Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction S Ayala-Torres, Y Chen, T Svoboda, J Rosenblatt, B Van Houten Methods 22 (2), 135-147, 2000 | 293 | 2000 |
Role of oxidative DNA damage in mitochondrial dysfunction and Huntington’s disease pathogenesis S Ayala-Peña Free Radical Biology and Medicine 62, 102-110, 2013 | 147 | 2013 |
Mitochondrial DNA damage is a hallmark of chemically induced and the R6/2 transgenic model of Huntington's disease K Acevedo-Torres, L Berríos, N Rosario, V Dufault, S Skatchkov, MJ Eaton, ... DNA repair 8 (1), 126-136, 2009 | 141 | 2009 |
Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington’s disease Z Xun, S Rivera-Sanchez, S Ayala-Peña, J Lim, H Budworth, EM Skoda, ... Cell reports 2 (5), 1137-1142, 2012 | 138 | 2012 |
Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease A Siddiqui, S Rivera-Sánchez, MR Castro, K Acevedo-Torres, A Rane, ... Free Radical Biology and Medicine 53 (7), 1478-1488, 2012 | 134 | 2012 |
Aging increases mitochondrial DNA damage and oxidative stress in liver of rhesus monkeys MR Castro, E Suarez, E Kraiselburd, A Isidro, J Paz, L Ferder, ... Experimental gerontology 47 (1), 29-37, 2012 | 120 | 2012 |
Suppression of somatic expansion delays the onset of pathophysiology in a mouse model of Huntington’s disease H Budworth, FR Harris, P Williams, DY Lee, A Holt, J Pahnke, B Szczesny, ... PLoS genetics 11 (8), e1005267, 2015 | 90 | 2015 |
Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats N Escobales, RE Nuñez, S Jang, R Parodi-Rullan, S Ayala-Peña, ... Journal of molecular and cellular cardiology 77, 136-146, 2014 | 83 | 2014 |
Mitochondrial targeting of XJB-5-131 attenuates or improves pathophysiology in HdhQ150 animals with well-developed disease phenotypes A Polyzos, A Holt, C Brown, C Cosme, P Wipf, A Gomez-Marin, MR Castro, ... Human molecular genetics 25 (9), 1792-1802, 2016 | 55 | 2016 |
Estrogen-induced microsatellite DNA alterations are associated with Syrian hamster kidney tumorigenesis. AV Hodgson, S Ayala-Torres, EB Thompson, JG Liehr Carcinogenesis 19 (12), 2169-2172, 1998 | 52 | 1998 |
Characteristics of 25-hydroxycholesterol-induced apoptosis in the human leukemic cell line CEM S Ayala-Torres, PC Moller, BH Johnson, EB Thompson Experimental cell research 235 (1), 35-47, 1997 | 46 | 1997 |
Apoptosis induced by oxysterol in CEM cells is associated with negative regulation of c-myc S Ayala-Torres, F Zhou, EB Thompson Experimental cell research 246 (1), 193-202, 1999 | 42 | 1999 |
Oxysterols and apoptosis: evidence for gene regulation outside the cholesterol pathway EB Thompson, S Ayala-Torres Biochemistry and Function of Sterols, 65-72, 2020 | 37 | 2020 |
Mitochondrial DNA damage as driver of cellular outcomes CA Nadalutti, S Ayala-Peña, JH Santos American Journal of Physiology-Cell Physiology 322 (2), C136-C150, 2022 | 32 | 2022 |
Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with systemic lupus erythematosus L López-López, M Nieves-Plaza, M del R Castro, YM Font, ... Lupus 23 (11), 1133-1141, 2014 | 32 | 2014 |
Glucocorticoids, oxysterols, and cAMP with glucocorticoids each cause apoptosis of CEM cells and suppress c-myc EB Thompson, RD Medh, F Zhou, S Ayala-Torres, N Ansari, W Zhang, ... The Journal of steroid biochemistry and molecular biology 69 (1-6), 453-461, 1999 | 32 | 1999 |
Requirement of the Saccharomyces cerevisiae APN1 gene for the repair of mitochondrial DNA alkylation damage K Acevedo‐Torres, S Fonseca‐Williams, S Ayala‐Torres, ... Environmental and molecular mutagenesis 50 (4), 317-327, 2009 | 31 | 2009 |
Oxysterol sensitive and resistant lymphoid cells: correlation with regulation of cellular nucleic acid binding protein mRNA S Ayala-Torres, BH Johnson, EB Thompson The Journal of Steroid Biochemistry and Molecular Biology 48 (4), 307-315, 1994 | 30 | 1994 |
Glucocorticoid/oxysterol-induced DNA lysis in human leukemic cells BH Johnson, S Ayala-Torres, LNL Chan, M El-Naghy, EB Thompson The Journal of Steroid Biochemistry and Molecular Biology 61 (1-2), 35-45, 1997 | 24 | 1997 |
Mitochondrial DNA integrity is maintained by APE1 in carcinogen-induced colorectal cancer J Ballista-Hernández, M Martínez-Ferrer, R Vélez, C Climent, ... Molecular Cancer Research 15 (7), 831-841, 2017 | 22 | 2017 |