoma brucei UDP‐Galactose 4′‐Epimerase: A Drug Target for African Sleeping Sickness AJ Friedman, JD Durrant, LCT Pierce, TJ McCorvie, DJ Timson, ... Chemical biology & drug design 80 (2), 173-181, 2012 | 17 | 2012 |
Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate TJ McCorvie, PM Loria, M Tu, S Han, L Shrestha, DS Froese, IM Ferreira, ... Nature structural & molecular biology 29 (7), 628-638, 2022 | 12 | 2022 |
UDP-galactose 4-epimerase (GALE) T McCorvie, D Timson Handbook of glycosyltransferases and related genes, 2013 | 11 | 2013 |
The complex machinery of human cobalamin metabolism TJ McCorvie, D Ferreira, WW Yue, DS Froese Journal of Inherited Metabolic Disease 46 (3), 406-420, 2023 | 9 | 2023 |