| Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) N Mavaddat, D Barrowdale, IL Andrulis, SM Domchek, D Eccles, ... Cancer Epidemiology, Biomarkers & Prevention 21 (1), 134-147, 2012 | 775 | 2012 |
| Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ... Nature genetics 49 (5), 680-691, 2017 | 423 | 2017 |
| Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017 | 373 | 2017 |
| Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk FJ Couch, X Wang, L McGuffog, A Lee, C Olswold, KB Kuchenbaecker, ... PLoS genetics 9 (3), e1003212, 2013 | 332 | 2013 |
| Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers KB Kuchenbaecker, L McGuffog, D Barrowdale, A Lee, P Soucy, J Dennis, ... JNCI: Journal of the National Cancer Institute 109 (7), djw302, 2017 | 327 | 2017 |
| Identification of six new susceptibility loci for invasive epithelial ovarian cancer KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ... Nature genetics 47 (2), 164-171, 2015 | 311 | 2015 |
| POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance F Bellido, M Pineda, G Aiza, R Valdés-Mas, M Navarro, DA Puente, ... Genetics in Medicine 18 (4), 325-332, 2016 | 270 | 2016 |
| Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells JA Menendez, A Vazquez-Martin, R Colomer, J Brunet, ... BMC cancer 7, 1-19, 2007 | 231 | 2007 |
| Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells A Vazquez‐Martin, R Colomer, J Brunet, R Lupu, JA Menendez Cell proliferation 41 (1), 59-85, 2008 | 228 | 2008 |
| New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis L Valle, E Hernández-Illán, F Bellido, G Aiza, A Castillejo, MI Castillejo, ... Human molecular genetics 23 (13), 3506-3512, 2014 | 191 | 2014 |
| Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores J Lecarpentier, V Silvestri, KB Kuchenbaecker, D Barrowdale, J Dennis, ... Journal of Clinical Oncology 35 (20), 2240-2250, 2017 | 190 | 2017 |
| Clinical portrait of the SARS-CoV-2 epidemic in European patients with cancer DJ Pinato, A Zambelli, J Aguilar-Company, M Bower, CCT Sng, R Salazar, ... Cancer discovery 10 (10), 1465-1474, 2020 | 173 | 2020 |
| Early onset hereditary papillary renal carcinoma: germline missense mutations in the tyrosine kinase domain of the met proto-oncogene LS Schmidt, ML Nickerson, D Angeloni, GM Glenn, MCM Walther, ... The Journal of urology 172 (4 Part 1), 1256-1261, 2004 | 171 | 2004 |
| Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 AM Dunning, K Michailidou, KB Kuchenbaecker, D Thompson, JD French, ... Nature genetics 48 (4), 374-386, 2016 | 158 | 2016 |
| Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis X Zhang, HC Chiang, Y Wang, C Zhang, S Smith, X Zhao, SJ Nair, ... Nature communications 8 (1), 15908, 2017 | 156 | 2017 |
| Prevalence of BRCA1 and BRCA2 germline mutations in young breast cancer patients: A population‐based study S de Sanjosé, M Leone, V Berez, A Izquierdo, R Font, JM Brunet, T Louat, ... International Journal of Cancer 106 (4), 588-593, 2003 | 151 | 2003 |
| Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75 T Puig, A Vázquez-Martín, J Relat, J Pétriz, JA Menéndez, R Porta, ... Breast cancer research and treatment 109, 471-479, 2008 | 137 | 2008 |
| Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer CA Maxwell, J Benítez, L Gómez-Baldó, A Osorio, N Bonifaci, ... PLoS biology 9 (11), e1001199, 2011 | 136 | 2011 |
| Large scale multifactorial likelihood quantitative analysis of BRCA1 and BRCA2 variants: An ENIGMA resource to support clinical variant classification MT Parsons, E Tudini, H Li, E Hahnen, B Wappenschmidt, L Feliubadaló, ... Human mutation 40 (9), 1557-1578, 2019 | 126 | 2019 |
| Next-generation sequencing meets genetic diagnostics: development of a comprehensive workflow for the analysis of BRCA1 and BRCA2 genes L Feliubadaló, A Lopez-Doriga, E Castellsagué, J Del Valle, M Menéndez, ... European Journal of Human Genetics 21 (8), 864-870, 2013 | 126 | 2013 |
