Sanaz Yahyanejad
Sanaz Yahyanejad
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NOTCH blockade combined with radiation therapy and temozolomide prolongs survival of orthotopic glioblastoma
S Yahyanejad, H King, VS Iglesias, PV Granton, LMO Barbeau, ...
Oncotarget 7 (27), 41251, 2016
Regulated proteolysis of NOTCH2 and NOTCH3 receptors by ADAM10 and presenilins
AJ Groot, R Habets, S Yahyanejad, CM Hodin, K Reiss, P Saftig, J Theys, ...
Molecular and cellular biology 34 (15), 2822-2832, 2014
High NOTCH activity induces radiation resistance in non small cell lung cancer
J Theys, S Yahyanejad, R Habets, P Span, L Dubois, K Paesmans, ...
Radiotherapy and oncology 108 (3), 440-445, 2013
Targeting Notch to overcome radiation resistance
S Yahyanejad, J Theys, M Vooijs
Oncotarget 7 (7), 7610, 2016
Human NOTCH2 is resistant to ligand-independent activation by metalloprotease Adam17
RAJ Habets, AJ Groot, S Yahyanejad, K Tiyanont, SC Blacklow, M Vooijs
Journal of Biological Chemistry 290 (23), 14705-14716, 2015
Complementary use of bioluminescence imaging and contrast-enhanced micro—computed tomography in an orthotopic brain tumor model
S Yahyanejad, PV Granton, NG Lieuwes, L Gilmour, L Dubois, J Theys, ...
Molecular imaging 13 (4), 7290.2014. 00038, 2014
An image guided small animal radiation therapy platform (SmART) to monitor glioblastoma progression and therapy response
S Yahyanejad, SJ van Hoof, J Theys, LMO Barbeau, PV Granton, ...
Radiotherapy and Oncology 116 (3), 467-472, 2015
The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition
J Hounjet, R Habets, MB Schaaf, TC Hendrickx, LMO Barbeau, ...
Oncogene 38 (27), 5457-5468, 2019
Pharmacologic profile of INT-1B3: A novel synthetic microRNA 193a-3p mimic for therapeutic intervention in oncology
S Yahyanejad, T de Gunst, I Schultz, H den Boer, M Raimo, B Telford, ...
Cancer Research 78 (13 Supplement), 4405-4405, 2018
OC-0617: the PARP inhibitor olaparib is effective as radiosensitizer at 10-fold lower doses than as single agent
R De Haan, CVM Verhagen, F Hageman, T Oostendorp, A Di Carli, ...
Radiotherapy and Oncology 115, S298-S299, 2015
Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic
MTJ van den Bosch, S Yahyanejad, MF Alemdehy, BJ Telford, T de Gunst, ...
Molecular Therapy-Nucleic Acids 23, 1161-1171, 2021
Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology
BJ Telford, S Yahyanejad, T de Gunst, HC den Boer, RM Vos, M Stegink, ...
Oncotarget 12 (5), 422, 2021
Anticancer microRNA and lipid formulations thereof
MM De Gunst, LAH Van Pinxteren, M Janicot, IJ Schultz, RQJ Schaapveld, ...
US Patent App. 16/966,869, 2021
S m ART-ER imaging and treatment of glioblastoma
PV Granton, S Yahyanejad, MA Vooijs
Journal of neuro-oncology 123 (2), 319-320, 2015
EP-1350: Malignant mucosal melanoma in the upper aerodigestive tract treated with carbon ion RT at CNAO: preliminary results
V Vitolo, P Fossati, M Bonora, A Iannalfi, MR Fiore, V Vischioni, E Ciurlia, ...
Radiotherapy and Oncology 115, S728, 2015
Phase I/Ib study with INT-1B3, a novel LNP-formulated micro-RNA (miR-193a-3p mimic) therapeutic for patients with advanced solid cancer.
N Kotecki, F Opdam, D Robbrecht, M Strijbos, K Kroon, M Janicot, ...
Journal of Clinical Oncology 39 (15_suppl), TPS2666-TPS2666, 2021
PO-023 Chloroquine sensitises oncogenic NOTCH1 driven human T cell leukaemia to γ-secretase inhibition
J Hounjet, R Habets, MB Schaaf, TC Hendrickx, LMO Barbeau, ...
ESMO Open 3 (Suppl 2), A29-A30, 2018
State of the art and future developments of small animal imaging and radiotherapy platforms
F Verhaegen, S Van Hoof, L Schyns, S Yahyanejad, B Van der Heyden, ...
Radiotherapy and Oncology 127, S119-S119, 2018
Benefits, limitations and opportunities of NOTCH inhibitors for treatment of glioma
S Yahyanejad, PV Granton, A Hoeben, MA Vooijs
Translational Cancer Research 5, S290-S295, 2016
OC-0237: Adding Notch inhibition increases efficacy of standard of care treatment in glioblastoma
S Yahyanejad, H King, V Iglesias, P Granton, L Barbeau, S Van Hoof, ...
Radiotherapy and Oncology 119, S107-S108, 2016
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