| TNF-α signals through PKCζ/NF-κB to alter the tight junction complex and increase retinal endothelial cell permeability CA Aveleira, CM Lin, SF Abcouwer, AF Ambrosio, DA Antonetti Diabetes 59 (11), 2872-2882, 2010 | 448 | 2010 |
| Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024 AF Ambrósio, P Soares-da-Silva, CM Carvalho, AP Carvalho Neurochemical research 27, 121-130, 2002 | 391 | 2002 |
| Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy EC Leal, A Manivannan, KI Hosoya, T Terasaki, J Cunha-Vaz, ... Investigative ophthalmology & visual science 48 (11), 5257-5265, 2007 | 302 | 2007 |
| PINK1/PARKIN signalling in neurodegeneration and neuroinflammation PMJ Quinn, PI Moreira, AF Ambrósio, CH Alves Acta neuropathologica communications 8 (1), 189, 2020 | 257 | 2020 |
| Contribution of microglia-mediated neuroinflammation to retinal degenerative diseases MH Madeira, R Boia, PF Santos, AF Ambrósio, AR Santiago Mediators of inflammation 2015, 2015 | 243 | 2015 |
| Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes EC Leal, J Martins, P Voabil, J Liberal, C Chiavaroli, J Bauer, ... Diabetes 59 (10), 2637-2645, 2010 | 177 | 2010 |
| Inside the diabetic brain: role of different players involved in cognitive decline JM Gaspar, FI Baptista, MP Macedo, AF Ambrosio ACS chemical neuroscience 7 (2), 131-142, 2016 | 160 | 2016 |
| Diabetic cardiomyopathy: definition, diagnosis, and therapeutic implications S Paolillo, F Marsico, M Prastaro, F Renga, L Esposito, F De Martino, ... Heart failure clinics 15 (3), 341-347, 2019 | 155 | 2019 |
| Methamphetamine transiently increases the blood–brain barrier permeability in the hippocampus: role of tight junction proteins and matrix metalloproteinase-9 T Martins, S Baptista, J Gonçalves, E Leal, N Milhazes, F Borges, ... Brain research 1411, 28-40, 2011 | 142 | 2011 |
| Heme oxygenase-1 protects retinal endothelial cells against high glucose-and oxidative/nitrosative stress-induced toxicity ÁF Castilho, CA Aveleira, EC Leal, NF Simões, CR Fernandes, ... Public Library of Science 7 (8), e42428, 2012 | 111 | 2012 |
| Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood–retinal barrier in a type 2 diabetes animal model A Gonçalves, E Leal, A Paiva, E Teixeira Lemos, F Teixeira, CF Ribeiro, ... Diabetes, Obesity and Metabolism 14 (5), 454-463, 2012 | 103 | 2012 |
| High glucose induces caspase-independent cell death in retinal neural cells AR Santiago, AJ Cristovao, PF Santos, CM Carvalho, AF Ambrosio Neurobiology of disease 25 (3), 464-472, 2007 | 101 | 2007 |
| Inhibition of N-, P/Q-and other types of Ca2+ channels in rat hippocampal nerve terminals by the adenosine A1 receptor AF Ambrósio, JO Malva, AP Carvalho, CM Carvalho European journal of pharmacology 340 (2-3), 301-310, 1997 | 96 | 1997 |
| Nitric oxide stimulates the proliferation of neural stem cells bypassing the epidermal growth factor receptor BP Carreira, MI Morte, Â Inácio, G Costa, J Rosmaninho-Salgado, ... Stem cells 28 (7), 1219-1230, 2010 | 93 | 2010 |
| Regulation of claudins in blood-tissue barriers under physiological and pathological states A Gonçalves, AF Ambrósio, R Fernandes Tissue barriers 1 (3), e24782, 2013 | 91 | 2013 |
| Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists AF Ambrósio, AP Silva, JO Malva, P Soares-da-Silva, AP Carvalho, ... Neuropharmacology 38 (9), 1349-1359, 1999 | 91 | 1999 |
| Role of Microglia Adenosine A2A Receptors in Retinal and Brain Neurodegenerative Diseases AR Santiago, FI Baptista, PF Santos, G Cristóvão, AF Ambrósio, ... Mediators of inflammation 2014, 2014 | 90 | 2014 |
| Diabetes changes the levels of ionotropic glutamate receptors in the rat retina AR Santiago, JM Gaspar, FI Baptista, AJ Cristóvão, PF Santos, ... Molecular vision 15, 1620, 2009 | 90 | 2009 |
| Neuroprotective strategies for retinal ganglion cell degeneration: current status and challenges ahead R Boia, N Ruzafa, ID Aires, X Pereiro, AF Ambrósio, E Vecino, ... International journal of molecular sciences 21 (7), 2262, 2020 | 89 | 2020 |
| Neurotoxic/neuroprotective profile of carbamazepine, oxcarbazepine and two new putative antiepileptic drugs, BIA 2-093 and BIA 2-024 AF Ambrósio, AP Silva, I Araújo, JO Malva, P Soares-da-Silva, ... European journal of pharmacology 406 (2), 191-201, 2000 | 89 | 2000 |
