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Arne Raasakka
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Antagonistic functions of MBP and CNP establish cytosolic channels in CNS myelin
N Snaidero, C Velte, M Myllykoski, A Raasakka, A Ignatev, HB Werner, ...
Cell reports 18 (2), 314-323, 2017
1882017
Membrane association landscape of myelin basic protein portrays formation of the myelin major dense line
A Raasakka, S Ruskamo, J Kowal, R Barker, A Baumann, A Martel, ...
Scientific reports 7 (1), 1-18, 2017
762017
The myelin membrane-associated enzyme 2′, 3′-cyclic nucleotide 3′-phosphodiesterase: on a highway to structure and function
A Raasakka, P Kursula
Neuroscience bulletin 30 (6), 956-966, 2014
632014
Molecular structure and function of myelin protein P0 in membrane stacking
A Raasakka, S Ruskamo, J Kowal, H Han, A Baumann, M Myllykoski, ...
Scientific reports 9 (1), 1-15, 2019
492019
Myelin 2′, 3′-cyclic nucleotide 3′-phosphodiesterase: active-site ligand binding and molecular conformation
M Myllykoski, A Raasakka, H Han, P Kursula
PloS one 7 (2), e32336, 2012
422012
Structural and functional evolution of 2′, 3′-cyclic nucleotide 3′-phosphodiesterase
M Myllykoski, L Seidel, G Muruganandam, A Raasakka, AE Torda, ...
Brain research 1641, 64-78, 2016
382016
Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2
S Ruskamo, T Nieminen, CK Kristiansen, GH Vatne, A Baumann, EI Hallin, ...
Scientific reports 7 (1), 1-13, 2017
332017
Determinants of ligand binding and catalytic activity in the myelin enzyme 2′, 3′-cyclic nucleotide 3′-phosphodiesterase
A Raasakka, M Myllykoski, S Laulumaa, M Lehtimäki, M Härtlein, ...
Scientific reports 5 (1), 1-15, 2015
252015
How Does Protein Zero Assemble Compact Myelin?
A Raasakka, P Kursula
Cells 9 (8), 1832, 2020
222020
Flexible Players within the Sheaths: The Intrinsically Disordered Proteins of Myelin in Health and Disease
A Raasakka, P Kursula
Cells 9 (2), 470, 2020
222020
Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the β barrel in fatty acid binding proteins
S Laulumaa, T Nieminen, A Raasakka, OC Krokengen, A Safaryan, ...
BMC structural biology 18 (1), 1-13, 2018
212018
Crystallographic analysis of the reaction cycle of 2′, 3′-cyclic nucleotide 3′-phosphodiesterase, a unique member of the 2H phosphoesterase family
M Myllykoski, A Raasakka, M Lehtimäki, H Han, I Kursula, P Kursula
Journal of molecular biology 425 (22), 4307-4322, 2013
182013
Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice
S Ruskamo, OC Krokengen, J Kowal, T Nieminen, M Lehtimäki, ...
Journal of Biological Chemistry 295 (26), 8692-8705, 2020
152020
Ionic strength and calcium regulate membrane interactions of myelin basic protein and the cytoplasmic domain of myelin protein zero
A Raasakka, NC Jones, SV Hoffmann, P Kursula
Biochemical and biophysical research communications 511 (1), 7-12, 2019
152019
Direct binding of the flexible C-terminal segment of periaxin to β4 integrin suggests a molecular basis for CMT4F
A Raasakka, H Linxweiler, PJ Brophy, DL Sherman, P Kursula
Frontiers in molecular neuroscience 12, 84, 2019
142019
Direct binding of the flexible C-terminal segment of periaxin to β4 integrin suggests a molecular basis for CMT4F: Supplementary Figure 1
A Raasakka, H Linxweiler, PJ Brophy, DL Sherman, P Kursula
14*2019
Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains
M Myllykoski, A Sutinen, MK Koski, JP Kallio, A Raasakka, J Myllyharju, ...
Journal of Biological Chemistry 296, 100197, 2021
132021
Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment
PAG Lillebostad, A Raasakka, SJ Hjellbrekke, S Patil, T Røstbø, H Hollås, ...
Biomolecules 10 (4), 660, 2020
122020
Neuropathy-related mutations alter the membrane binding properties of the human myelin protein P0 cytoplasmic tail
A Raasakka, S Ruskamo, R Barker, OC Krokengen, GH Vatne, ...
PloS one 14 (6), e0216833, 2019
112019
Structure of the complete dimeric human GDAP1 core domain provides insights into ligand binding and clustering of disease mutations
GTT Nguyen, A Sutinen, A Raasakka, G Muruganandam, R Loris, ...
bioRxiv, 2020
92020
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Articles 1–20