| Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites D Betel, A Koppal, P Agius, C Sander, C Leslie Genome biology 11 (8), 1-14, 2010 | 1417 | 2010 |
| The spectrum kernel: A string kernel for SVM protein classification C Leslie, E Eskin, WS Noble Biocomputing 2002, 564-575, 2001 | 1355 | 2001 |
| CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264, 2013 | 1265 | 2013 |
| Mismatch string kernels for discriminative protein classification CS Leslie, E Eskin, A Cohen, J Weston, WS Noble Bioinformatics 20 (4), 467-476, 2004 | 898 | 2004 |
| Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs AA Khan, D Betel, ML Miller, C Sander, CS Leslie, DS Marks Nature biotechnology 27 (6), 549-555, 2009 | 526 | 2009 |
| Foxp3 exploits a pre-existent enhancer landscape for regulatory T cell lineage specification RM Samstein, A Arvey, SZ Josefowicz, X Peng, A Reynolds, R Sandstrom, ... Cell 151 (1), 153-166, 2012 | 379 | 2012 |
| Chromatin states define tumour-specific T cell dysfunction and reprogramming M Philip, L Fairchild, L Sun, EL Horste, S Camara, M Shakiba, AC Scott, ... Nature 545 (7655), 452-456, 2017 | 362 | 2017 |
| Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia KJ Mavrakis, AL Wolfe, E Oricchio, T Palomero, K De Keersmaecker, ... Nature cell biology 12 (4), 372-379, 2010 | 358 | 2010 |
| Transcription factor Foxp3 and its protein partners form a complex regulatory network D Rudra, P Deroos, A Chaudhry, RE Niec, A Arvey, RM Samstein, ... Nature immunology 13 (10), 1010-1019, 2012 | 356 | 2012 |
| Target mRNA abundance dilutes microRNA and siRNA activity A Arvey, E Larsson, C Sander, CS Leslie, DS Marks Molecular systems biology 6 (1), 363, 2010 | 330 | 2010 |
| Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells EP Papapetrou, G Lee, N Malani, M Setty, I Riviere, LMS Tirunagari, ... Nature biotechnology 29 (1), 73-78, 2011 | 323 | 2011 |
| Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism M Peng, N Yin, S Chhangawala, K Xu, CS Leslie, MO Li Science 354 (6311), 481-484, 2016 | 320 | 2016 |
| Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting GB Loeb, AA Khan, D Canner, JB Hiatt, J Shendure, RB Darnell, ... Molecular cell 48 (5), 760-770, 2012 | 314 | 2012 |
| Evaluation of methods for modeling transcription factor sequence specificity MT Weirauch, A Cote, R Norel, M Annala, Y Zhao, TR Riley, ... Nature biotechnology 31 (2), 126-134, 2013 | 310 | 2013 |
| Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression S Lianoglou, V Garg, JL Yang, CS Leslie, C Mayr Genes & development 27 (21), 2380-2396, 2013 | 295 | 2013 |
| A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL) KJ Mavrakis, J Van Der Meulen, AL Wolfe, X Liu, E Mets, T Taghon, ... Nature genetics 43 (7), 673-678, 2011 | 281 | 2011 |
| Profile-based string kernels for remote homology detection and motif extraction R Kuang, E Ie, K Wang, K Wang, M Siddiqi, Y Freund, C Leslie Journal of bioinformatics and computational biology 3 (03), 527-550, 2005 | 269 | 2005 |
| Ibrutinib resistance in chronic lymphocytic leukemia RR Furman, S Cheng, P Lu, M Setty, AR Perez, A Guo, J Racchumi, G Xu, ... The New England journal of medicine 370 (24), 2352, 2014 | 250 | 2014 |
| Semi-supervised protein classification using cluster kernels J Weston, C Leslie, E Ie, D Zhou, A Elisseeff, WS Noble Bioinformatics 21 (15), 3241-3247, 2005 | 250 | 2005 |
| Analysis of tumour-and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S L Sevenich, RL Bowman, SD Mason, DF Quail, F Rapaport, BT Elie, ... Nature cell biology 16 (9), 876-888, 2014 | 228 | 2014 |
