Maria José Umbelino Ferreira
Maria José Umbelino Ferreira
Faculty of Pharmacy, Universidade de Lisboa, Research Institute for Medicines (iMed.ULisboa)
Email confirmado em ff.ulisboa.pt
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Inhibition of multidrug resistance of cancer cells by natural diterpenes, triterpenes and carotenoids
J Molnár, N Gyémánt, M Tanaka, J Hohmann, E Bergmann-Leitner, ...
Current pharmaceutical design 12 (3), 287-311, 2006
1192006
Molecular docking characterizes substrate-binding sites and efflux modulation mechanisms within P-glycoprotein.
RJ Ferreira, MJU Ferreira, DJVA dos Santos
Journal of chemical information and modeling 53 (7), 1747-1760, 2013
1052013
Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids
N Duarte, A Varga, G Cherepnev, R Radics, J Molnár, MJU Ferreira
Bioorganic & medicinal chemistry 15 (1), 546-554, 2007
982007
Evaluation of the Antiviral and Antimicrobial Activities of Triterpenes Isolated from Euphorbia segetalis
AM Madureira, JR Ascenso, L Valdeira, A Duarte, JP Frade, G Freitas, ...
Natural product research 17 (5), 375-380, 2003
902003
Insights on P-glycoprotein’s efflux mechanism obtained by molecular dynamics simulations
RJ Ferreira, MJU Ferreira, DJVA dos Santos
Journal of Chemical Theory and Computation 8 (6), 1853-1864, 2012
772012
Antimycobacterial evaluation and preliminary phytochemical investigation of selected medicinal plants traditionally used in Mozambique
X Luo, D Pires, JA Aínsa, B Gracia, S Mulhovo, A Duarte, E Anes, ...
Journal of Ethnopharmacology 137 (1), 114-120, 2011
732011
Bioactive Diterpenoids, a New Jatrophane and Two e nt-Abietanes, and Other Constituents from Euphorbia p ubescens
C Valente, M Pedro, A Duarte, MSJ Nascimento, PM Abreu, MJU Ferreira
Journal of natural products 67 (5), 902-904, 2004
732004
Antitumor activity of terpenoids against classical and atypical multidrug resistant cancer cells
H Lage, N Duarte, C Coburger, A Hilgeroth, MJU Ferreira
Phytomedicine 17 (6), 441-448, 2010
712010
New macrocyclic lathyrane diterpenes, from Euphorbia lagascae, as inhibitors of multidrug resistance of tumour cells
N Duarte, N Gyémánt, PM Abreu, J Molnár, MJU Ferreira
Planta medica 72 (02), 162-168, 2006
682006
Interaction between doxorubicin and the resistance modifier stilbene on multidrug resistant mouse lymphoma and human breast cancer cells
MJU Ferreira, N Duarte, N Gyemant, R Radics, G Cherepnev, A Varga, ...
Anticancer research 26 (5A), 3541-3546, 2006
592006
Multidrug Resistance Reversal and Apoptosis Induction in Human Colon Cancer Cells by Some Flavonoids Present in Citrus Plants
O Wesołowska, J Wiśniewski, K Środa-Pomianek, A Bielawska-Pohl, ...
Journal of natural products 75 (11), 1896-1902, 2012
582012
Toward a Better Pharmacophore Description of P-Glycoprotein Modulators, Based on Macrocyclic Diterpenes from Euphorbia Species
RJ Ferreira, DJVA dos Santos, MJU Ferreira, RC Guedes
Journal of chemical information and modeling 51 (6), 1315-1324, 2011
572011
Induction of apoptosis in HuH-7 cancer cells by monoterpene and β-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegans
TA Mansoor, RM Ramalho, S Mulhovo, CMP Rodrigues, MJU Ferreira
Bioorganic & medicinal chemistry letters 19 (15), 4255-4258, 2009
572009
Isoflavones as apoptosis inducers in human hepatoma HuH‐7 cells
TA Mansoor, RM Ramalho, X Luo, C Ramalhete, CMP Rodrigues, ...
Phytotherapy research 25 (12), 1819-1824, 2011
562011
Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro and ex vivo within human macrophages
X Luo, D Pires, JA Aínsa, B Gracia, N Duarte, S Mulhovo, E Anes, ...
Journal of ethnopharmacology 146 (1), 417-422, 2013
522013
Antibacterial activity of some African medicinal plants used traditionally against infectious diseases
AM Madureira, C Ramalhete, S Mulhovo, A Duarte, MJU Ferreira
Pharmaceutical Biology 50 (4), 481-489, 2012
522012
A new sesquiterpene-coumarin ether and a new abietane diterpene and their effects as inhibitors of P-glycoprotein
AM Madureira, A Molnár, PM Abreu, J Molnár, MJU Ferreira
Planta medica 70 (09), 828-833, 2004
522004
Pubescenes, jatrophane diterpenes, from Euphorbia pubescens, with multidrug resistance reversing activity on mouse lymphoma cells
C Valente, MJU Ferreira, PM Abreu, N Gyémánt, K Ugocsai, J Hohmann, ...
Planta medica 70 (01), 81-84, 2004
522004
P-glycoprotein and membrane roles in multidrug resistance
RJ Ferreira, DJVA dos Santos, MJU Ferreira
Future medicinal chemistry 7 (7), 929-946, 2015
512015
Enhancing macrocyclic diterpenes as multidrug-resistance reversers: structure–activity studies on jolkinol D derivatives
M Reis, RJ Ferreira, MMM Santos, DJVA Dos Santos, J Molnár, ...
Journal of medicinal chemistry 56 (3), 748-760, 2013
502013
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