| The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling C Ribas, P Penela, C Murga, A Salcedo, C García-Hoz, M Jurado-Pueyo, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (4), 913-922, 2007 | 501 | 2007 |
| A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho S Fukuhara, C Murga, M Zohar, T Igishi, JS Gutkind Journal of Biological Chemistry 274 (9), 5868-5879, 1999 | 483 | 1999 |
| Activation of Akt/Protein Kinase B by G protein-coupled receptors: a role for α and βγ subunits of heterotrimeric g proteins acting through phosphatidylinositol-3-OH kinaseγ C Murga, L Laguinge, R Wetzker, A Cuadrado, JS Gutkind Journal of Biological Chemistry 273 (30), 19080-19085, 1998 | 404 | 1998 |
| Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions: evidence for the association of phosphatidylinositol 3-kinase with the E … S Pece, M Chiariello, C Murga, JS Gutkind Journal of Biological Chemistry 274 (27), 19347-19351, 1999 | 356 | 1999 |
| The complex G protein‐coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets P Penela, C Murga, C Ribas, V Lafarga, F Mayor Jr British journal of pharmacology 160 (4), 821-832, 2010 | 259 | 2010 |
| A novel role for phosphatidylinositol 3-kinase β in signaling from G protein-coupled receptors to Akt C Murga, S Fukuhara, JS Gutkind Journal of Biological Chemistry 275 (16), 12069-12073, 2000 | 240 | 2000 |
| Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease P Penela, C Murga, C Ribas, AS Tutor, S Peregrín, F Mayor Jr Cardiovascular research 69 (1), 46-56, 2006 | 222 | 2006 |
| Rac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-κB C Murga, M Zohar, H Teramoto, JS Gutkind Oncogene 21 (2), 207-216, 2002 | 210 | 2002 |
| Functional roles of Akt signaling in mouse skin tumorigenesis C Segrelles, S Ruiz, P Perez, C Murga, M Santos, IV Budunova, ... Oncogene 21 (1), 53-64, 2002 | 207 | 2002 |
| Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK S Peregrin, M Jurado-Pueyo, PM Campos, V Sanz-Moreno, ... Current Biology 16 (20), 2042-2047, 2006 | 161 | 2006 |
| PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells Y Choi, J Zhang, C Murga, H Yu, E Koller, BP Monia, JS Gutkind, W Li Oncogene 21 (34), 5289-5300, 2002 | 134 | 2002 |
| G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits MC Jiménez-Sainz, C Murga, A Kavelaars, M Jurado-Pueyo, BF Krakstad, ... Molecular biology of the cell 17 (1), 25-31, 2006 | 129 | 2006 |
| Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1 P Singhmar, XJ Huo, N Eijkelkamp, SR Berciano, F Baameur, FC Mei, ... Proceedings of the National Academy of Sciences 113 (11), 3036-3041, 2016 | 123 | 2016 |
| G protein–coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity L Garcia-Guerra, I Nieto-Vazquez, R Vila-Bedmar, M Jurado-Pueyo, ... Diabetes 59 (10), 2407-2417, 2010 | 108 | 2010 |
| G protein-coupled receptor kinase 2 (GRK2) as a potential therapeutic target in cardiovascular and metabolic diseases C Murga, AC Arcones, M Cruces-Sande, AM Briones, M Salaices, ... Frontiers in pharmacology 10, 112, 2019 | 94 | 2019 |
| Regulation of G protein‐coupled receptor kinase 2 in brains of opiate‐treated rats and human opiate addicts A Ozaita, PV Escribá, P Ventayol, C Murga, F Mayor, JA García‐Sevilla Journal of neurochemistry 70 (3), 1249-1257, 1998 | 79 | 1998 |
| High affinity binding of β-Adrenergic receptor kinase to microsomal membranes: Modulation of the activity of bound kinase by heterotrimeric G protein activation C Murga, A Ruiz-Gómez, I García-Higuera, CM Kim, JL Benovic, ... Journal of Biological Chemistry 271 (2), 985-994, 1996 | 75 | 1996 |
| Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2 A Ruiz-Gómez, J Humrich, C Murga, U Quitterer, MJ Lohse, F Mayor Journal of Biological Chemistry 275 (38), 29724-29730, 2000 | 69 | 2000 |
| Interfering with MAP kinase docking interactions: implications and perspectives for the p38 route F Mayor, Jr, M Jurado-Pueyo, PM Campos, C Murga Cell Cycle 6 (5), 528-533, 2007 | 65 | 2007 |
| Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2 R Vila-Bedmar, M Cruces-Sande, E Lucas, HLDM Willemen, CJ Heijnen, ... Science signaling 8 (386), ra73-ra73, 2015 | 63 | 2015 |
