Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer Z Zhang, JC Lee, L Lin, V Olivas, V Au, T LaFramboise, M Abdel-Rahman, ... Nature genetics 44 (8), 852-860, 2012 | 1303 | 2012 |
High-throughput oncogene mutation profiling in human cancer RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ... Nature genetics 39 (3), 347-351, 2007 | 1170 | 2007 |
Single nucleotide polymorphism arrays: a decade of biological, computational and technological advances T LaFramboise Nucleic acids research 37 (13), 4181-4193, 2009 | 628 | 2009 |
Dynamics of clonal evolution in myelodysplastic syndromes H Makishima, T Yoshizato, K Yoshida, MA Sekeres, T Radivoyevitch, ... Nature genetics 49 (2), 204-212, 2017 | 448 | 2017 |
Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing RK Thomas, E Nickerson, JF Simons, PA Jänne, T Tengs, Y Yuza, ... Nature medicine 12 (7), 852-855, 2006 | 433 | 2006 |
Integrative eQTL-based analyses reveal the biology of breast cancer risk loci Q Li, JH Seo, B Stranger, A McKenna, I Pe’Er, T LaFramboise, M Brown, ... Cell 152 (3), 633-641, 2013 | 390 | 2013 |
Epigenomic enhancer profiling defines a signature of colon cancer B Akhtar-Zaidi, R Cowper-Sal· lari, O Corradin, A Saiakhova, CF Bartels, ... Science 336 (6082), 736-739, 2012 | 377 | 2012 |
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis X Zhao, BA Weir, T LaFramboise, M Lin, R Beroukhim, L Garraway, ... Cancer research 65 (13), 5561-5570, 2005 | 367 | 2005 |
Comparative analysis of algorithms for next-generation sequencing read alignment M Ruffalo, T LaFramboise, M Koyutürk Bioinformatics 27 (20), 2790-2796, 2011 | 359 | 2011 |
Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions ML Sos, K Michel, T Zander, J Weiss, P Frommolt, M Peifer, D Li, R Ullrich, ... The Journal of clinical investigation 119 (6), 1727-1740, 2009 | 325 | 2009 |
CHD7 targets active gene enhancer elements to modulate ES cell-specific gene expression MP Schnetz, L Handoko, B Akhtar-Zaidi, CF Bartels, CF Pereira, ... PLoS genetics 6 (7), e1001023, 2010 | 275 | 2010 |
Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns MP Schnetz, CF Bartels, K Shastri, D Balasubramanian, GE Zentner, ... Genome research 19 (4), 590-601, 2009 | 267 | 2009 |
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer Y Hao, Y Samuels, Q Li, D Krokowski, BJ Guan, C Wang, Z Jin, B Dong, ... Nature communications 7 (1), 11971, 2016 | 258 | 2016 |
Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells Z Zhang, S Kobayashi, AC Borczuk, RS Leidner, T LaFramboise, ... Carcinogenesis 31 (4), 577-586, 2010 | 216 | 2010 |
Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett’s esophagus HR Moinova, T LaFramboise, JD Lutterbaugh, AK Chandar, J Dumot, ... Science translational medicine 10 (424), eaao5848, 2018 | 158 | 2018 |
The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors O Rozenblatt-Rosen, T Nagaike, JM Francis, S Kaneko, KA Glatt, ... Proceedings of the National Academy of Sciences 106 (3), 755-760, 2009 | 149 | 2009 |
Allele-specific amplification in cancer revealed by SNP array analysis T LaFramboise, BA Weir, X Zhao, R Beroukhim, C Li, D Harrington, ... PLoS Computational Biology 1 (6), e65, 2005 | 139 | 2005 |
The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272 Y Minami, T Shimamura, K Shah, T LaFramboise, KA Glatt, E Liniker, ... Oncogene 26 (34), 5023-5027, 2007 | 125 | 2007 |
Epitope tagging of endogenous proteins for genome-wide ChIP-chip studies X Zhang, C Guo, Y Chen, HP Shulha, MP Schnetz, T LaFramboise, ... Nature methods 5 (2), 163-165, 2008 | 122 | 2008 |
Genomic determinants of chronic myelomonocytic leukemia BJ Patel, B Przychodzen, S Thota, T Radivoyevitch, V Visconte, ... Leukemia 31 (12), 2815-2823, 2017 | 104 | 2017 |