Seguir
Laura M. Richards
Laura M. Richards
Celsius Therapeutics
Email confirmado em mail.utoronto.ca
Título
Citado por
Citado por
Ano
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy
X Lan, DJ Jörg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ...
Nature 549 (7671), 227-232, 2017
4262017
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis
D Karunakaran, M Geoffrion, L Wei, W Gan, L Richards, P Shangari, ...
Science advances 2 (7), e1600224, 2016
2462016
Gradient of developmental and injury response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity
LM Richards, OKN Whitley, G MacLeod, FMG Cavalli, FJ Coutinho, ...
Nature Cancer 2 (2), 157-173, 2021
1832021
Macrophage mitochondrial energy status regulates cholesterol efflux and is enhanced by anti-miR33 in atherosclerosis
D Karunakaran, AB Thrush, MA Nguyen, L Richards, M Geoffrion, ...
Circulation research 117 (3), 266-278, 2015
1762015
PRMT5 inhibition disrupts splicing and stemness in glioblastoma
P Sachamitr, JC Ho, FE Ciamponi, W Ba-Alawi, FJ Coutinho, ...
Nature communications 12 (1), 979, 2021
872021
Therapeutic inhibition of miR-33 promotes fatty acid oxidation but does not ameliorate metabolic dysfunction in diet-induced obesity
D Karunakaran, L Richards, M Geoffrion, D Barrette, RJ Gotfrit, ME Harper, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (12), 2536-2543, 2015
732015
Wnt activation as a therapeutic strategy in medulloblastoma
B Manoranjan, C Venugopal, D Bakhshinyan, AA Adile, L Richards, ...
Nature Communications 11 (1), 4323, 2020
422020
Toxicological evaluation of representative silver nanoparticles in macrophages and epithelial cells
KC Nguyen, L Richards, A Massarsky, TW Moon, AF Tayabali
Toxicology in Vitro 33, 163-173, 2016
382016
CReSCENT: cancer single cell expression toolkit
S Mohanraj, JJ Díaz-Mejía, MD Pham, H Elrick, M Husić, S Rashid, P Luo, ...
Nucleic Acids Research 48 (W1), W372-W379, 2020
222020
Longitudinal single-cell analysis of a myeloma mouse model identifies subclonal molecular programs associated with progression
DC Croucher, LM Richards, SP Tsofack, D Waller, Z Li, EN Wei, ...
Nature communications 12 (1), 6322, 2021
192021
A brain precursor atlas reveals the acquisition of developmental-like states in adult cerebral tumours
AA Hamed, DJ Kunz, I El-Hamamy, QM Trinh, OD Subedar, LM Richards, ...
Nature Communications 13 (1), 4178, 2022
162022
Brain tumor stem cell dependence on glutaminase reveals a metabolic vulnerability through the amino acid deprivation response pathway
IJ Restall, O Cseh, LM Richards, TJ Pugh, HA Luchman, S Weiss
Cancer Research 80 (24), 5478-5490, 2020
152020
The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells
M Pryszlak, M Wiggans, X Chen, JE Jaramillo, SE Burns, LM Richards, ...
Cell reports 34 (13), 2021
122021
Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis. Sci Adv 2016; 2 (7): e1600224
D Karunakaran, M Geoffrion, L Wei, W Gan, L Richards, P Shangari, ...
Go to original source... Go to PubMed, 0
11
A comparison of data integration methods for single-cell RNA sequencing of cancer samples
LM Richards, M Riverin, S Mohanraj, S Ayyadhury, DC Croucher, ...
bioRxiv, 2021.08. 04.453579, 2021
72021
Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma
MA Qazi, SK Salim, KR Brown, N Mickolajewicz, N Savage, H Han, ...
Cell Reports, 2022
42022
Single-cell transcriptional analysis of the immune tumour microenvironment during myeloma disease evolution
DC Croucher, LM Richards, D Waller, Z Li, XF Huang, M Chesi, ...
bioRxiv, 2021.10. 22.464971, 2021
12021
PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites
M ALQAZZAZ, FE Ciamponi Sr, JC Ho, MI Maron, M Yadav, AM Sababi, ...
bioRxiv, 2024.03. 14.584861, 2024
2024
Selective Cell State in the Clonally Expanded T-Cell Compartment of Vκ* MYC Mice Responding to Treatment with Checkpoint Inhibitors
DC Croucher, LM Richards, Z Li, E nong Wei, XF Huang, D Waller, ...
Blood 138, 1581, 2021
2021
Dissecting Genetic and Cellular Heterogeneity in Glioblastoma at Single Cell Resolution
LM Richards
University of Toronto (Canada), 2021
2021
O sistema não pode efectuar a operação agora. Tente mais tarde.
Artigos 1–20