Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019 | 529 | 2019 |
Structure and allosteric inhibition of excitatory amino acid transporter 1 JC Canul-Tec, R Assal, E Cirri, P Legrand, S Brier, J Chamot-Rooke, ... Nature 544 (7651), 446-451, 2017 | 215 | 2017 |
Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen E Malito, A Faleri, P Lo Surdo, D Veggi, G Maruggi, E Grassi, E Cartocci, ... Proceedings of the National Academy of Sciences 110 (9), 3304-3309, 2013 | 148 | 2013 |
Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5 S Brier, D Lemaire, S DeBonis, E Forest, F Kozielski Biochemistry 43 (41), 13072-13082, 2004 | 146 | 2004 |
Molecular dissection of the inhibitor binding pocket of mitotic kinesin Eg5 reveals mutants that confer resistance to antimitotic agents S Brier, D Lemaire, S DeBonis, E Forest, F Kozielski Journal of molecular biology 360 (2), 360-376, 2006 | 74 | 2006 |
MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets V Hourdel, S Volant, DP O’Brien, A Chenal, J Chamot-Rooke, MA Dillies, ... Bioinformatics 32 (22), 3413-3419, 2016 | 69 | 2016 |
Transcriptional Regulation of the nadA Gene in Neisseria meningitidis Impacts the Prediction of Coverage of a Multicomponent Meningococcal Serogroup B Vaccine L Fagnocchi, A Biolchi, F Ferlicca, G Boccadifuoco, B Brunelli, S Brier, ... Infection and immunity 81 (2), 560-569, 2013 | 68 | 2013 |
Purification and characterization of pepsins A1 and A2 from the Antarctic rock cod Trematomus bernacchii S Brier, G Maria, V Carginale, A Capasso, Y Wu, RM Taylor, NB Borotto, ... The FEBS journal 274 (23), 6152-6166, 2007 | 63 | 2007 |
Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion DP O’brien, B Hernandez, D Durand, V Hourdel, AC Sotomayor-Pérez, ... Scientific reports 5 (1), 14223, 2015 | 54 | 2015 |
Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins K Hamdi, E Salladini, DP O’Brien, S Brier, A Chenal, I Yacoubi, S Longhi Scientific reports 7 (1), 15544, 2017 | 53 | 2017 |
Use of hydrogen/deuterium exchange mass spectrometry and mutagenesis as a tool to identify the binding region of inhibitors targeting the human mitotic kinesin Eg5 S Brier, D Lemaire, S DeBonis, F Kozielski, E Forest Rapid communications in mass spectrometry 20 (3), 456-462, 2006 | 51 | 2006 |
The Abl SH2‐kinase linker naturally adopts a conformation competent for SH3 domain binding S Chen, S Brier, TE Smithgall, JR Engen Protein science 16 (4), 572-581, 2007 | 42 | 2007 |
Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis DP O’Brien, D Durand, A Voegele, V Hourdel, M Davi, J Chamot-Rooke, ... PLoS biology 15 (12), e2004486, 2017 | 39 | 2017 |
Two cross‐reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties A Faleri, L Santini, S Brier, W Pansegrau, PL Surdo, M Scarselli, ... The FASEB Journal 28 (4), 1644-1653, 2014 | 38 | 2014 |
Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex S Brier, D Pflieger, M Le Mignon, I Bally, C Gaboriaud, GJ Arlaud, ... Journal of biological chemistry 285 (42), 32251-32263, 2010 | 34 | 2010 |
Post‐translational acylation controls the folding and functions of the CyaA RTX toxin DP O'Brien, SE Cannella, A Voegele, D Raoux‐Barbot, M Davi, T Douche, ... The FASEB Journal 33 (9), 10065-10076, 2019 | 30 | 2019 |
Molecular basis of ligand-dependent regulation of NadR, the transcriptional repressor of meningococcal virulence factor NadA A Liguori, E Malito, P Lo Surdo, L Fagnocchi, F Cantini, AF Haag, S Brier, ... PLoS pathogens 12 (4), e1005557, 2016 | 26 | 2016 |
Structural characterization of whirlin reveals an unexpected and dynamic supramodule conformation of its PDZ tandem F Delhommel, F Cordier, B Bardiaux, G Bouvier, B Colcombet-Cazenave, ... Structure 25 (11), 1645-1656. e5, 2017 | 24 | 2017 |
Consensus designs and thermal stability determinants of a human glutamate transporter E Cirri, S Brier, R Assal, JC Canul-Tec, J Chamot-Rooke, N Reyes Elife 7, e40110, 2018 | 23 | 2018 |
Structural insight into the mechanism of DNA-binding attenuation of the Neisserial adhesin repressor NadR by the small natural ligand 4-hydroxyphenylacetic acid S Brier, L Fagnocchi, D Donnarumma, M Scarselli, R Rappuoli, M Nissum, ... Biochemistry 51 (34), 6738-6752, 2012 | 23 | 2012 |