Dr Dimitrios Vlachakis
Dr Dimitrios Vlachakis
As. Professor @ Genetics Lab, Biotech, AUA @ URI Medical School Athens @ BRF Academy of Athens @ KCL
Verified email at - Homepage
Cited by
Cited by
Current state-of-the-art molecular dynamics methods and applications
D Vlachakis, E Bencurova, N Papangelopoulos, S Kossida
Advances in protein chemistry and structural biology 94, 269-313, 2014
Discovery of a novel HCV helicase inhibitor by a de novo drug design approach
S Kandil, S Biondaro, D Vlachakis, AC Cummins, A Coluccia, C Berry, ...
Bioorganic & medicinal chemistry letters 19 (11), 2935-2937, 2009
EnzyNet: enzyme classification using 3D convolutional neural networks on spatial representation
A Amidi, S Amidi, D Vlachakis, V Megalooikonomou, N Paragios, ...
PeerJ 6, e4750, 2018
Competitive inhibition of human poly (A)-specific ribonuclease (PARN) by synthetic fluoro-pyranosyl nucleosides
NAA Balatsos, D Vlachakis, P Maragozidis, S Manta, D Anastasakis, ...
Biochemistry 48 (26), 6044-6051, 2009
A novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the …
NC Nicolaides, ML Roberts, T Kino, G Braatvedt, DE Hurt, E Katsantoni, ...
The Journal of Clinical Endocrinology & Metabolism 99 (5), E902-E907, 2014
Genomic big data hitting the storage bottleneck
L Papageorgiou, P Eleni, S Raftopoulou, M Mantaiou, ...
EMBnet. journal 24, 2018
State-of-the-art technology in modern computer-aided drug design
GA Dalkas, D Vlachakis, D Tsagkrasoulis, A Kastania, S Kossida
Briefings in bioinformatics 14 (6), 745-752, 2013
Transcription factors and evolution: an integral part of gene expression
T Mitsis, A Efthimiadou, F Bacopoulou, D Vlachakis, GP Chrousos, ...
World Academy of Sciences Journal 2 (1), 3-8, 2020
Gromita: a fully integrated graphical user interface to gromacs 4
D Sellis, D Vlachakis, M Vlassi
Bioinformatics and biology insights 3, BBI. S3207, 2009
A holistic evolutionary and structural study of flaviviridae provides insights into the function and inhibition of HCV helicase
D Vlachakis, VL Koumandou, S Kossida
PeerJ 1, e74, 2013
Introducing Drugster: a comprehensive and fully integrated drug design, lead and structure optimization toolkit
D Vlachakis, D Tsagrasoulis, V Megalooikonomou, S Kossida
Bioinformatics 29 (1), 126-128, 2013
An updated evolutionary study of Flaviviridae NS3 helicase and NS5 RNA-dependent RNA polymerase reveals novel invariable motifs as potential pharmacological targets
L Papageorgiou, S Loukatou, K Sofia, D Maroulis, D Vlachakis
Molecular BioSystems 12 (7), 2080-2093, 2016
Phosphorylation of the arginine/serine repeats of lamin B receptor by SRPK1—Insights from molecular dynamics simulations
D Sellis, V Drosou, D Vlachakis, N Voukkalis, T Giannakouros, M Vlassi
Biochimica et Biophysica Acta (BBA)-General Subjects 1820 (1), 44-55, 2012
Modelling and mutational evidence identify the substrate binding site and functional elements in APC amino acid transporters
I Vangelatos, D Vlachakis, V Sophianopoulou, G Diallinas
Molecular membrane biology 26 (5-7), 356-370, 2009
Directed evolution of Tau class glutathione transferases reveals a site that regulates catalytic efficiency and masks co-operativity
I Axarli, AW Muleta, D Vlachakis, S Kossida, G Kotzia, A Maltezos, ...
Biochemical Journal 473 (5), 559-570, 2016
A novel mutation of the hGR gene causing Chrousos syndrome
NC Nicolaides, EB Geer, D Vlachakis, ML Roberts, AMG Psarra, ...
European Journal of Clinical Investigation 45 (8), 782-791, 2015
Antiviral stratagems against HIV-1 using RNA interference (RNAi) technology
D Vlachakis, G Tsiliki, A Pavlopoulou, MG Roubelakis, SC Tsaniras, ...
Evolutionary Bioinformatics 9, EBO. S11412, 2013
Automatic single-and multi-label enzymatic function prediction by machine learning
S Amidi, A Amidi, D Vlachakis, N Paragios, EI Zacharaki
PeerJ 5, e3095, 2017
Functional toll-like receptor 9 expression and CXCR3 ligand release in pulmonary sarcoidosis
J Schnerch, A Prasse, D Vlachakis, KL Schuchardt, DV Pechkovsky, ...
American journal of respiratory cell and molecular biology 55 (5), 749-757, 2016
Antibody drug conjugate bioinformatics: drug delivery through the letterbox
D Vlachakis, S Kossida
Computational and mathematical methods in medicine 2013, 2013
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