Laura Orellana
Laura Orellana
Stockholm University
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Cited by
FlexServ: an integrated tool for the analysis of protein flexibility
J Camps, O Carrillo, A Emperador, L Orellana, A Hospital, M Rueda, ...
Bioinformatics 25 (13), 1709-1710, 2009
Correlated motions are a fundamental property of β-sheets
RB Fenwick, L Orellana, S Esteban-Martín, M Orozco, X Salvatella
Nature communications 5, 4070, 2014
Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development
ZA Binder, AH Thorne, S Bakas, EP Wileyto, M Bilello, H Akbari, ...
Cancer cell 34 (1), 163-177. e7, 2018
Approaching elastic network models to molecular dynamics flexibility
L Orellana, M Rueda, C Ferrer-Costa, JR Lopez-Blanco, P Chacón, ...
Journal of Chemical Theory and Computation, 2010
Erratum: Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair (Cancer Cell (2019) 35 (3)(504–518. e7 …
J Ma, JA Benitez, J Li, S Miki, CP de Albuquerque, T Galatro, L Orellana, ...
Cancer Cell 35 (5), 2019
Inhibition of nuclear PTEN tyrosine phosphorylation enhances glioma radiation sensitivity through attenuated DNA repair
J Ma, JA Benitez, J Li, S Miki, CP de Albuquerque, T Galatro, L Orellana, ...
Cancer cell 35 (3), 504-518. e7, 2019
Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations
L Orellana, O Yoluk, O Carrillo, M Orozco, E Lindahl
Nature communications 7, 12575, 2016
Finding Conformational Transition Pathways from Discrete Molecular Dynamics Simulations
P Sfriso, A Emperador, L Orellana, A Hospital, JL Gelpí, M Orozco
Journal of Chemical Theory and Computation, 0
Coarse-grained Representation of Protein Flexibility. Foundations, Successes, and Shortcomings.
M OROZCO, L ORELLANA, AN Naganathan, A Emperador, O Carrillo, ...
Computational Chemistry Methods in Structural Biology 85, 183, 2011
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope
L Orellana, AH Thorne, R Lema, J Gustavsson, AD Parisian, TN Cordeiro, ...
Proceedings of the National Academy of Sciences, 201821442, 2019
The molecular basis for sugar import in malaria parasites
DD Abdul Aziz Qureshi, Albert Suades, Rei Matsuoka, Joseph Brock, Sarah E ...
Nature, 2020
eBDIMS server: protein transition pathways with ensemble analysis in 2D-motion spaces
L Orellana, J Gustavsson, C Bergh, O Yoluk, E Lindahl
Bioinformatics, 2019
Large-scale conformational changes and protein function: breaking the in silico barrier
L Orellana
Frontiers in molecular biosciences 6, 117, 2019
Oncogenic mutations of the EGF-Receptor ectodomain reveal an unexpected mechanism for ligand-independent activation
L Orellana, A Hospital, M Orozco
biorXiv, 2014
Protein dynamics studied by coarse-grained and atomistic theoretical approaches
L Orellana
Universitat de Barcelona, 2014
Convergence of EGFR glioblastoma mutations: evolution and allostery rationalizing targeted therapy
L Orellana
Molecular & cellular oncology 6 (5), e1630798, 2019
understanding protein dynamics with coarsegrained models: from structures to disease: p25-3
L Orellana, M Orozco
The Febs Journal 279, 528, 2012
Understanding the Conformational Dynamics of a Pentameric Ligand-Gated Ion Channel through Markov State Modeling
CC Bergh, L Orellana, RJ Howard, E Lindahl
Biophysical Journal 116 (3), 395a-396a, 2019
Allosteric Modulation via Transmembrane Interfaces in a Pentameric Ligand-Gated Ion Channel
RJ Howard, Y Zhuang, S Nakamura, M Lycksell, H Kiik, U Rovšnik, ...
Biophysical Journal 116 (3), 245a-246a, 2019
The eBDIMS path-sampling server: generation, classification and interactive visualization of protein ensembles and transition pathways in 2D-motion space
L Orellana, J Gustavsson, C Bergh, O Yoluk, E Lindahl
arXiv preprint arXiv:1803.06873, 2018
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