Sascha Rutz
Sascha Rutz
Genentech, Department of Cancer Immunology
Verified email at
Cited by
Cited by
Regulation and functions of the IL-10 family of cytokines in inflammation and disease
W Ouyang, S Rutz, NK Crellin, PA Valdez, SG Hymowitz
Annual review of immunology 29, 71-109, 2011
Interleukin‐2 is essential for CD4+CD25+ regulatory T cell function
M De La Rosa, S Rutz, H Dorninger, A Scheffold
European journal of immunology 34 (9), 2480-2488, 2004
IL‐22, not simply a Th17 cytokine
S Rutz, C Eidenschenk, W Ouyang
Immunological reviews 252 (1), 116-132, 2013
A genomic regulatory element that directs assembly and function of immune-specific AP-1–IRF complexes
E Glasmacher, S Agrawal, AB Chang, TL Murphy, W Zeng, B Vander Lugt, ...
Science 338 (6109), 975-980, 2012
The IL-20 subfamily of cytokines—from host defence to tissue homeostasis
S Rutz, X Wang, W Ouyang
Nature reviews Immunology 14 (12), 783-795, 2014
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH 17 cells
S Rutz, R Noubade, C Eidenschenk, N Ota, W Zeng, Y Zheng, J Hackney, ...
Nature immunology 12 (12), 1238-1245, 2011
Design of siRNAs producing unstructured guide-RNAs results in improved RNA interference efficiency
V Patzel, S Rutz, I Dietrich, C Köberle, A Scheffold, SHE Kaufmann
Nature biotechnology 23 (11), 1440-1444, 2005
NRROS negatively regulates reactive oxygen species during host defence and autoimmunity
R Noubade, K Wong, N Ota, S Rutz, C Eidenschenk, PA Valdez, J Ding, ...
Nature 509 (7499), 235-239, 2014
Notch regulates IL-10 production by T helper 1 cells
S Rutz, M Janke, N Kassner, T Hohnstein, M Krueger, A Scheffold
Proceedings of the National Academy of Sciences 105 (9), 3497-3502, 2008
Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection
M Muñoz, C Eidenschenk, N Ota, K Wong, U Lohmann, AA Kühl, X Wang, ...
Immunity 42 (2), 321-331, 2015
Role of Blimp-1 in programing Th effector cells into IL-10 producers
C Neumann, F Heinrich, K Neumann, V Junghans, MF Mashreghi, ...
Journal of Experimental Medicine 211 (9), 1807-1819, 2014
Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells
A Seki, S Rutz
Journal of Experimental Medicine 215 (3), 985-997, 2018
Regulation of epithelial immunity by IL-17 family cytokines
R Pappu, S Rutz, W Ouyang
Trends in immunology 33 (7), 343-349, 2012
Autoregulation of Th1-mediated inflammation by twist1
U Niesner, I Albrecht, M Janke, C Doebis, C Loddenkemper, MH Lexberg, ...
The Journal of experimental medicine 205 (8), 1889-1901, 2008
Notch ligands Delta‐like1, Delta‐like4 and Jagged1 differentially regulate activation of peripheral T helper cells
S Rutz, B Mordmüller, S Sakano, A Scheffold
European journal of immunology 35 (8), 2443-2451, 2005
Cutting edge: Plasmacytoid dendritic cells induce IL-10 production in T cells via the Delta-like-4/Notch axis
N Kassner, M Krueger, H Yagita, A Dzionek, A Hutloff, R Kroczek, ...
The journal of immunology 184 (2), 550-554, 2010
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
S Rutz, N Kayagaki, QT Phung, C Eidenschenk, R Noubade, X Wang, ...
Nature 518 (7539), 417-421, 2015
Role of IL-22 in microbial host defense
C Eidenschenk, S Rutz, O Liesenfeld, W Ouyang
Interleukin-10 in Health and Disease, 213-236, 2014
Regulation of interleukin-10 and interleukin-22 expression in T helper cells
S Rutz, W Ouyang
Current opinion in immunology 23 (5), 605-612, 2011
siRNA stabilization prolongs gene knockdown in primary T lymphocytes
A Mantei, S Rutz, M Janke, D Kirchhoff, U Jung, V Patzel, U Vogel, ...
European journal of immunology 38 (9), 2616-2625, 2008
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