| Discovery and Characterization of SY-1365, a Selective, Covalent Inhibitor of CDK7 S Hu, JJ Marineau, N Rajagopal, KB Hamman, YJ Choi, DR Schmidt, ... Cancer research 79 (13), 3479-3491, 2019 | 117 | 2019 |
| Identification of cation-binding sites on actin that drive polymerization and modulate bending stiffness H Kang, MJ Bradley, BR McCullough, A Pierre, EE Grintsevich, E Reisler, ... Proceedings of the National Academy of Sciences 109 (42), 16923-16927, 2012 | 114 | 2012 |
| Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate X Wu, MJ Bradley, Y Cai, D Kümmel, EM De La Cruz, FA Barr, ... Proceedings of the National Academy of Sciences 108 (46), 18672-18677, 2011 | 111 | 2011 |
| Nickel-specific response in the transcriptional regulator, Escherichia coli NikR S Leitch, MJ Bradley, JL Rowe, PT Chivers, MJ Maroney Journal of the American Chemical Society 129 (16), 5085-5095, 2007 | 100 | 2007 |
| ATP utilization and RNA conformational rearrangement by DEAD-box proteins A Henn, MJ Bradley, EM De La Cruz Annual Review of Biophysics 41, 247-267, 2012 | 99 | 2012 |
| Molecular Dynamics Simulation of the< i> Escherichia coli</i> NikR Protein: Equilibrium Conformational Fluctuations Reveal Interdomain Allosteric Communication Pathways MJ Bradley, PT Chivers, NA Baker Journal of Molecular Biology 378 (5), 1155-1173, 2008 | 96 | 2008 |
| Mechanism of Mss116 ATPase reveals functional diversity of DEAD-box proteins W Cao, MM Coman, S Ding, A Henn, ER Middleton, MJ Bradley, ... Journal of Molecular Biology 409 (3), 399-414, 2011 | 79 | 2011 |
| Regulation of actin by ion-linked equilibria H Kang, MJ Bradley, WA Elam, M Enrique Biophysical journal 105 (12), 2621-2628, 2013 | 70 | 2013 |
| Site-specific cation release drives actin filament severing by vertebrate cofilin H Kang, MJ Bradley, W Cao, K Zhou, EE Grintsevich, A Michelot, ... Proceedings of the National Academy of Sciences 111 (50), 17821-17826, 2014 | 57 | 2014 |
| Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription JK Rimel, ZC Poss, B Erickson, ZL Maas, CC Ebmeier, JL Johnson, ... Genes & development 34 (21-22), 1452-1473, 2020 | 55 | 2020 |
| Cations stiffen actin filaments by adhering a key structural element to adjacent subunits GM Hocky, JL Baker, MJ Bradley, AV Sinitskiy, EM De La Cruz, GA Voth The Journal of Physical Chemistry B 120 (20), 4558-4567, 2016 | 46 | 2016 |
| Discovery of SY-5609: a selective, noncovalent inhibitor of CDK7 JJ Marineau, KB Hamman, S Hu, S Alnemy, J Mihalich, A Kabro, ... Journal of Medicinal Chemistry 65 (2), 1458-1480, 2021 | 43 | 2021 |
| Analyzing ATP Utilization by DEAD-Box RNA Helicases Using Kinetic and Equilibrium Methods MJ Bradley, M Enrique Methods in Enzymology 511, 29, 2012 | 24 | 2012 |
| Ligand‐induced changes in the conformational stability and flexibility of glutamate dehydrogenase and their role in catalysis and regulation SA Wacker, MJ Bradley, J Marion, E Bell Protein Science 19 (10), 1820-1829, 2010 | 22 | 2010 |
| Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics S Xia, M Wood, MJ Bradley, M Enrique, WH Konigsberg Nucleic Acids Research, 2013 | 15 | 2013 |
| Using physicochemical properties of amino acids to induce graphical models of residue couplings KSMT Hossain, C Bailey-Kellogg, AM Friedman, MJ Bradley, N Baker, ... Proceedings of the Tenth International Workshop on Data Mining in …, 2011 | 2 | 2011 |
| Surviving a bioscience Ph.D. - Mitigating the hurdles and pitfalls faced by doctoral students M Bradley ASBMB Today, 2012 | | 2012 |
| Why pursue a Ph.D. in the biosciences? MJ Bradley ASBMB Today, 2011 | | 2011 |
| Computational and experimental investigation of allosteric communication in the transcriptional regulator NikR MJ Bradley Washington University in St. Louis, 2009 | | 2009 |
Enrique M. De La CruzYale UniversityEmail confirmado em yale.edu
