| Dynamic protein acylation: new substrates, mechanisms, and drug targets T Lanyon-Hogg, M Faronato, RA Serwa, EW Tate Trends in biochemical sciences 42 (7), 566-581, 2017 | 128 | 2017 |
| Global profiling of protein lipidation using chemical proteomic technologies EW Tate, KA Kalesh, T Lanyon-Hogg, EM Storck, E Thinon Current opinion in chemical biology 24, 48-57, 2015 | 111 | 2015 |
| Getting a camel through the eye of a needle: the import of folded proteins by peroxisomes T Lanyon‐Hogg, SL Warriner, A Baker Biology of the Cell 102 (4), 245-263, 2010 | 102 | 2010 |
| Dual chemical probes enable quantitative system-wide analysis of protein prenylation and prenylation dynamics EM Storck, J Morales-Sanfrutos, RA Serwa, N Panyain, T Lanyon-Hogg, ... Nature Chemistry 11 (6), 552-561, 2019 | 94 | 2019 |
| Topological analysis of Hedgehog acyltransferase, a multipalmitoylated transmembrane protein AD Konitsiotis, B Jovanović, P Ciepla, M Spitaler, T Lanyon-Hogg, ... Journal of Biological Chemistry 290 (6), 3293-3307, 2015 | 62 | 2015 |
| Discovery of a potent and selective covalent inhibitor and activity-based probe for the deubiquitylating enzyme UCHL1, with antifibrotic activity N Panyain, A Godinat, T Lanyon-Hogg, S Lachiondo-Ortega, EJ Will, ... Journal of the American Chemical Society 142 (28), 12020-12026, 2020 | 59 | 2020 |
| Peroxisome protein import: a complex journey A Baker, TL Hogg, SL Warriner Biochemical Society Transactions 44 (3), 783-789, 2016 | 49 | 2016 |
| Characterization of Hedgehog acyltransferase inhibitors identifies a small molecule probe for Hedgehog signaling by cancer cells UR Rodgers, T Lanyon-Hogg, N Masumoto, M Ritzefeld, R Burke, J Blagg, ... ACS chemical biology 11 (12), 3256-3262, 2016 | 46 | 2016 |
| Synthesis of Small Molecules with High Scaffold Diversity: Exploitation of Metathesis Cascades in Combination with Inter‐and Intramolecular Diels–Alder Reactions C O'Leary‐Steele, PJ Pedersen, T James, T Lanyon‐Hogg, S Leach, ... Chemistry–A European Journal 16 (31), 9563-9571, 2010 | 42 | 2010 |
| Membrane bound O-acyltransferases and their inhibitors. N Masumoto, T Lanyon-Hogg, UR Rodgers, AD Konitsiotis, AI Magee, ... Biochemical Society Transactions 43 (2), 2015 | 41 | 2015 |
| Structure, mechanism, and inhibition of Hedgehog acyltransferase CE Coupland, SA Andrei, TB Ansell, L Carrique, P Kumar, L Sefer, ... Molecular cell 81 (24), 5025-5038. e10, 2021 | 33 | 2021 |
| Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane JA Clulow, EM Storck, T Lanyon-Hogg, KA Kalesh, LH Jones, EW Tate Chemical communications 53 (37), 5182-5185, 2017 | 31 | 2017 |
| Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase T Lanyon-Hogg, N Masumoto, G Bodakh, AD Konitsiotis, E Thinon, ... Analytical biochemistry 490, 66-72, 2015 | 27 | 2015 |
| PEX14 binding to Arabidopsis PEX5 has differential effects on PTS1 and PTS2 cargo occupancy of the receptor T Lanyon-Hogg, J Hooper, S Gunn, SL Warriner, A Baker FEBS letters 588 (14), 2223-2229, 2014 | 27 | 2014 |
| Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes T Lanyon-Hogg, M Ritzefeld, L Sefer, JK Bickel, AF Rudolf, N Panyain, ... Chemical Science 10 (39), 8995-9000, 2019 | 26 | 2019 |
| Proteome-wide analysis of protein lipidation using chemical probes: in-gel fluorescence visualization, identification and quantification of N-myristoylation, N-and S-acylation … WW Kallemeijn, T Lanyon-Hogg, N Panyain, A Goya Grocin, P Ciepla, ... Nature Protocols 16 (11), 5083-5122, 2021 | 25 | 2021 |
| Identification of a potent small-molecule inhibitor of bacterial DNA repair that potentiates quinolone antibiotic activity in methicillin-resistant Staphylococcus aureus CSQ Lim, KP Ha, RS Clarke, LA Gavin, DT Cook, JA Hutton, CL Sutherell, ... Bioorganic & Medicinal Chemistry 27 (20), 114962, 2019 | 25 | 2019 |
| Modulation of Amide Bond Rotamers in 5-Acyl-6,7-dihydrothieno[3,2-c]pyridines T Lanyon-Hogg, M Ritzefeld, N Masumoto, AI Magee, HS Rzepa, EW Tate The Journal of Organic Chemistry 80 (9), 4370-4377, 2015 | 24 | 2015 |
| Photochemical probe identification of a small‐molecule inhibitor binding site in Hedgehog acyltransferase (HHAT) T Lanyon-Hogg, M Ritzefeld, L Zhang, B Pogranyi, M Mondal, L Sefer, ... Angewandte Chemie International Edition, 2021 | 19 | 2021 |
| Direct targeting of the Ras GTPase superfamily through structure-based design W Zhao, M Jamshidiha, T Lanyon-Hogg, C Recchi, E Cota, E W Tate Current topics in medicinal chemistry 17 (1), 16-29, 2017 | 19 | 2017 |
Edward W. TateImperial College London & Francis Crick InstituteVerified email at imperial.ac.uk
