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Tom Venken
Tom Venken
Laboratory of Translational Genetics, VIB
Email confirmado em kuleuven.be
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DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer
E Galle, B Thienpont, S Cappuyns, T Venken, P Busschaert, M Van Haele, ...
Clinical epigenetics 12, 1-19, 2020
662020
A novel method for hydrophobin extraction using CO 2 foam fractionation system
M Khalesi, T Venken, S Deckers, J Winterburn, Z Shokribousjein, ...
Industrial Crops and Products 43, 372-377, 2013
492013
An optimized MM/PBSA virtual screening approach applied to an HIV‐1 gp41 fusion peptide inhibitor
T Venken, D Krnavek, J Münch, F Kirchhoff, P Henklein, M De Maeyer, ...
Proteins: Structure, Function, and Bioinformatics 79 (11), 3221-3235, 2011
452011
Combined Modeling and Biophysical Characterisation of CO2 Interaction with Class II Hydrophobins: New Insight into the Mechanism Underpinning Primary Gushing
S Deckers, T Venken, M Khalesi, K Gebruers, Y Lorgouilloux, ...
Journal of the American Society of Brewing Chemists 70 (4), 249-256, 2012
292012
pKa modulation of the acid/base catalyst within GH32 and GH68: a role in substrate/inhibitor specificity?
S Yuan, K Le Roy, T Venken, W Lammens, W Van den Ende, ...
PLoS One 7 (5), e37453, 2012
252012
Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer
S Naulaerts, A Datsi, DM Borras, A Antoranz Martinez, J Messiaen, ...
Science Translational Medicine 15 (691), eadd1016, 2023
172023
Mapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein Rev
T Vercruysse, E Boons, T Venken, E Vanstreels, A Voet, J Steyaert, ...
PLoS One 8 (4), e60259, 2013
172013
Identification of a Small Molecule That Modulates Platelet Glycoprotein Ib-von Willebrand Factor Interaction
K Broos, M Trekels, RA Jose, J Demeulemeester, A Vandenbulcke, ...
Journal of Biological Chemistry 287 (12), 9461-9472, 2012
172012
Predictive value of the Leuven HRD test compared with Myriad myChoice PLUS on 468 ovarian cancer samples from the PAOLA-1/ENGOT-ov25 trial (LBA 6)
L Loverix, I Vergote, P Busschaert, A Vanderstichele, B Boeckx, T Venken, ...
Gynecologic Oncology 166, S51-S52, 2022
152022
Rapid conformational fluctuations of disordered HIV-1 fusion peptide in solution
T Venken, A Voet, M De Maeyer, G De Fabritiis, SK Sadiq
Journal of Chemical Theory and Computation 9 (7), 2870-2874, 2013
102013
Computational investigation of the HIV‐1 Rev multimerization using molecular dynamics simulations and binding free energy calculations
T Venken, D Daelemans, M De Maeyer, A Voet
Proteins: Structure, Function, and Bioinformatics 80 (6), 1633-1646, 2012
102012
Thermodynamic framework to assess low abundance DNA mutation detection by hybridization
H Willems, A Jacobs, WW Hadiwikarta, T Venken, D Valkenborg, ...
PloS one 12 (5), e0177384, 2017
92017
Immunogenomic, single-cell and spatial dissection of CD8+T cell exhaustion reveals critical determinants of cancer immunotherapy
S Naulaerts, DM Borras, AA Martinez, J Messiaen, Y Van Herck, L Gelens, ...
BioRxiv, 2021.11. 22.468617, 2021
72021
Interactions stabilizing the C-terminal helix of human phospholipid scramblase 1 in lipid bilayers: A computational study
T Venken, AS Schillinger, E Fuglebakk, N Reuter
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (7), 1200-1210, 2017
72017
PARP inhibitor predictive value of the Leuven HRD test compared with Myriad MyChoice CDx PLUS HRD on 468 ovarian cancer patients from the PAOLA-1/ENGOT-ov25 trial
L Loverix, I Vergote, P Busschaert, A Vanderstichele, T Venken, B Boeckx, ...
European Journal of Cancer 188, 131-139, 2023
62023
Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer
A Vanderstichele, P Busschaert, C Landolfo, S Olbrecht, A Coosemans, ...
NPJ Genomic Medicine 7 (1), 30, 2022
62022
d-Peptides as inhibitors of PR3-membrane interactions
K Maximova, T Venken, N Reuter, J Trylska
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (2), 458-466, 2018
62018
Computational Studies of the Active and Inactive Regulatory Domains of Response Regulator PhoP Using Molecular Dynamics Simulations
XY Qing, H Steenackers, T Venken, M De Maeyer, A Voet
Molecular informatics 36 (11), 1700031, 2017
52017
Transcription factor NKX2–1 drives serine and glycine synthesis addiction in cancer
E Heylen, P Verstraete, L Van Aerschot, SL Geeraerts, T Venken, ...
British Journal of Cancer 128 (10), 1862-1878, 2023
42023
Molecular drug susceptibility testing and strain typing of tuberculosis by DNA hybridization
HN Wood, T Venken, H Willems, A Jacobs, AJ Reis, PE Almeida da Silva, ...
Plos one 14 (2), e0212064, 2019
42019
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Artigos 1–20