Chromone: a valid scaffold in medicinal chemistry A Gaspar, MJ Matos, J Garrido, E Uriarte, F Borges Chemical reviews 114 (9), 4960-4992, 2014 | 733 | 2014 |
Hydroxycinnamic acid antioxidants: an electrochemical overview J Teixeira, A Gaspar, EM Garrido, J Garrido, F Borges BioMed research international 2013 (1), 251754, 2013 | 474 | 2013 |
Chromone as a privileged scaffold in drug discovery: recent advances: miniperspective J Reis, A Gaspar, N Milhazes, F Borges Journal of medicinal chemistry 60 (19), 7941-7957, 2017 | 329 | 2017 |
Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors A Gaspar, T Silva, M Yánez, D Vina, F Orallo, F Ortuso, E Uriarte, S Alcaro, ... Journal of medicinal chemistry 54 (14), 5165-5173, 2011 | 166 | 2011 |
Alkyl esters of hydroxycinnamic acids with improved antioxidant activity and lipophilicity protect PC12 cells against oxidative stress J Garrido, A Gaspar, EM Garrido, R Miri, M Tavakkoli, S Pourali, L Saso, ... Biochimie 94 (4), 961-967, 2012 | 130 | 2012 |
Synthesis and antioxidant activity of long chain alkyl hydroxycinnamates JC Menezes, SP Kamat, JAS Cavaleiro, A Gaspar, J Garrido, F Borges European journal of medicinal chemistry 46 (2), 773-777, 2011 | 123 | 2011 |
Dietary phenolic acids and derivatives. Evaluation of the antioxidant activity of sinapic acid and its alkyl esters A Gaspar, M Martins, P Silva, EM Garrido, J Garrido, O Firuzi, R Miri, ... Journal of agricultural and food chemistry 58 (21), 11273-11280, 2010 | 120 | 2010 |
New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives A Gaspar, EM Garrido, M Esteves, E Quezada, N Milhazes, J Garrido, ... European Journal of Medicinal Chemistry 44 (5), 2092-2099, 2009 | 110 | 2009 |
Discovery of new chemical entities for old targets: insights on the lead optimization of chromone-based monoamine oxidase B (MAO-B) inhibitors J Reis, F Cagide, D Chavarria, T Silva, C Fernandes, A Gaspar, E Uriarte, ... Journal of medicinal chemistry 59 (12), 5879-5893, 2016 | 99 | 2016 |
Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors A Gaspar, J Reis, A Fonseca, N Milhazes, D Viña, E Uriarte, F Borges Bioorganic & medicinal chemistry letters 21 (2), 707-709, 2011 | 96 | 2011 |
Biodegradable antioxidant chitosan films useful as an anti-aging skin mask CR Afonso, RS Hirano, AL Gaspar, EGL Chagas, RA Carvalho, FV Silva, ... International journal of biological macromolecules 132, 1262-1273, 2019 | 89 | 2019 |
Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors AM Helguera, A Pérez-Garrido, A Gaspar, J Reis, F Cagide, D Vina, ... European journal of medicinal chemistry 59, 75-90, 2013 | 76 | 2013 |
Exploring nature profits: Development of novel and potent lipophilic antioxidants based on galloyl–cinnamic hybrids J Teixeira, T Silva, S Benfeito, A Gaspar, EM Garrido, J Garrido, F Borges European journal of medicinal chemistry 62, 289-296, 2013 | 66 | 2013 |
Chromone-2-and-3-carboxylic acids inhibit differently monoamine oxidases A and B S Alcaro, A Gaspar, F Ortuso, N Milhazes, F Orallo, E Uriarte, M Yáñez, ... Bioorganic & medicinal chemistry letters 20 (9), 2709-2712, 2010 | 66 | 2010 |
Antioxidant phenolic esters with potential anticancer activity: A Raman spectroscopy study R Calheiros, NFL Machado, SM Fiuza, A Gaspar, J Garrido, N Milhazes, ... Journal of Raman Spectroscopy: An International Journal for Original Work in …, 2008 | 61 | 2008 |
The chemistry toolbox of multitarget-directed ligands for Alzheimer's disease F Mesiti, D Chavarria, A Gaspar, S Alcaro, F Borges European journal of medicinal chemistry 181, 111572, 2019 | 58 | 2019 |
Antioxidant versus cytotoxic properties of hydroxycinnamic acid derivatives–a new paradigm in phenolic research M Esteves, C Siquet, A Gaspar, V Rio, JB Sousa, S Reis, MPM Marques, ... Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2008 | 58 | 2008 |
Discovery of two new classes of potent monoamine oxidase-B inhibitors by tricky chemistry F Cagide, T Silva, J Reis, A Gaspar, F Borges, LR Gomes, JN Low Chemical communications 51 (14), 2832-2835, 2015 | 54 | 2015 |
Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acid scaffold JÉ Teixeira, P Soares, S Benfeito, A Gaspar, J Garrido, MP Murphy, ... Free radical research 46 (5), 600-611, 2012 | 54 | 2012 |
Discovery of novel A3 adenosine receptor ligands based on chromone scaffold A Gaspar, J Reis, S Kachler, S Paoletta, E Uriarte, KN Klotz, S Moro, ... Biochemical Pharmacology 84 (1), 21-29, 2012 | 53 | 2012 |