Rui O. Costa
Rui O. Costa
Center for neuroscience and Cell Biology
Email confirmado em cnc.uc.pt
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An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity
E Ferreiro, R Resende, R Costa, CR Oliveira, CMF Pereira
Neurobiology of disease 23 (3), 669-678, 2006
2312006
Mitochondrial-and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers
E Ferreiro, I Baldeiras, IL Ferreira, RO Costa, AC Rego, CF Pereira, ...
International Journal of Cell Biology 2012, 2012
1312012
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer's disease
SI Mota, RO Costa, IL Ferreira, I Santana, GL Caldeira, C Padovano, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (7 …, 2015
1282015
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N‐methyl‐D‐aspartate receptor in mature hippocampal cultures treated with amyloid‐β …
RO Costa, PN Lacor, IL Ferreira, R Resende, YP Auberson, WL Klein, ...
Aging cell 11 (5), 823-833, 2012
872012
ER stress-mediated apoptotic pathway induced by Aβ peptide requires the presence of functional mitochondria
RO Costa, E Ferreiro, SM Cardoso, CR Oliveira, CMF Pereira
Journal of Alzheimer's Disease 20 (2), 625-636, 2010
792010
Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions.
RO Costa, E Ferreiro, I Martins, I Santana, SM Cardoso, CR Oliveira, ...
Neurobiology of aging, 2011
672011
Involvement of mitochondria in endoplasmic reticulum stress‐induced apoptotic cell death pathway triggered by the prion peptide PrP106–126
E Ferreiro, R Costa, S Marques, SM Cardoso, CR Oliveira, CMF Pereira
Journal of neurochemistry 104 (3), 766-776, 2008
592008
Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF
LF Martins, RO Costa, JR Pedro, P Aguiar, SC Serra, FG Teixeira, ...
Scientific reports 7 (1), 1-13, 2017
432017
Leptin and ghrelin prevent hippocampal dysfunction induced by Aβ oligomers
I Martins, S Gomes, RO Costa, L Otvos, CR Oliveira, R Resende, ...
Neuroscience 241, 41-51, 2013
432013
Inhibition of mitochondrial cytochrome c oxidase potentiates Aβ-induced ER stress and cell death in cortical neurons
RO Costa, E Ferreiro, CR Oliveira, CMF Pereira
Molecular and Cellular Neuroscience 52, 1-8, 2013
392013
Alterations in GABAA-receptor trafficking and synaptic dysfunction in brain disorders
M Mele, RO Costa, CB Duarte
Frontiers in cellular neuroscience 13, 77, 2019
192019
PROneurotrophins and CONSequences
RO Costa, T Perestrelo, RD Almeida
Molecular neurobiology 55 (4), 2934-2951, 2018
192018
The RNA-binding protein hnRNP K mediates the effect of BDNF on dendritic mRNA metabolism and regulates synaptic NMDA receptors in hippocampal neurons
G Leal, D Comprido, P de Luca, E Morais, L Rodrigues, M Mele, ...
Eneuro 4 (6), 2017
182017
Visualizing K48 ubiquitination during presynaptic formation by ubiquitination-induced fluorescence complementation (UiFC)
MJ Pinto, JR Pedro, RO Costa, RD Almeida
Frontiers in molecular neuroscience 9, 43, 2016
132016
Synaptogenesis stimulates a proteasome-mediated ribosome reduction in axons
RO Costa, H Martins, LF Martins, AW Cwetsch, M Mele, JR Pedro, ...
Cell reports 28 (4), 864-876. e6, 2019
52019
Role of endoplasmic reticulum-mediated apoptotic pathway in Ab toxicity
E Ferreiro, R Costa, S Marques, CR Oliveira, C Pereira
Cognitive Sciences at the Leading Edge, 2007
12007
A Microfluidic Culture Platform for Neurotrophin Signaling Studies
RO Costa, T Perestrelo, D Tomé, RD Almeida
Brain-Derived Neurotrophic Factor (BDNF), 185-201, 2018
2018
Isolation and Culture of Chick Ciliary Ganglion Neurons
FJ Costa, MS Dias, RO Costa, JR Pedro, RD Almeida
MyJoVE Corporation, 2016
2016
Alzheimers disease-associated amyloide peptide oligomers induce endoplasmic reticulum stress throught N-Methyl-D-Aspartate receptors in hippocampal neurons
RO Costa, PN Lacor, WL Klein, AC Rego, C Pereira
FENS 2010, FENS Abstr. vol 5, 078.18, 2010
2010
Communication between endoplamic reticulum and mitochondria in the neuronal death induced by amyloid-beta peptide
E Ferreiro, R Costa, R Resende, S Marques, S Cardoso, CR Oliveira, ...
Journal of the Neurological Sciences 1 (283), 280-281, 2009
2009
O sistema não pode efectuar a operação agora. Tente novamente mais tarde.
Artigos 1–20