| Noncompetitive allosteric inhibitors of the inflammatory chemokine receptors CXCR1 and CXCR2: prevention of reperfusion injury R Bertini, M Allegretti, C Bizzarri, A Moriconi, M Locati, G Zampella, ... Proceedings of the National Academy of Sciences 101 (32), 11791-11796, 2004 | 343 | 2004 |
| Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs) Effects of IL8 on MDSC C Alfaro, A Teijeira, C Oñate, G Pérez, MF Sanmamed, MP Andueza, ... Clinical Cancer Research 22 (15), 3924-3936, 2016 | 290 | 2016 |
| CXCR1 and CXCR2 chemokine receptor agonists produced by tumors induce neutrophil extracellular traps that interfere with immune cytotoxicity Á Teijeira, S Garasa, M Gato, C Alfaro, I Migueliz, A Cirella, C de Andrea, ... Immunity 52 (5), 856-871. e8, 2020 | 286 | 2020 |
| ELR+ CXC chemokines and their receptors (CXC chemokine receptor 1 and CXC chemokine receptor 2) as new therapeutic targets C Bizzarri, AR Beccari, R Bertini, MR Cavicchia, S Giorgini, M Allegretti Pharmacology & therapeutics 112 (1), 139-149, 2006 | 257 | 2006 |
| Phase II randomized, double-masked, vehicle-controlled trial of recombinant human nerve growth factor for neurotrophic keratitis S Bonini, A Lambiase, P Rama, F Sinigaglia, M Allegretti, W Chao, ... Ophthalmology 125 (9), 1332-1343, 2018 | 190* | 2018 |
| CXCR1/2 inhibition enhances pancreatic islet survival after transplantation A Citro, E Cantarelli, P Maffi, R Nano, R Melzi, A Mercalli, E Dugnani, ... The Journal of clinical investigation 122 (10), 3647-3651, 2012 | 153 | 2012 |
| LANCL2 is necessary for abscisic acid binding and signaling in human granulocytes and in rat insulinoma cells L Sturla, C Fresia, L Guida, S Bruzzone, S Scarfì, C Usai, F Fruscione, ... Journal of Biological Chemistry 284 (41), 28045-28057, 2009 | 148 | 2009 |
| Topical recombinant human nerve growth factor (cenegermin) for neurotrophic keratopathy: a multicenter randomized vehicle-controlled pivotal trial SC Pflugfelder, M Massaro-Giordano, VL Perez, P Hamrah, SX Deng, ... Ophthalmology 127 (1), 14-26, 2020 | 142 | 2020 |
| 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors M Allegretti, R Bertini, MC Cesta, C Bizzarri, R Di Bitondo, V Di Cioccio, ... Journal of medicinal chemistry 48 (13), 4312-4331, 2005 | 133 | 2005 |
| Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice A Zarbock, M Allegretti, K Ley British journal of pharmacology 155 (3), 357-364, 2008 | 121 | 2008 |
| Repertaxin, a novel inhibitor of rat CXCR2 function, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury DG Souza, R Bertini, AT Vieira, FQ Cunha, S Poole, M Allegretti, F Colotta, ... British journal of pharmacology 143 (1), 132-142, 2004 | 118 | 2004 |
| Treatment with DF 2162, a non‐competitive allosteric inhibitor of CXCR1/2, diminishes neutrophil influx and inflammatory hypernociception in mice TM Cunha, MM Barsante, AT Guerrero, WA Verri Jr, SH Ferreira, ... British journal of pharmacology 154 (2), 460-470, 2008 | 105 | 2008 |
| Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2 A Moriconi, MC Cesta, MN Cervellera, A Aramini, S Coniglio, S Colagioia, ... Journal of medicinal chemistry 50 (17), 3984-4002, 2007 | 104 | 2007 |
| Targeting C5a: recent advances in drug discovery M Allegretti, A Moriconi, AR Beccari, RD Bitondo, C Bizzarri, R Bertini, ... Current medicinal chemistry 12 (2), 217-236, 2005 | 99 | 2005 |
| Blockade of the chemokine receptor CXCR2 ameliorates adjuvant‐induced arthritis in rats MM Barsante, TM Cunha, M Allegretti, F Cattani, F Policani, C Bizzarri, ... British journal of pharmacology 153 (5), 992-1002, 2008 | 91 | 2008 |
| Current status of chemokine receptor inhibitors in development M Allegretti, MC Cesta, A Garin, AEI Proudfoot Immunology letters 145 (1-2), 68-78, 2012 | 75 | 2012 |
| Lactonization of Olefins Mediated by Mn (OAc) 3: A Sonochemical Approach. M Allegretti, A D'Annibale, C Trogolo Tetrahedron 49 (46), 10705-10714, 1993 | 74 | 1993 |
| CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice A Citro, A Valle, E Cantarelli, A Mercalli, S Pellegrini, D Liberati, ... Diabetes 64 (4), 1329-1340, 2015 | 67 | 2015 |
| Chemokine signaling in chemotherapy-induced neuropathic pain L Brandolini, M d’Angelo, A Antonosante, A Cimini, M Allegretti International journal of molecular sciences 20 (12), 2904, 2019 | 65 | 2019 |
| Carbocysteine lysine salt monohydrate (SCMC‐LYS) is a selective scavenger of reactive oxygen intermediates (ROIs) L Brandolini, M Allegretti, V Berdini, MN Cervellera, P Mascagni, ... European Cytokine Network 14 (1), 20-26, 2003 | 64 | 2003 |
