Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy X Lan, DJ Jörg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ... Nature 549 (7671), 227-232, 2017 | 426 | 2017 |
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis D Karunakaran, M Geoffrion, L Wei, W Gan, L Richards, P Shangari, ... Science advances 2 (7), e1600224, 2016 | 246 | 2016 |
Gradient of developmental and injury response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity LM Richards, OKN Whitley, G MacLeod, FMG Cavalli, FJ Coutinho, ... Nature Cancer 2 (2), 157-173, 2021 | 183 | 2021 |
Macrophage mitochondrial energy status regulates cholesterol efflux and is enhanced by anti-miR33 in atherosclerosis D Karunakaran, AB Thrush, MA Nguyen, L Richards, M Geoffrion, ... Circulation research 117 (3), 266-278, 2015 | 176 | 2015 |
PRMT5 inhibition disrupts splicing and stemness in glioblastoma P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, ... Nature communications 12 (1), 979, 2021 | 87 | 2021 |
Therapeutic inhibition of miR-33 promotes fatty acid oxidation but does not ameliorate metabolic dysfunction in diet-induced obesity D Karunakaran, L Richards, M Geoffrion, D Barrette, RJ Gotfrit, ME Harper, ... Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2536-2543, 2015 | 73 | 2015 |
Wnt activation as a therapeutic strategy in medulloblastoma B Manoranjan, C Venugopal, D Bakhshinyan, AA Adile, L Richards, ... Nature Communications 11 (1), 4323, 2020 | 42 | 2020 |
Toxicological evaluation of representative silver nanoparticles in macrophages and epithelial cells KC Nguyen, L Richards, A Massarsky, TW Moon, AF Tayabali Toxicology in Vitro 33, 163-173, 2016 | 38 | 2016 |
CReSCENT: cancer single cell expression toolkit S Mohanraj, JJ Díaz-Mejía, MD Pham, H Elrick, M Husić, S Rashid, P Luo, ... Nucleic Acids Research 48 (W1), W372-W379, 2020 | 22 | 2020 |
Longitudinal single-cell analysis of a myeloma mouse model identifies subclonal molecular programs associated with progression DC Croucher, LM Richards, SP Tsofack, D Waller, Z Li, EN Wei, ... Nature communications 12 (1), 6322, 2021 | 19 | 2021 |
A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours AA Hamed, DJ Kunz, I El-Hamamy, QM Trinh, OD Subedar, LM Richards, ... Nature Communications 13 (1), 4178, 2022 | 16 | 2022 |
Brain tumor stem cell dependence on glutaminase reveals a metabolic vulnerability through the amino acid deprivation response pathway IJ Restall, O Cseh, LM Richards, TJ Pugh, HA Luchman, S Weiss Cancer Research 80 (24), 5478-5490, 2020 | 15 | 2020 |
The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells M Pryszlak, M Wiggans, X Chen, JE Jaramillo, SE Burns, LM Richards, ... Cell reports 34 (13), 2021 | 12 | 2021 |
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis. Sci Adv 2016; 2 (7): e1600224 D Karunakaran, M Geoffrion, L Wei, W Gan, L Richards, P Shangari, ... Go to original source... Go to PubMed, 0 | 11 | |
A comparison of data integration methods for single-cell RNA sequencing of cancer samples LM Richards, M Riverin, S Mohanraj, S Ayyadhury, DC Croucher, ... bioRxiv, 2021.08. 04.453579, 2021 | 7 | 2021 |
Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma MA Qazi, SK Salim, KR Brown, N Mickolajewicz, N Savage, H Han, ... Cell Reports, 2022 | 4 | 2022 |
Single-cell transcriptional analysis of the immune tumour microenvironment during myeloma disease evolution DC Croucher, LM Richards, D Waller, Z Li, XF Huang, M Chesi, ... bioRxiv, 2021.10. 22.464971, 2021 | 1 | 2021 |
PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites M ALQAZZAZ, FE Ciamponi Sr, JC Ho, MI Maron, M Yadav, AM Sababi, ... bioRxiv, 2024.03. 14.584861, 2024 | | 2024 |
Selective Cell State in the Clonally Expanded T-Cell Compartment of Vκ* MYC Mice Responding to Treatment with Checkpoint Inhibitors DC Croucher, LM Richards, Z Li, E nong Wei, XF Huang, D Waller, ... Blood 138, 1581, 2021 | | 2021 |
Dissecting Genetic and Cellular Heterogeneity in Glioblastoma at Single Cell Resolution LM Richards University of Toronto (Canada), 2021 | | 2021 |