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Ana Ledo
Ana Ledo
University of Coimbra Faculty of Pharmacy and Center for Neuroscience and Cell Biology
Verified email at ff.uc.pt
Title
Cited by
Cited by
Year
Electrochemical measurement of endogenously produced nitric oxide in brain slices using Nafion/o-phenylenediamine modified carbon fiber microelectrodes
NR Ferreira, A Ledo, JG Frade, GA Gerhardt, J Laranjinha, RM Barbosa
Analytica Chimica Acta 535 (1-2), 1-7, 2005
1102005
Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor
A Ledo, RM Barbosa, GA Gerhardt, E Cadenas, J Laranjinha
Proceedings of the National Academy of Sciences 102 (48), 17483-17488, 2005
1092005
Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions
A Ledo, J Frade, RM Barbosa, J Laranjinha
Molecular aspects of medicine 25 (1-2), 75-89, 2004
932004
Neurovascular-neuroenergetic coupling axis in the brain: master regulation by nitric oxide and consequences in aging and neurodegeneration
CF Lourenço, A Ledo, RM Barbosa, J Laranjinha
Free Radical Biology and Medicine 108, 668-682, 2017
882017
Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling
CF Lourenço, A Ledo, RM Barbosa, J Laranjinha
Experimental neurology 291, 36-43, 2017
802017
Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegeneration
RM Santos, CF Lourenço, A Ledo, RM Barbosa, J Laranjinha
International Journal of Cell Biology 2012, 2012
562012
Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling
J Laranjinha, RM Santos, CF Lourenço, A Ledo, RM Barbosa
Annals of the New York Academy of Sciences 1259 (1), 10-18, 2012
462012
Neurovascular and neurometabolic derailment in aging and Alzheimer's disease
CF Lourenço, A Ledo, C Dias, RM Barbosa, J Laranjinha
Frontiers in aging neuroscience 7, 103, 2015
442015
Age-dependent impairment of neurovascular and neurometabolic coupling in the hippocampus
CF Lourenço, A Ledo, M Caetano, RM Barbosa, J Laranjinha
Frontiers in Physiology 9, 390136, 2018
412018
Simultaneous measurements of ascorbate and glutamate in vivo in the rat brain using carbon fiber nanocomposite sensors and microbiosensor arrays
NR Ferreira, A Ledo, J Laranjinha, GA Gerhardt, RM Barbosa
Bioelectrochemistry 121, 142-150, 2018
402018
Microelectrode array biosensor for high-resolution measurements of extracellular glucose in the brain
CF Lourenço, A Ledo, J Laranjinha, GA Gerhardt, RM Barbosa
Sensors and Actuators B: Chemical 237, 298-307, 2016
392016
Neurometabolic and electrophysiological changes during cortical spreading depolarization: Multimodal approach based on a lactate-glucose dual microbiosensor arrays
CF Lourenço, A Ledo, GA Gerhardt, J Laranjinha, RM Barbosa
Scientific reports 7 (1), 6764, 2017
382017
Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation
C Dias, CF Lourenço, E Ferreiro, RM Barbosa, J Laranjinha, A Ledo
Neurobiology of Aging 46, 84-95, 2016
372016
Ceramic-based multisite platinum microelectrode arrays: morphological characteristics and electrochemical performance for extracellular oxygen measurements in brain tissue
A Ledo, CF Lourenco, J Laranjinha, CMA Brett, GA Gerhardt, RM Barbosa
Analytical chemistry 89 (3), 1674-1683, 2017
332017
Dynamic and interacting profiles of⋅ NO and O2 in rat hippocampal slices
A Ledo, R Barbosa, E Cadenas, J Laranjinha
Free Radical Biology and Medicine 48 (8), 1044-1050, 2010
292010
Nitric oxide monitoring in hippocampal brain slices using electrochemical methods
A Ledo, RM Barbosa, J Frade, J Laranjinha
Methods in enzymology 359, 111-125, 2002
282002
Combined in vivo amperometric oximetry and electrophysiology in a single sensor: A tool for epilepsy research
A Ledo, CF Lourenço, J Laranjinha, GA Gerhardt, RM Barbosa
Analytical chemistry 89 (22), 12383-12390, 2017
272017
In vivo hydrogen peroxide diffusivity in brain tissue supports volume signaling activity
A Ledo, E Fernandes, A Salvador, J Laranjinha, RM Barbosa
Redox Biology 50, 102250, 2022
262022
Preparation, standardization and measurement of nitric oxide solutions
RM Barbosaa, AJL Jesusb, RM Santosa, CL Pereiraa, CF Marquesa, ...
Global Journal of Analytical Chemistry| Volume 2 (6), 2011
232011
The bioactivity of neuronal-derived nitric oxide in aging and neurodegeneration: Switching signaling to degeneration
A Ledo, CF Lourenço, E Cadenas, RM Barbosa, J Laranjinha
Free Radical Biology and Medicine 162, 500-513, 2021
212021
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