Patient-specific induced pluripotent stem-cell models for long-QT syndrome A Moretti, M Bellin, A Welling, CB Jung, JT Lam, L Bott-Flügel, T Dorn, ... New England Journal of Medicine 363 (15), 1397-1409, 2010 | 1436 | 2010 |
Induced pluripotent stem cells: the new patient? M Bellin, MC Marchetto, FH Gage, CL Mummery Nature reviews Molecular cell biology 13 (11), 713-726, 2012 | 572 | 2012 |
Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease E Giacomelli, V Meraviglia, G Campostrini, A Cochrane, X Cao, ... Cell stem cell 26 (6), 862-879. e11, 2020 | 412 | 2020 |
Dantrolene rescues arrhythmogenic RYR2 defect in a patient‐specific stem cell model of catecholaminergic polymorphic ventricular tachycardia CB Jung, A Moretti, M Mederos y Schnitzler, L Iop, U Storch, M Bellin, ... EMBO molecular medicine 4 (3), 180-191, 2012 | 371 | 2012 |
Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem? CC Veerman, G Kosmidis, CL Mummery, S Casini, AO Verkerk, M Bellin Stem cells and development 24 (9), 1035-1052, 2015 | 303 | 2015 |
Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells E Giacomelli, M Bellin, L Sala, BJ Van Meer, LGJ Tertoolen, VV Orlova, ... Development 144 (6), 1008-1017, 2017 | 301 | 2017 |
MUSCLEMOTION: a versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo L Sala, BJ Van Meer, LGJ Tertoolen, J Bakkers, M Bellin, RP Davis, ... Circulation research 122 (3), e5-e16, 2018 | 275 | 2018 |
Isogenic human pluripotent stem cell pairs reveal the role of a KCNH2 mutation in long‐QT syndrome M Bellin, S Casini, RP Davis, C D'aniello, J Haas, D Ward‐van Oostwaard, ... The EMBO journal 32 (24), 3161-3175, 2013 | 265 | 2013 |
Functional maturation of human pluripotent stem cell derived cardiomyocytes in vitro–correlation between contraction force and electrophysiology MC Ribeiro, LG Tertoolen, JA Guadix, M Bellin, G Kosmidis, C D'Aniello, ... Biomaterials 51, 138-150, 2015 | 249 | 2015 |
Expansion and patterning of cardiovascular progenitors derived from human pluripotent stem cells MJ Birket, MC Ribeiro, AO Verkerk, D Ward, AR Leitoguinho, ... Nature biotechnology 33 (9), 970-979, 2015 | 239 | 2015 |
Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue M Zhang, C D’Aniello, AO Verkerk, E Wrobel, S Frank, ... Proceedings of the National Academy of Sciences 111 (50), E5383-E5392, 2014 | 198 | 2014 |
Mouse and human induced pluripotent stem cells as a source for multipotent Isl1+ cardiovascular progenitors A Moretti, M Bellin, CB Jung, TM Thies, Y Takashima, A Bernshausen, ... The FASEB Journal 24 (3), 700-711, 2010 | 154 | 2010 |
Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come? L Sala, M Bellin, CL Mummery British journal of pharmacology 174 (21), 3749-3765, 2017 | 134 | 2017 |
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin X Qiao, SY van der Zanden, DPA Wander, DM Borràs, JY Song, X Li, ... Proceedings of the National Academy of Sciences 117 (26), 15182-15192, 2020 | 124 | 2020 |
Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes Z Chen, W Xian, M Bellin, T Dorn, Q Tian, A Goedel, L Dreizehnter, ... European Heart Journal 38 (4), 292-301, 2017 | 101 | 2017 |
A new hERG allosteric modulator rescues genetic and drug‐induced long‐QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells L Sala, Z Yu, D Ward‐van Oostwaard, JPD van Veldhoven, A Moretti, ... EMBO molecular medicine 8 (9), 1065-1081, 2016 | 92 | 2016 |
Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes E Giacomelli, CL Mummery, M Bellin Cellular and molecular life sciences 74, 3711-3739, 2017 | 67 | 2017 |
Human pluripotent stem cell differentiation into functional epicardial progenitor cells JA Guadix, VV Orlova, E Giacomelli, M Bellin, MC Ribeiro, CL Mummery, ... Stem Cell Reports 9 (6), 1754-1764, 2017 | 66 | 2017 |
Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel H Zhang, B Zou, H Yu, A Moretti, X Wang, W Yan, JJ Babcock, M Bellin, ... Proceedings of the National Academy of Sciences 109 (29), 11866-11871, 2012 | 63 | 2012 |
Altered glucose metabolism and proteolysis in pancreatic cancer cell conditioned myoblasts: searching for a gene expression pattern with a microarray analysis of 5000 skeletal … D Basso, C Millino, E Greco, C Romualdi, P Fogar, A Valerio, M Bellin, ... Gut 53 (8), 1159-1166, 2004 | 61 | 2004 |