| Chiral 6, 7-bis (hydroxymethyl)-1H, 3H-pyrrolo [1, 2-c] thiazoles with anti-breast cancer properties MIL Soares, AF Brito, M Laranjo, JA Paixão, MF Botelho, TMVDP e Melo European journal of medicinal chemistry 60, 254-262, 2013 | 68 | 2013 |
| Synthesis of Chiral Pyrrolo[1,2-c]thiazoles via Intramolecular Dipolar Cycloaddition of Münchnones: An Interesting Rearrangement to Pyrrolo[1,2-c]thiazines TMVD Pinho e Melo, MIL Soares, AMAR Gonsalves, JA Paixão, AM Beja, ... The Journal of Organic Chemistry 67 (12), 4045-4054, 2002 | 37 | 2002 |
| Targeting triple-negative breast cancer cells with 6, 7-bis (hydroxymethyl)-1H, 3H-pyrrolo [1, 2-c] thiazoles K Santos, M Laranjo, AM Abrantes, AF Brito, C Gonçalves, ABS Ribeiro, ... European Journal of Medicinal Chemistry 79, 273-281, 2014 | 35 | 2014 |
| N-Vinyl- and C-Vinylpyrroles from Azafulvenium Methides. Flash Vacuum Pyrolysis Route to 5-Oxo-5H-pyrrolizines and 1-Azabenzo[f]azulenes TMVD Pinho e Melo, MIL Soares, AMAR Gonsalves, JA Paixao, AM Beja, ... The Journal of Organic Chemistry 70 (17), 6629-6638, 2005 | 34 | 2005 |
| A selective p53 activator and anticancer agent to improve colorectal cancer therapy H Ramos, MIL Soares, J Silva, L Raimundo, J Calheiros, C Gomes, F Reis, ... Cell Reports 35 (2), 2021 | 30 | 2021 |
| Recent advances in the synthesis of spiro‐β‐lactams and spiro‐δ‐lactams NG Alves, AJS Alves, MIL Soares, TMVD Pinho e Melo Advanced Synthesis & Catalysis 363 (10), 2464-2501, 2021 | 29 | 2021 |
| Chemistry of diazafulvenium methides in the synthesis of functionalized pyrazoles TMVD Pinho e Melo, CM Nunes, MIL Soares, JA Paixao, A Matos Beja, ... The Journal of Organic Chemistry 72 (12), 4406-4415, 2007 | 28 | 2007 |
| Thiazolo[3,4-b]indazole-2,2-dioxides as Masked Extended Dipoles: Pericyclic Reactions of Benzodiazafulvenium Methides MIL Soares, CM Nunes, CSB Gomes, TMVD Pinho e Melo The Journal of organic chemistry 78 (2), 628-637, 2012 | 27 | 2012 |
| Microwave-assisted generation and reactivity of aza-and diazafulvenium methides: heterocycles via pericyclic reactions MIL Soares, TMVDP e Melo Tetrahedron Letters 49 (33), 4889-4893, 2008 | 27 | 2008 |
| One-pot telescoped synthesis of thiazole derivatives from β-keto esters and thioureas promoted by tribromoisocyanuric acid VSC de Andrade, MCS de Mattos Synthesis 50 (24), 4867-4874, 2018 | 26 | 2018 |
| Strategies and methodologies for the construction of spiro-γ-lactams: an update AJS Alves, NG Alves, MIL Soares, TMVDP e Melo Organic Chemistry Frontiers 8 (13), 3543-3593, 2021 | 24 | 2021 |
| Thermolysis of 1-(thiophen-2-yl)-1H-tetrazoles: a route to thiophene-fused imidazoles and pyrimidines MIL Soares, ACF de Lyra, MSC Henriques, JA Paixão, TMVDP e Melo Tetrahedron 71 (21), 3343-3350, 2015 | 23 | 2015 |
| Synthesis and structure-activity relationships of new chiral spiro-β-lactams highly active against HIV-1 and Plasmodium NG Alves, I Bártolo, AJS Alves, D Fontinha, D Francisco, SMM Lopes, ... European Journal of Medicinal Chemistry 219, 113439, 2021 | 21 | 2021 |
| Spiro-lactams as novel antimicrobial agents AJS Alves, NG Alves, CC Caratão, MIM Esteves, D Fontinha, I Bártolo, ... Current Topics in Medicinal Chemistry 20 (2), 140-152, 2020 | 21 | 2020 |
| 1, 3-dipolar cycloadditions involving allenes: synthesis of five-membered rings AL Cardoso, MIL Soares Current Organic Chemistry 23 (27), 3064-3134, 2019 | 21 | 2019 |
| Chiral 6-hydroxymethyl-1H, 3H-pyrrolo [1, 2-c] thiazoles: novel antitumor DNA monoalkylating agents MIL Soares, AF Brito, M Laranjo, AM Abrantes, MF Botelho, JA Paixão, ... European journal of medicinal chemistry 45 (10), 4676-4681, 2010 | 18 | 2010 |
| Flash vacuum pyrolysis of 2, 2-dioxo-1H, 3H-pyrrolo [1, 2-c] thiazoles and 2-vinyl-1H-pyrroles MIL Soares, SMM Lopes, PF Cruz, RMM Brito, TMVDP e Melo Tetrahedron 64 (41), 9745-9753, 2008 | 18 | 2008 |
| Phosphane‐catalyzed [3+ 2] Annulation of Allenoates with 3‐Nitro‐2H‐chromenes: Synthesis of Tetrahydrocyclopenta [c] chromenes MI Soares, CSB Gomes, SCC Nunes, AACC Pais, TMVD Pinho e Melo European Journal of Organic Chemistry 2019 (31-32), 5441-5451, 2019 | 16 | 2019 |
| Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages N Domingues, LMBB Estronca, J Silva, MR Encarnação, R Mateus, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2017 | 16 | 2017 |
| ‘Higher-order’azomethine ylides in the synthesis of functionalized pyrroles and 5-oxo-5H-pyrrolizines TMVDP e Melo, MIL Soares, CM Nunes Tetrahedron 63 (8), 1833-1841, 2007 | 13 | 2007 |
José António PaixãoCFisUC, Physics Dept. University of CoimbraVerified email at pollux.fis.uc.pt
