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Jianxin Fu
Jianxin Fu
Soochow University
Email confirmado em omrf.org
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Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice
J Fu, B Wei, T Wen, MEV Johansson, X Liu, E Bradford, KA Thomsson, ...
The Journal of clinical investigation 121 (4), 1657-1666, 2011
3742011
Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2
BH Herzog, J Fu, SJ Wilson, PR Hess, A Sen, JM McDaniel, Y Pan, ...
Nature 502 (7469), 105-109, 2013
3492013
Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice
J Fu, H Gerhardt, JM McDaniel, B Xia, X Liu, L Ivanciu, A Ny, K Hermans, ...
The Journal of clinical investigation 118 (11), 3725-3737, 2008
2672008
The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture
JL Astarita, V Cremasco, J Fu, MC Darnell, JR Peck, JM Nieves-Bonilla, ...
Nature immunology 16 (1), 75-84, 2015
2662015
Platelets mediate lymphovenous hemostasis to maintain blood-lymphatic separation throughout life
PR Hess, DR Rawnsley, Z Jakus, Y Yang, DT Sweet, J Fu, B Herzog, ...
The Journal of clinical investigation 124 (1), 273-284, 2014
2352014
Lymph flow regulates collecting lymphatic vessel maturation in vivo
DT Sweet, JM Jiménez, J Chang, PR Hess, P Mericko-Ishizuka, J Fu, ...
The Journal of clinical investigation 125 (8), 2995-3007, 2015
1742015
Core 1–and 3–derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice
K Bergstrom, J Fu, MEV Johansson, X Liu, N Gao, Q Wu, J Song, ...
Mucosal immunology 10 (1), 91-103, 2017
1412017
Mechanotransduction activates canonical Wnt/β-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves
B Cha, X Geng, MR Mahamud, J Fu, A Mukherjee, Y Kim, E Jho, TH Kim, ...
Genes & development 30 (12), 1454-1469, 2016
1362016
Defective intestinal mucin-type O-glycosylation causes spontaneous colitis-associated cancer in mice
K Bergstrom, X Liu, Y Zhao, N Gao, Q Wu, K Song, Y Cui, Y Li, ...
Gastroenterology 151 (1), 152-164. e11, 2016
1312016
Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells
Y Li, J Fu, Y Ling, T Yago, JM McDaniel, J Song, X Bai, Y Kondo, Y Qin, ...
Proceedings of the National Academy of Sciences 114 (31), 8360-8365, 2017
1152017
Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3
WS Chen, Z Cao, S Sugaya, MJ Lopez, VG Sendra, N Laver, H Leffler, ...
Nature communications 7 (1), 11302, 2016
962016
Core 1-derived O-glycans are essential E-selectin ligands on neutrophils
T Yago, J Fu, JM McDaniel, JJ Miner, RP McEver, L Xia
Proceedings of the National Academy of Sciences 107 (20), 9204-9209, 2010
842010
Expression of survivin and its significance in colorectal cancer
WC Chen, Q Liu, JX Fu, SY Kang
World Journal of Gastroenterology: WJG 10 (19), 2886, 2004
782004
Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis
J Yi, K Bergstrom, J Fu, X Shan, JM McDaniel, S McGee, D Qu, ...
Cell Death & Differentiation 26 (9), 1656-1669, 2019
722019
Disruption of C1galt1 gene promotes development and metastasis of pancreatic adenocarcinomas in mice
S Chugh, S Barkeer, S Rachagani, RK Nimmakayala, N Perumal, ...
Gastroenterology 155 (5), 1608-1624, 2018
692018
Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma
K Song, BH Herzog, M Sheng, J Fu, JM McDaniel, J Ruan, L Xia
Cancer research 73 (24), 7254-7264, 2013
672013
O-glycans direct selectin ligands to lipid rafts on leukocytes
B Shao, T Yago, H Setiadi, Y Wang, P Mehta-D’souza, J Fu, PR Crocker, ...
Proceedings of the National Academy of Sciences 112 (28), 8661-8666, 2015
562015
Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets
Y Pan, T Yago, J Fu, B Herzog, JM McDaniel, P Mehta-D’Souza, X Cai, ...
Blood, The Journal of the American Society of Hematology 124 (24), 3656-3665, 2014
552014
Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking
Y Kondo, J Fu, H Wang, C Hoover, JM McDaniel, R Steet, D Patra, J Song, ...
JCI insight 3 (14), 2018
522018
Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis
PDA Perez-Muñoz ME, Bergstrom K, Peng V, Schmaltz R, Jimenez-Cardona R ...
Gut Microbes. 5 (3), 286-295, 2014
462014
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