Javier Gamo
TítuloCitado porAno
Thousands of chemical starting points for antimalarial lead identification
FJ Gamo, LM Sanz, J Vidal, C De Cozar, E Alvarez, JL Lavandera, ...
Nature 465 (7296), 305, 2010
8072010
Global transcriptional response of Bacillus subtilis to heat shock
JD Helmann, MFW Wu, PA Kobel, FJ Gamo, M Wilson, MM Morshedi, ...
Journal of Bacteriology 183 (24), 7318-7328, 2001
2832001
Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors …
JM Coteron, M Marco, J Esquivias, X Deng, KL White, J White, M Koltun, ...
Journal of medicinal chemistry 54 (15), 5540-5561, 2011
2112011
Fueling open‐source drug discovery: 177 small‐molecule leads against tuberculosis
L Ballell, RH Bates, RJ Young, D Alvarez‐Gomez, E Alvarez‐Ruiz, ...
ChemMedChem 8 (2), 313-321, 2013
2062013
A novel multiple-stage antimalarial agent that inhibits protein synthesis
B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ...
Nature 522 (7556), 315, 2015
1992015
Quinolone-3-diarylethers: a new class of antimalarial drug
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
Science translational medicine 5 (177), 177ra37-177ra37, 2013
1552013
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria
MA Phillips, J Lotharius, K Marsh, J White, A Dayan, KL White, ...
Science translational medicine 7 (296), 296ra111-296ra111, 2015
1472015
Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity
A Cameron, J Read, R Tranter, VJ Winter, RB Sessions, RL Brady, ...
Journal of Biological Chemistry 279 (30), 31429-31439, 2004
1422004
Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity
A Cameron, J Read, R Tranter, VJ Winter, RB Sessions, RL Brady, ...
Journal of Biological Chemistry 279 (30), 31429-31439, 2004
1422004
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium
MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ...
Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014
1342014
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
1232016
Global phenotypic screening for antimalarials
WA Guiguemde, AA Shelat, JF Garcia-Bustos, TT Diagana, FJ Gamo, ...
Chemistry & biology 19 (1), 116-129, 2012
1182012
P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action
LM Sanz, B Crespo, C De-Cózar, XC Ding, JL Llergo, JN Burrows, ...
PloS one 7 (2), e30949, 2012
1172012
Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series
JM Coterón, D Catterick, J Castro, MJ Chaparro, B Díaz, E Fernández, ...
Journal of medicinal chemistry 53 (16), 6129-6152, 2010
892010
Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug
FP da Cruz, C Martin, K Buchholz, MJ Lafuente-Monasterio, T Rodrigues, ...
Journal of Infectious Diseases 205 (8), 1278-1286, 2012
882012
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum
AB Vaidya, JM Morrisey, Z Zhang, S Das, TM Daly, TD Otto, NJ Spillman, ...
Nature communications 5, 5521, 2014
802014
An invitation to open innovation in malaria drug discovery: 47 quality starting points from the TCAMS
F Calderón, D Barros, JM Bueno, JM Coterón, E Fernández, FJ Gamo, ...
ACS medicinal chemistry letters 2 (10), 741-746, 2011
652011
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase
T Paquet, C Le Manach, DG Cabrera, Y Younis, PP Henrich, TS Abraham, ...
Science translational medicine 9 (387), eaad9735, 2017
632017
The mutation DGT1-1 decreases glucose transport and alleviates carbon catabolite repression in Saccharomyces cerevisiae.
FJ Gamo, MJ Lafuente, C Gancedo
Journal of bacteriology 176 (24), 7423-7429, 1994
631994
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV
B Dujon, K Albermann, M Aldea, D Alexandraki, W Ansorge, J Arino, ...
Nature 387 (6632 Suppl), 98-102, 1997
621997
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