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Ana Fernandes-Platzgummer
Ana Fernandes-Platzgummer
Email confirmado em ist.utl.pt
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Mouse embryonic stem cell expansion in a microcarrier-based stirred culture system
AM Fernandes, TG Fernandes, MM Diogo, CL da Silva, D Henrique, ...
Journal of biotechnology 132 (2), 227-236, 2007
2182007
A xenogeneic‐free bioreactor system for the clinical‐scale expansion of human mesenchymal stem/stromal cells
F Dos Santos, A Campbell, A Fernandes‐Platzgummer, PZ Andrade, ...
Biotechnology and bioengineering 111 (6), 1116-1127, 2014
1742014
Delta one T cells for immunotherapy of chronic lymphocytic leukemia: clinical-grade expansion/differentiation and preclinical proof of concept
AR Almeida, DV Correia, A Fernandes-Platzgummer, CL da Silva, ...
Clinical Cancer Research 22 (23), 5795-5804, 2016
1692016
Scalable production of human mesenchymal stromal cell-derived extracellular vesicles under serum-/xeno-free conditions in a microcarrier-based bioreactor culture system
M de Almeida Fuzeta, N Bernardes, FD Oliveira, AC Costa, ...
Frontiers in Cell and Developmental Biology 8, 553444, 2020
912020
Scalable microcarrier-based manufacturing of mesenchymal stem/stromal cells
AM de Soure, A Fernandes-Platzgummer, CL da Silva, JMS Cabral
Journal of biotechnology 236, 88-109, 2016
892016
A xeno‐free microcarrier‐based stirred culture system for the scalable expansion of human mesenchymal stem/stromal cells isolated from bone marrow and adipose tissue
JG Carmelo, A Fernandes‐Platzgummer, MM Diogo, CL da Silva, ...
Biotechnology journal 10 (8), 1235-1247, 2015
802015
Stirred tank bioreactor culture combined with serum‐/xenogeneic‐free culture medium enables an efficient expansion of umbilical cord‐derived mesenchymal stem/stromal cells
A Mizukami, A Fernandes‐Platzgummer, JG Carmelo, K Swiech, ...
Biotechnology journal 11 (8), 1048-1059, 2016
752016
Integrated purification of monoclonal antibodies directly from cell culture medium with aqueous two-phase systems
M Silva, A Fernandes-Platzgummer, R Aires-Barros, A Azevedo
Separation and Purification Technology 132, 330-335, 2014
612014
Integrated culture platform based on a human platelet lysate supplement for the isolation and scalable manufacturing of umbilical cord matrix-derived mesenchymal stem/stromal cells
AM de Soure, A Fernandes-Platzgummer, F Moreira, C Lilaia, SH Liu, ...
Journal of Tissue Engineering and Regenerative Medicine, doi: 10.1002/term.2200, 2016
602016
Scale‐up of mouse embryonic stem cell expansion in stirred bioreactors
A Fernandes‐Platzgummer, MM Diogo, RP Baptista, CL Silva, ...
Biotechnology progress 27 (5), 1421-1432, 2011
512011
Mesenchymal stromal cells induce regulatory T cells via epigenetic conversion of human conventional CD4 T cells in vitro
RI Azevedo, E Minskaia, A Fernandes-Platzgummer, AIS Vieira, ...
Stem Cells 38 (8), 1007-1019, 2020
502020
Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia
TG Fernandes, MM Diogo, A Fernandes-Platzgummer, CL da Silva, ...
Stem Cell Research 5 (1), 76-89, 2010
492010
A fully-closed and automated hollow fiber bioreactor for clinical-grade manufacturing of human mesenchymal stem/stromal cells
A Mizukami, MS de Abreu Neto, F Moreira, A Fernandes-Platzgummer, ...
Stem cell reviews and reports 14, 141-143, 2018
362018
Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions
TG Fernandes, AM Fernandes-Platzgummer, CL Da Silva, MM Diogo, ...
Biotechnology letters 32, 171-179, 2010
312010
Scalable ex vivo expansion of human mesenchymal stem/stromal cells in microcarrier-based stirred culture systems
JG Carmelo, A Fernandes-Platzgummer, JMS Cabral, CL da Silva
Stem Cells and Good Manufacturing Practices: Methods, Protocols, and …, 2015
302015
Microcarrier culture systems for stem cell manufacturing
SM Badenes, A Fernandes-Platzgummer, CAV Rodrigues, MM Diogo, ...
Stem cell manufacturing, 77-104, 2016
272016
Clinical-grade manufacturing of therapeutic human mesenchymal stem/stromal cells in microcarrier-based culture systems
A Fernandes-Platzgummer, JG Carmelo, CL da Silva, JMS Cabral
Mesenchymal Stem Cells: Methods and Protocols, 375-388, 2016
242016
Maximizing mouse embryonic stem cell production in a stirred tank reactor by controlling dissolved oxygen concentration and continuous perfusion operation
A Fernandes-Platzgummer, MM Diogo, CL da Silva, JMS Cabral
Biochemical engineering journal 82, 81-90, 2014
232014
Addressing the manufacturing challenges of cell-based therapies
M de Almeida Fuzeta, AD de Matos Branco, A Fernandes-Platzgummer, ...
Current applications of pharmaceutical biotechnology, 225-278, 2020
212020
Modulation of the in vitro angiogenic potential of human mesenchymal stromal cells from different tissue sources
DS Pinto, T Ahsan, J Serra, A Fernandes‐Platzgummer, JMS Cabral, ...
Journal of Cellular Physiology 235 (10), 7224-7238, 2020
182020
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