The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation A Langdon, N Crook, G Dantas Genome medicine 8, 1-16, 2016 | 1117 | 2016 |
Engineered Alkane‐Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties R Fasan, MM Chen, NC Crook, FH Arnold Angewandte Chemie International Edition 46 (44), 8414-8418, 2007 | 325 | 2007 |
Design of synthetic yeast promoters via tuning of nucleosome architecture KA Curran, NC Crook, AS Karim, A Gupta, AM Wagman, HS Alper Nature communications 5 (1), 4002, 2014 | 166 | 2014 |
A liquid metal mediated metallic coating for antimicrobial and antiviral fabrics KY Kwon, S Cheeseman, A Frias‐De‐Diego, H Hong, J Yang, W Jung, ... Advanced Materials 33 (45), 2104298, 2021 | 146 | 2021 |
In vivo continuous evolution of genes and pathways in yeast N Crook, J Abatemarco, J Sun, JM Wagner, A Schmitz, HS Alper Nature communications 7 (1), 13051, 2016 | 146 | 2016 |
Adaptive strategies of the candidate probiotic E. coli Nissle in the mammalian gut N Crook, A Ferreiro, AJ Gasparrini, MW Pesesky, MK Gibson, B Wang, ... Cell host & microbe 25 (4), 499-512. e8, 2019 | 132 | 2019 |
Multiscale evolutionary dynamics of host-associated microbiomes A Ferreiro, N Crook, AJ Gasparrini, G Dantas Cell 172 (6), 1216-1227, 2018 | 120 | 2018 |
Barriers to genome editing with CRISPR in bacteria JM Vento, N Crook, CL Beisel Journal of Industrial Microbiology and Biotechnology 46 (9-10), 1327-1341, 2019 | 116 | 2019 |
Optimization of a yeast RNA interference system for controlling gene expression and enabling rapid metabolic engineering NC Crook, AC Schmitz, HS Alper ACS synthetic biology 3 (5), 307-313, 2014 | 81 | 2014 |
Improved product‐per‐glucose yields in P450‐dependent propane biotransformations using engineered Escherichia coli R Fasan, NC Crook, MW Peters, P Meinhold, T Buelter, M Landwehr, ... Biotechnology and bioengineering 108 (3), 500-510, 2011 | 70 | 2011 |
Re-engineering multicloning sites for function and convenience NC Crook, ES Freeman, HS Alper Nucleic acids research 39 (14), e92-e92, 2011 | 62 | 2011 |
Carotenoids and their health benefits as derived via their interactions with gut microbiota A Eroglu, IS Al’Abri, RE Kopec, N Crook, T Bohn Advances in Nutrition 14 (2), 238-255, 2023 | 58 | 2023 |
Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin EM Brustad, VS Lelyveld, CD Snow, N Crook, ST Jung, FM Martinez, ... Journal of molecular biology 422 (2), 245-262, 2012 | 50 | 2012 |
In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii D Durmusoglu, IS Al’Abri, SP Collins, J Cheng, A Eroglu, CL Beisel, ... ACS synthetic biology 10 (5), 1039-1052, 2021 | 48 | 2021 |
Discovery and delivery strategies for engineered live biotherapeutic products MK Heavey, D Durmusoglu, N Crook, AC Anselmo Trends in biotechnology 40 (3), 354-369, 2022 | 45 | 2022 |
Innovation at the intersection of synthetic and systems biology AM Lanza, NC Crook, HS Alper Current Opinion in Biotechnology 23 (5), 712-717, 2012 | 39 | 2012 |
Using flux balance analysis to guide microbial metabolic engineering KA Curran, NC Crook, HS Alper Microbial Metabolic Engineering: Methods and Protocols, 197-216, 2012 | 39 | 2012 |
Classical strain improvement N Crook, HS Alper Engineering complex phenotypes in industrial strains, 1-33, 2012 | 37* | 2012 |
Identification of gene knockdown targets conferring enhanced isobutanol and 1-butanol tolerance to Saccharomyces cerevisiae using a tunable RNAi screening … N Crook, J Sun, N Morse, A Schmitz, HS Alper Applied microbiology and biotechnology 100, 10005-10018, 2016 | 28 | 2016 |
Improvement of lactic acid production in Saccharomyces cerevisiae by a deletion of ssb1 JJ Lee, N Crook, J Sun, HS Alper Journal of Industrial Microbiology and Biotechnology 43 (1), 87-96, 2016 | 28 | 2016 |