| Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice RA Cherny, CS Atwood, ME Xilinas, DN Gray, WD Jones, CA McLean, ... Neuron 30 (3), 665-676, 2001 | 1836 | 2001 |
| The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction X Huang, CS Atwood, MA Hartshorn, G Multhaup, LE Goldstein, ... Biochemistry 38 (24), 7609-7616, 1999 | 1418 | 1999 |
| Dramatic aggregation of Alzheimer Aβ by Cu (II) is induced by conditions representing physiological acidosis CS Atwood, RD Moir, X Huang, RC Scarpa, NME Bacarra, DM Romano, ... Journal of Biological Chemistry 273 (21), 12817-12826, 1998 | 1317 | 1998 |
| Cu (II) potentiation of Alzheimer Aβ neurotoxicity: correlation with cell-free hydrogen peroxide production and metal reduction X Huang, MP Cuajungco, CS Atwood, MA Hartshorn, JDA Tyndall, ... Journal of Biological Chemistry 274 (52), 37111-37116, 1999 | 1002 | 1999 |
| Characterization of copper interactions with Alzheimer amyloid β peptides: identification of an attomolar‐affinity copper binding site on amyloid β1‐42 CS Atwood, RC Scarpa, X Huang, RD Moir, WD Jones, DP Fairlie, ... Journal of neurochemistry 75 (3), 1219-1233, 2000 | 823 | 2000 |
| Metalloenzyme-like activity of Alzheimer's disease β-amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2 C Opazo, X Huang, RA Cherny, RD Moir, AE Roher, AR White, R Cappai, ... Journal of Biological Chemistry 277 (43), 40302-40308, 2002 | 778 | 2002 |
| Aqueous dissolution of Alzheimer's disease Aβ amyloid deposits by biometal depletion RA Cherny, JT Legg, CA McLean, DP Fairlie, X Huang, CS Atwood, ... Journal of Biological Chemistry 274 (33), 23223-23228, 1999 | 664 | 1999 |
| An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript JT Rogers, JD Randall, CM Cahill, PS Eder, X Huang, H Gunshin, L Leiter, ... Journal of Biological Chemistry 277 (47), 45518-45528, 2002 | 653 | 2002 |
| Cytosolic β-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease LE Goldstein, JA Muffat, RA Cherny, RD Moir, MH Ericsson, X Huang, ... The Lancet 361 (9365), 1258-1265, 2003 | 586 | 2003 |
| Evidence that the β-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of Aβ by zinc MP Cuajungco, LE Goldstein, A Nunomura, MA Smith, JT Lim, CS Atwood, ... Journal of Biological Chemistry 275 (26), 19439-19442, 2000 | 555 | 2000 |
| Redox‐active metals, oxidative stress, and Alzheimer's disease pathology X Huang, RD Moir, RE Tanzi, AI Bush, JT Rogers Annals of the New York Academy of Sciences 1012 (1), 153-163, 2004 | 527 | 2004 |
| Copper mediates dityrosine cross-linking of Alzheimer's amyloid-β CS Atwood, G Perry, H Zeng, Y Kato, WD Jones, KQ Ling, X Huang, ... Biochemistry 43 (2), 560-568, 2004 | 456 | 2004 |
| Zinc-induced Alzheimer's Aβ1–40 aggregation is mediated by conformational factors X Huang, CS Atwood, RD Moir, MA Hartshorn, JP Vonsattel, RE Tanzi, ... Journal of Biological Chemistry 272 (42), 26464-26470, 1997 | 424 | 1997 |
| N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer’s disease, vascular dementia and Parkinson’s disease D Olivares, V K Deshpande, Y Shi, D K Lahiri, N H Greig, J T Rogers, ... Current Alzheimer Research 9 (6), 746-758, 2012 | 407 | 2012 |
| Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106− 126 MF Jobling, X Huang, LR Stewart, KJ Barnham, C Curtain, I Volitakis, ... Biochemistry 40 (27), 8073-8084, 2001 | 326 | 2001 |
| Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer’s Aβ peptides X Huang, CS Atwood, RD Moir, MA Hartshorn, RE Tanzi, AI Bush JBIC Journal of Biological Inorganic Chemistry 9, 954-960, 2004 | 325 | 2004 |
| Homocysteine potentiates copper‐and amyloid beta peptide‐mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's‐type neurodegenerative pathways AR White, X Huang, MF Jobling, CJ Barrow, K Beyreuther, CL Masters, ... Journal of neurochemistry 76 (5), 1509-1520, 2001 | 318 | 2001 |
| Role of free radicals and metal ions in the pathogenesis of Alzheimer’s disease CS Atwood, X Huang, RD Moir, RE Tanzi, AI Bush Metal ions in biological systems, 309-364, 2018 | 279 | 2018 |
| Metal chelation as a potential therapy for Alzheimer's disease MP Cuajungco, KY Faget, X Huang, RE Tanzi, AI Bush Annals of the New York Academy of Sciences 920 (1), 292-304, 2000 | 276 | 2000 |
| 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote α-crystallin cross-linking by metal ion reduction LE Goldstein, MC Leopold, X Huang, CS Atwood, AJ Saunders, ... Biochemistry 39 (24), 7266-7275, 2000 | 242 | 2000 |
