| Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain D Moechars, I Dewachter, K Lorent, D Reversé, V Baekelandt, A Naidu, ... Journal of Biological Chemistry 274 (10), 6483-6492, 1999 | 822 | 1999 |
| α-Synuclein strains cause distinct synucleinopathies after local and systemic administration W Peelaerts, L Bousset, A Van der Perren, A Moskalyuk, R Pulizzi, ... Nature 522 (7556), 340-344, 2015 | 754 | 2015 |
| Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 … A Herreman, D Hartmann, W Annaert, P Saftig, K Craessaerts, L Serneels, ... Proceedings of the National Academy of Sciences 96 (21), 11872-11877, 1999 | 552 | 1999 |
| Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis L Parisiadou, C Xie, HJ Cho, X Lin, XL Gu, CX Long, E Lobbestael, ... Journal of Neuroscience 29 (44), 13971-13980, 2009 | 319 | 2009 |
| The Parkinson disease-associated leucine-rich repeat kinase 2 (LRRK2) is a dimer that undergoes intramolecular autophosphorylation E Greggio, I Zambrano, A Kaganovich, A Beilina, JM Taymans, V Daniëls, ... Journal of Biological Chemistry 283 (24), 16906-16914, 2008 | 317 | 2008 |
| Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease A Beilina, IN Rudenko, A Kaganovich, L Civiero, H Chau, SK Kalia, ... Proceedings of the National Academy of Sciences 111 (7), 2626-2631, 2014 | 293 | 2014 |
| Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain JM Taymans, LH Vandenberghe, CVD Haute, I Thiry, CM Deroose, ... Human gene therapy 18 (3), 195-206, 2007 | 283 | 2007 |
| Knockdown of transactive response DNA‐binding protein (TDP‐43) downregulates histone deacetylase 6 FC Fiesel, A Voigt, SS Weber, C Van den Haute, A Waldenmaier, ... The EMBO journal 29 (1), 209-221, 2010 | 239 | 2010 |
| Distribution of PINK1 and LRRK2 in rat and mouse brain JM Taymans, C Van den Haute, V Baekelandt Journal of neurochemistry 98 (3), 951-961, 2006 | 188 | 2006 |
| Neuronal hyperactivity accelerates depletion of neural stem cells and impairs hippocampal neurogenesis A Sierra, S Martín-Suárez, R Valcárcel-Martín, J Pascual-Brazo, ... Cell stem cell 16 (5), 488-503, 2015 | 187 | 2015 |
| MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein HJ Cho, G Liu, SM Jin, L Parisiadou, C Xie, J Yu, L Sun, B Ma, J Ding, ... Human molecular genetics 22 (3), 608-620, 2013 | 184 | 2013 |
| Upscaling of lentiviral vector production by tangential flow filtration M Geraerts, M Michiels, V Baekelandt, Z Debyser, R Gijsbers The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 181 | 2005 |
| Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis Q Remijsen, V Goossens, S Grootjans, C Van Den Haute, ... Cell death & disease 5 (1), e1004-e1004, 2014 | 179 | 2014 |
| Optimized lentiviral vector production and purification procedure prevents immune response after transduction of mouse brain V Baekelandt, K Eggermont, M Michiels, B Nuttin, Z Debyser Gene therapy 10 (23), 1933-1940, 2003 | 176 | 2003 |
| Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance B Heeman, C Van den Haute, SA Aelvoet, F Valsecchi, RJ Rodenburg, ... Journal of cell science 124 (7), 1115-1125, 2011 | 169 | 2011 |
| Comparison of lentiviral vector titration methods M Geraerts, S Willems, V Baekelandt, Z Debyser, R Gijsbers BMC biotechnology 6 (1), 1-10, 2006 | 169 | 2006 |
| The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites E Greggio, JM Taymans, EY Zhen, J Ryder, R Vancraenenbroeck, ... Biochemical and biophysical research communications 389 (3), 449-454, 2009 | 163 | 2009 |
| Regulation of astrocyte inflammatory responses by the Parkinson's disease‐associated gene DJ–1 J Waak, SS Weber, A Waldenmaier, K Görner, M Alunni‐Fabbroni, ... The FASEB Journal 23 (8), 2478-2489, 2009 | 163 | 2009 |
| Automated quantitative gait analysis in animal models of movement disorders C Vandeputte, JM Taymans, C Casteels, F Coun, Y Ni, K Van Laere, ... BMC neuroscience 11 (1), 1-11, 2010 | 162 | 2010 |
| Highly efficient multicistronic lentiviral vectors with peptide 2A sequences A Ibrahimi, GV Velde, V Reumers, J Toelen, I Thiry, C Vandeputte, S Vets, ... Human gene therapy 20 (8), 845-860, 2009 | 160 | 2009 |
