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John W. Rumsey, Ph.D.
John W. Rumsey, Ph.D.
Javelin Biotech, Inc.
Email confirmado em javelinbio.com - Página inicial
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Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity
C Zechner, L Lai, JF Zechner, T Geng, Z Yan, JW Rumsey, D Collia, ...
Cell metabolism 12 (6), 633-642, 2010
2902010
Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism
Z Gan, J Rumsey, BC Hazen, L Lai, TC Leone, RB Vega, H Xie, ...
The Journal of clinical investigation 123 (6), 2564-2575, 2013
2112013
Embryonic motoneuron-skeletal muscle co-culture in a defined system
M Das, JW Rumsey, CA Gregory, N Bhargava, JF Kang, P Molnar, ...
Neuroscience 146 (2), 481-488, 2007
1302007
A defined long-term in vitro tissue engineered model of neuromuscular junctions
M Das, JW Rumsey, N Bhargava, M Stancescu, JJ Hickman
Biomaterials 31 (18), 4880-4888, 2010
1252010
Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics
CW McAleer, CJ Long, D Elbrecht, T Sasserath, LR Bridges, JW Rumsey, ...
Science translational medicine 11 (497), eaav1386, 2019
1212019
Neuromuscular junction formation between human stem-cell-derived motoneurons and rat skeletal muscle in a defined system
X Guo, M Das, J Rumsey, M Gonzalez, M Stancescu, J Hickman
Tissue Engineering Part C: Methods 16 (6), 1347-1355, 2010
1082010
Photolithographic patterning of C2C12 myotubes using vitronectin as growth substrate in serum‐free medium
P Molnar, W Wang, A Natarajan, JW Rumsey, JJ Hickman
Biotechnology progress 23 (1), 265-268, 2007
1042007
Skeletal muscle tissue engineering: a maturation model promoting long-term survival of myotubes, structural development of the excitation–contraction coupling apparatus and …
M Das, JW Rumsey, N Bhargava, M Stancescu, JJ Hickman
Biomaterials 30 (29), 5392-5402, 2009
722009
Tissue engineering the mechanosensory circuit of the stretch reflex arc: sensory neuron innervation of intrafusal muscle fibers
JW Rumsey, M Das, A Bhalkikar, M Stancescu, JJ Hickman
Biomaterials 31 (32), 8218-8227, 2010
632010
Differential monocyte actuation in a three‐organ functional innate immune system‐on‐a‐chip
T Sasserath, JW Rumsey, CW McAleer, LR Bridges, CJ Long, D Elbrecht, ...
Advanced science 7 (13), 2000323, 2020
572020
Developing a novel serum-free cell culture model of skeletal muscle differentiation by systematically studying the role of different growth factors in myotube formation
M Das, JW Rumsey, N Bhargava, C Gregory, L Riedel, JF Kang, ...
In Vitro Cellular & Developmental Biology-Animal 45, 378-387, 2009
482009
Node of Ranvier formation on motoneurons in vitro
JW Rumsey, M Das, M Stancescu, M Bott, C Fernandez-Valle, JJ Hickman
Biomaterials 30 (21), 3567-3572, 2009
472009
Direct patterning of coplanar polyethylene glycol alkylsilane monolayers by deep-ultraviolet photolithography as a general method for high fidelity, long-term cell patterning …
K Wilson, M Stancescu, M Das, J Rumsey, J Hickman
Journal of Vacuum Science & Technology B 29 (2), 2011
432011
Tissue engineering intrafusal fibers: Dose-and time-dependent differentiation of nuclear bag fibers in a defined in vitro system using neuregulin 1-β-1
JW Rumsey, M Das, JF Kang, R Wagner, P Molnar, JJ Hickman
Biomaterials 29 (8), 994-1004, 2008
412008
Inhibition of phagosome maturation and survival of Mycobacterium avium subspecies paratuberculosis in polymorphonuclear leukocytes from Crohn’s disease patients
JW Rumsey1ABCDEF, JF Valentine2ABCDEF, SA Naser1ABCDEFG
Med Sci Monit 12 (4), 139, 2006
402006
Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation
VL Slaughter, JW Rumsey, R Boone, D Malik, Y Cai, NN Sriram, CJ Long, ...
Scientific Reports 11 (1), 13159, 2021
362021
A human-on-a-chip approach to tackling rare diseases
CPP de Mello, J Rumsey, V Slaughter, JJ Hickman
Drug discovery today 24 (11), 2139-2151, 2019
362019
A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders
K Autar, X Guo, JW Rumsey, CJ Long, N Akanda, M Jackson, ...
Stem Cell Reports 17 (1), 96-109, 2022
332022
Electrophysiological and immunocytochemical characterization of DRG neurons on an organosilane surface in serum-free medium
J Liu, JW Rumsey, M Das, P Molnar, C Gregory, L Riedel, JJ Hickman
In Vitro Cellular & Developmental Biology-Animal 44, 162-168, 2008
312008
Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression
A Badu-Mensah, X Guo, CW McAleer, JW Rumsey, JJ Hickman
Scientific reports 10 (1), 14302, 2020
262020
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