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Laurence J Young
Laurence J Young
Saber Bio
Email confirmado em fluidic.com
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Temperature treatment of highly porous zirconium-containing metal–organic frameworks extends drug delivery release
MH Teplensky, M Fantham, P Li, TC Wang, JP Mehta, LJ Young, ...
Journal of the American chemical society 139 (22), 7522-7532, 2017
3002017
Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, ...
Quarterly reviews of biophysics 50, e6, 2017
2162017
A guide to structured illumination TIRF microscopy at high speed with multiple colors
LJ Young, F Ströhl, CF Kaminski
JoVE (Journal of Visualized Experiments), e53988, 2016
1152016
Single particle trajectories reveal active endoplasmic reticulum luminal flow
D Holcman, P Parutto, JE Chambers, M Fantham, LJ Young, SJ Marciniak, ...
Nature cell biology 20 (10), 1118-1125, 2018
862018
De novo design of a biologically active amyloid
R Gallardo, M Ramakers, F De Smet, F Claes, L Khodaparast, ...
Science 354 (6313), aah4949, 2016
712016
Fluorescence self-quenching from reporter dyes informs on the structural properties of amyloid clusters formed in vitro and in cells
WY Chen, LJ Young, M Lu, A Zaccone, F Strohl, N Yu, ...
Nano letters 17 (1), 143-149, 2017
662017
Imaging Aβ (1–42) fibril elongation reveals strongly polarised growth and growth incompetent states
LJ Young, GSK Schierle, CF Kaminski
Physical Chemistry Chemical Physics 19 (41), 27987-27996, 2017
602017
Three-dimensional nanoscale superconducting quantum interference device pickup loops
EJ Romans, EJ Osley, L Young, PA Warburton, W Li
Applied Physics Letters 97 (22), 2010
602010
Live-cell super-resolution microscopy reveals a primary role for diffusion in polyglutamine-driven aggresome assembly
M Lu, L Banetta, LJ Young, EJ Smith, GP Bates, A Zaccone, GSK Schierle, ...
Journal of Biological Chemistry 294 (1), 257-268, 2019
292019
Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure
RF Laine, G Goodfellow, LJ Young, J Travers, D Carroll, O Dibben, ...
Elife 7, e40183, 2018
282018
Noise performance of niobium nano-SQUIDs in applied magnetic fields
EJ Romans, S Rozhko, L Young, A Blois, L Hao, D Cox, JC Gallop
IEEE transactions on applied superconductivity 21 (3), 404-407, 2010
202010
Nanoscale click-reactive scaffolds from peptide self-assembly
APM Guttenplan, LJ Young, D Matak-Vinkovic, CF Kaminski, TPJ Knowles, ...
Journal of Nanobiotechnology 15, 1-8, 2017
122017
Acceleration of α-synuclein aggregation
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, ...
Amyloid 24 (sup1), 20-21, 2017
62017
Kinetics of amyloid fibril self-assembly by direct observation of elongation
LJ Young, CF Kaminski
Biophysical Journal 110 (3), 38a, 2016
12016
Single Particle Trajectories Reveal Active Endoplasmic Reticulum Luminal Flow
P Parutto, JE Chambers, M Fantham, L Young, S Marciniak, CF Kaminski, ...
Biophysical Journal 116 (3), 173a-174a, 2019
2019
Molecular mechanisms of neurodegeneration and therapeutic intervention
GS Schierle, N Yu, S Collins, D Pinotsi, L Young, E Nugent, C Kaminski
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 46, S67-S67, 2017
2017
Supporting Information Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides an autocatalytic amyloid amplification mechanism
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, ...
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