Rui O. Costa
Rui O. Costa
Center for neuroscience and Cell Biology
Email confirmado em cnc.uc.pt
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An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity
E Ferreiro, R Resende, R Costa, CR Oliveira, CMF Pereira
Neurobiology of disease 23 (3), 669-678, 2006
2292006
Mitochondrial-and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers
E Ferreiro, I Baldeiras, IL Ferreira, RO Costa, AC Rego, CF Pereira, ...
International Journal of Cell Biology 2012, 2012
1272012
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease
SI Mota, RO Costa, IL Ferreira, I Santana, GL Caldeira, C Padovano, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (7 …, 2015
1162015
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N‐methyl‐D‐aspartate receptor in mature hippocampal cultures treated with amyloid‐β …
RO Costa, PN Lacor, IL Ferreira, R Resende, YP Auberson, WL Klein, ...
Aging cell 11 (5), 823-833, 2012
872012
ER stress-mediated apoptotic pathway induced by Aβ peptide requires the presence of functional mitochondria
RO Costa, E Ferreiro, SM Cardoso, CR Oliveira, CMF Pereira
Journal of Alzheimer's Disease 20 (2), 625-636, 2010
772010
Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.
RO Costa, E Ferreiro, I Martins, I Santana, SM Cardoso, CR Oliveira, ...
Neurobiology of aging, 2011
662011
Involvement of mitochondria in endoplasmic reticulum stress‐induced apoptotic cell death pathway triggered by the prion peptide PrP106–126
E Ferreiro, R Costa, S Marques, SM Cardoso, CR Oliveira, CMF Pereira
Journal of neurochemistry 104 (3), 766-776, 2008
592008
Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers
I Martins, S Gomes, RO Costa, L Otvos, CR Oliveira, R Resende, ...
Neuroscience 241, 41-51, 2013
422013
Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons
RO Costa, E Ferreiro, CR Oliveira, CMF Pereira
Molecular and Cellular Neuroscience 52, 1-8, 2013
372013
Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF
LF Martins, RO Costa, JR Pedro, P Aguiar, SC Serra, FG Teixeira, ...
Scientific reports 7 (1), 1-13, 2017
362017
PROneurotrophins and CONSequences
RO Costa, T Perestrelo, RD Almeida
Molecular neurobiology 55 (4), 2934-2951, 2018
182018
The RNA Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons
G Leal, D Comprido, P de Luca, E Morais, L Rodrigues, M Mele, ...
Eneuro, 2017
142017
Visualizing K48 ubiquitination during presynaptic formation by ubiquitination-induced fluorescence complementation (UiFC)
MJ Pinto, JR Pedro, RO Costa, RD Almeida
Frontiers in Molecular Neuroscience 9, 43, 2016
122016
Alterations in GABAA-receptor trafficking and synaptic dysfunction in brain disorders
M Mele, RO Costa, CB Duarte
Frontiers in Cellular Neuroscience 13, 77, 2019
92019
Synaptogenesis stimulates a proteasome-mediated ribosome reduction in axons
RO Costa, H Martins, LF Martins, AW Cwetsch, M Mele, JR Pedro, ...
Cell reports 28 (4), 864-876. e6, 2019
22019
Role of endoplasmic reticulum-mediated apoptotic pathway in Ab toxicity
E Ferreiro, R Costa, S Marques, CR Oliveira, C Pereira
Cognitive Sciences at the Leading Edge, 2007
12007
Isolation and Culture of Chick Ciliary Ganglion Neurons
FJ Costa, MS Dias, RO Costa, JR Pedro, RD Almeida
Journal of Visualized Experiments: Jove, 2020
2020
A Microfluidic Culture Platform for Neurotrophin Signaling Studies
RO Costa, T Perestrelo, D Tomé, RD Almeida
Brain-Derived Neurotrophic Factor (BDNF), 185-201, 2018
2018
Alzheimers disease-associated amyloide peptide oligomers induce endoplasmic reticulum stress throught N-Methyl-D-Aspartate receptors in hippocampal neurons
RO Costa, PN Lacor, WL Klein, AC Rego, C Pereira
FENS 2010, FENS Abstr. vol 5, 078.18, 2010
2010
Communication between endoplamic reticulum and mitochondria in the neuronal death induced by amyloid-beta peptide
E Ferreiro, R Costa, R Resende, S Marques, S Cardoso, CR Oliveira, ...
Journal of the Neurological Sciences 1 (283), 280-281, 2009
2009
O sistema não pode efectuar a operação agora. Tente novamente mais tarde.
Artigos 1–20