Engineered immunogen binding to alum adjuvant enhances humoral immunity TJ Moyer, Y Kato, W Abraham, JYH Chang, DW Kulp, N Watson, ... Nature Medicine 26 (3), 430-440, 2020 | 202 | 2020 |
Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity Y Agarwal, LE Milling, JYH Chang, L Santollani, A Sheen, EA Lutz, ... Nature biomedical engineering 6 (2), 129-143, 2022 | 71 | 2022 |
High-performance chemical-and light-inducible recombinases in mammalian cells and mice BH Weinberg, JH Cho, Y Agarwal, NTH Pham, LD Caraballo, M Walkosz, ... Nature communications 10 (1), 4845, 2019 | 51 | 2019 |
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains KS Gordon, T Kyung, CR Perez, PV Holec, A Ramos, AQ Zhang, ... Nature biomedical engineering 6 (7), 855-866, 2022 | 27 | 2022 |
Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade C Wang, A Cui, M Bukenya, A Aung, D Pradhan, CA Whittaker, Y Agarwal, ... Cell reports 37 (8), 2021 | 24 | 2021 |
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies EA Lutz, Y Agarwal, N Momin, SC Cowles, JR Palmeri, E Duong, V Hornet, ... Proceedings of the National Academy of Sciences 119 (36), e2205983119, 2022 | 18 | 2022 |
Neoadjuvant STING activation, extended half-life IL2, and checkpoint blockade promote metastasis clearance via sustained NK-cell activation LE Milling, D Garafola, Y Agarwal, S Wu, A Thomas, N Donahue, J Adams, ... Cancer immunology research 10 (1), 26-39, 2022 | 12 | 2022 |
Tumor-localized catalases can fail to alter tumor growth and transcriptional profiles in subcutaneous syngeneic mouse tumor models A Sheen, Y Agarwal, KM Cheah, SC Cowles, JA Stinson, JR Palmeri, ... Redox Biology 64, 102766, 2023 | 5 | 2023 |
Co‐anchoring of engineered immunogen and immunostimulatory cytokines to alum promotes enhanced‐humoral immunity JYH Chang, Y Agarwal, KA Rodrigues, N Momin, K Ni, BJ Read, TJ Moyer, ... Advanced Therapeutics 5 (7), 2100235, 2022 | 3 | 2022 |
Optimization of an alum-anchored clinical HIV vaccine candidate KA Rodrigues, CA Cottrell, JM Steichen, B Groschel, W Abraham, H Suh, ... npj Vaccines 8 (1), 117, 2023 | 1 | 2023 |
Reprogramming brain immunosurveillance with engineered cytokines A Tabet, Y Agarwal, J Stinson, C Apra, V Will, M Manthey, N Momin, ... bioRxiv, 2022.06. 21.497082, 2022 | 1 | 2022 |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof DJ Irvine, KD Wittrup, T Moyer, Y Agarwal US Patent 11,642,409, 2023 | | 2023 |
738 Intratumoral administration of alum-tethered engineered inflammatory cytokines safely elicits potent local and systemic immunity Y Agarwal, K Wittrup, D Irvine Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |
BBF RFC 94: Type IIS Assembly for Bacterial Transcriptional Units: A Standardized Assembly Method for Building Bacterial Transcriptional Units Using the Type IIS Restriction … TL Haddock, DM Densmore, E Appleton, S Carr, S Iverson, M De Freitas, ... | | 2015 |
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies | | |
Genetic Systems Engineering P Vaidyanathan, E Appleton, C Madsen, CI Vasile, A Pacheco, I Haghighi, ... | | |