| Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 2703 | 2012 |
| Epigenomic alterations define lethal CIMP-positive ependymomas of infancy SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ... Nature 506 (7489), 445-450, 2014 | 653 | 2014 |
| Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ... Nature genetics 46 (5), 451-456, 2014 | 644 | 2014 |
| Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma N Zhukova, V Ramaswamy, M Remke, E Pfaff, DJH Shih, DC Martin, ... Journal of Clinical Oncology 31 (23), 2927-2935, 2013 | 525 | 2013 |
| BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ... Journal of clinical oncology 33 (9), 1015-1022, 2015 | 298 | 2015 |
| Methylation of the TERT promoter and risk stratification of childhood brain tumours: an integrative genomic and molecular study P Castelo-Branco, S Choufani, S Mack, D Gallagher, C Zhang, T Lipman, ... The lancet oncology 14 (6), 534-542, 2013 | 296 | 2013 |
| Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer R Leão, JD Apolónio, D Lee, A Figueiredo, U Tabori, P Castelo-Branco Journal of biomedical science 25, 1-12, 2018 | 266 | 2018 |
| Polypyrimidine tract binding protein modulates efficiency of polyadenylation P Castelo-Branco, A Furger, M Wollerton, C Smith, A Moreira, N Proudfoot Molecular and cellular biology 24 (10), 4174-4183, 2004 | 233 | 2004 |
| DNA hypermethylation within TERT promoter upregulates TERT expression in cancer DD Lee, R Leao, M Komosa, M Gallo, CH Zhang, T Lipman, M Remke, ... The Journal of clinical investigation 129 (1), 223-229, 2019 | 198 | 2019 |
| Serum miRNA predicts viable disease after chemotherapy in patients with testicular nonseminoma germ cell tumor R Leão, T van Agthoven, A Figueiredo, MAS Jewett, K Fadaak, J Sweet, ... The Journal of urology 200 (1), 126-135, 2018 | 141 | 2018 |
| Roadmap of DNA methylation in breast cancer identifies novel prognostic biomarkers BP de Almeida, JD Apolónio, A Binnie, P Castelo-Branco BMC cancer 19, 1-12, 2019 | 133 | 2019 |
| Cellular interactions in the tumor microenvironment: the role of secretome BR da Cunha, C Domingos, ACB Stefanini, T Henrique, GM Polachini, ... Journal of Cancer 10 (19), 4574, 2019 | 116 | 2019 |
| Cancer stem cells in prostate cancer: implications for targeted therapy R Leão, C Domingos, A Figueiredo, R Hamilton, U Tabori, ... Urologia internationalis 99 (2), 125-136, 2017 | 94 | 2017 |
| Trichostatin A and oncolytic HSV combination therapy shows enhanced antitumoral and antiangiogenic effects TC Liu, P Castelo-Branco, SD Rabkin, RL Martuza Molecular Therapy 16 (6), 1041-1047, 2008 | 91 | 2008 |
| Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer R Leão, D Lee, A Figueiredo, T Hermanns, P Wild, M Komosa, I Lau, ... International journal of cancer 144 (7), 1676-1684, 2019 | 81 | 2019 |
| A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study P Castelo-Branco, R Leão, T Lipman, B Campbell, D Lee, A Price, ... Oncotarget 7 (36), 57726, 2016 | 79 | 2016 |
| Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition P Castelo-Branco, C Zhang, T Lipman, M Fujitani, L Hansford, I Clarke, ... Clinical Cancer Research 17 (1), 111-121, 2011 | 69 | 2011 |
| Monoallelic expression determines oncogenic progression and outcome in benign and malignant brain tumors EJ Walker, C Zhang, P Castelo-Branco, C Hawkins, W Wilson, N Zhukova, ... Cancer research 72 (3), 636-644, 2012 | 68 | 2012 |
| Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors J Mangerel, A Price, P Castelo-Branco, J Brzezinski, P Buczkowicz, ... Acta neuropathologica 128, 853-862, 2014 | 57 | 2014 |
| Epigenetics of sepsis A Binnie, JLY Tsang, P Hu, G Carrasqueiro, P Castelo-Branco, ... Critical Care Medicine 48 (5), 745-756, 2020 | 55 | 2020 |
