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Maria Candida Cesta
Maria Candida Cesta
Scientific Collaborations & Funding Director, Dompé farmaceutici s.p.a
Email confirmado em dompe.com - Página inicial
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Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury
R Bertini, M Allegretti, C Bizzarri, A Moriconi, M Locati, G Zampella, ...
Proceedings of the National Academy of Sciences 101 (32), 11791-11796, 2004
3432004
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors
M Allegretti, R Bertini, MC Cesta, C Bizzarri, R Di Bitondo, V Di Cioccio, ...
Journal of medicinal chemistry 48 (13), 4312-4331, 2005
1332005
Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2
A Moriconi, MC Cesta, MN Cervellera, A Aramini, S Coniglio, S Colagioia, ...
Journal of medicinal chemistry 50 (17), 3984-4002, 2007
1042007
Current status of chemokine receptor inhibitors in development
M Allegretti, MC Cesta, A Garin, AEI Proudfoot
Immunology letters 145 (1-2), 68-78, 2012
752012
Receptor binding mode and pharmacological characterization of a potent and selective dual CXCR1/CXCR2 non‐competitive allosteric inhibitor
R Bertini, LS Barcelos, AR Beccari, B Cavalieri, A Moriconi, C Bizzarri, ...
British journal of pharmacology 165 (2), 436-454, 2012
632012
A modified palladium catalysed reductive amination procedure
V Berdini, MC Cesta, R Curti, G D'Anniballe, N Di Bello, G Nano, ...
Tetrahedron 58 (28), 5669-5674, 2002
562002
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach
L Aureli, G Cruciani, MC Cesta, R Anacardio, L De Simone, A Moriconi
Journal of medicinal chemistry 48 (7), 2469-2479, 2005
522005
A Practical Synthesis of 7-Azaindolylcarboxy-e ndo-tropanamide (DF 1012)
M Allegretti, R Anacardio, MC Cesta, R Curti, M Mantovanini, G Nano, ...
Organic process research & development 7 (2), 209-213, 2003
442003
One-pot, new stereoselective synthesis of endo-tropanamine
M Allegretti, V Berdini, MC Cesta, R Curti, L Nicolini, A Topai
Tetrahedron Letters 42 (25), 4257-4259, 2001
442001
Supercritical fluids processing: preparation of protein microparticles and their stablilisation
M Gentile, C Di Palma, MC Cesta
US Patent 7,250,152, 2007
342007
Targeting FR-expressing cells in ovarian cancer with Fab-functionalized nanoparticles: a full study to provide the proof of principle from in vitro to in vivo
A Quarta, D Bernareggi, F Benigni, E Luison, G Nano, S Nitti, MC Cesta, ...
Nanoscale 7 (6), 2336-2351, 2015
332015
Allosteric modulation of chemoattractant receptors
M Allegretti, MC Cesta, M Locati
Frontiers in Immunology 7, 170, 2016
262016
Sulfonic acids, their derivatives and pharmaceutical compositions containing them
M Allegretti, A Aramini, MC Cesta, R Bertini, C Bizzarri, F Colotta
US Patent 7,737,139, 2010
222010
The role of interleukin-8 in lung inflammation and injury: Implications for the management of COVID-19 and hyperinflammatory acute respiratory distress syndrome
MC Cesta, M Zippoli, C Marsiglia, EM Gavioli, F Mantelli, M Allegretti, ...
Frontiers in pharmacology 12, 3931, 2022
212022
Repurposing the estrogen receptor modulator raloxifene to treat SARS-CoV-2 infection
M Allegretti, MC Cesta, M Zippoli, A Beccari, C Talarico, F Mantelli, ...
Cell Death & Differentiation 29 (1), 156-166, 2022
212022
Quaternary ammonium salts of omega-aminoalkylamides of r-2-aryl-propionic acids and pharmaceutical compositions containing them
M Allegretti, R Bertini, C Bizzarri, MC Cesta
US Patent 7,026,510, 2006
212006
Synthesis and structure-activity relationships of new acetylcholinesterase inhibitors: Morpholinoalkylcarbamoyloxyeseroline derivatives
MA Alisi, M Brufani, L Filocamo, G Gostoli, E Licandro, MC Cesta, ...
Bioorganic & Medicinal Chemistry Letters 5 (18), 2077-2080, 1995
181995
(R)-arylalkylamino derivatives and pharmaceutical compositions containing them
M Allegretti, A Moriconi, A Aramini, MC Cesta, A Beccari, R Bertini
US Patent 8,026,367, 2011
142011
Synthesis of inositol phospholipids with thiophosphoester bonds
MA Alisi, M Brufani, L Filocamo, G Gostoli, S Maiorana, MC Cesta, ...
Tetrahedron letters 33 (50), 7793-7796, 1992
131992
Emerging role of C5 complement pathway in peripheral neuropathies: current treatments and future perspectives
C Giorgio, M Zippoli, P Cocchiaro, V Castelli, G Varrassi, A Aramini, ...
Biomedicines 9 (4), 399, 2021
102021
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